ARDELYX INC ARDX
COM · Common Stock · CUSIP 039697107 · ISIN US0396971071
Company in Fremont, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersFremont, CA
- Founded2007
- Websiteardelyx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($456.5k this quarter). Holder counts are more reliable. Shares outstanding: 249.2m as of 2026-07-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $5.11. Options: 9 managers hold calls ($8.6m notional), 8 hold puts ($6.8m).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 84 |
| Q4 2022 | 106 |
| Q1 2023 | 131 |
| Q2 2023 | 147 |
| Q3 2023 | 151 |
| Q4 2023 | 163 |
| Q1 2024 | 190 |
| Q2 2024 | 198 |
| Q3 2024 | 204 |
| Q4 2024 | 214 |
| Q1 2025 | 222 |
| Q2 2025 | 207 |
| Q3 2025 | 223 |
| Q4 2025 | 229 |
| Q1 2026 | 242 |
| Q2 2026 | 249 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 103 | 87 |
| Q4 2024 | 111 | 95 |
| Q1 2025 | 128 | 86 |
| Q2 2025 | 104 | 107 |
| Q3 2025 | 116 | 93 |
| Q4 2025 | 111 | 110 |
| Q1 2026 | 147 | 91 |
| Q2 2026 | 128 | 121 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $10.8m | $9.7m | 0.90 |
| Q4 2025 | $9.9m | $7.8m | 0.79 |
| Q1 2026 | $9.8m | $6.0m | 0.61 |
| Q2 2026 | $8.6m | $6.8m | 0.79 |
Biggest buyers
| Rubric Capital Management LP | Added | +14.3m |
| AIGH Capital Management LLC | New | +3.2m |
| BlackRock, Inc. | Added | +2.3m |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. | Added | +1.4m |
| VANGUARD PORTFOLIO MANAGEMENT LLC | Added | +1.4m |
| Invesco Ltd. | Added | +1.1m |
| TWO SIGMA INVESTMENTS, LP | Added | +935.8k |
| PANAGORA ASSET MANAGEMENT INC | New | +890.9k |
| ExodusPoint Capital Management, LP | New | +752.9k |
| SCHRODER INVESTMENT MANAGEMENT GROUP | Added | +741.5k |
Biggest sellers
| MILLENNIUM MANAGEMENT LLC | Reduced | -3.9m |
| Point72 Asset Management, L.P. | Sold out | -3.0m |
| CITADEL ADVISORS LLC | Reduced | -2.4m |
| Freestone Grove Partners LP | Reduced | -1.6m |
| MARSHALL WACE, LLP | Reduced | -1.5m |
| J. Goldman & Co LP | Reduced | -1.4m |
| Nuveen, LLC | Reduced | -1.2m |
| JANE STREET GROUP, LLC | Sold out | -1.2m |
| Eversept Partners, LP | Reduced | -551.1k |
| Ishara Investments LP | Sold out | -451.0k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $1.6m305.6k shares |
| MILLENNIUM MANAGEMENT LLC | Added | $1.5m300.0k shares |
| GROUP ONE TRADING LLC | Added | $1.4m267.7k shares |
| Stonepine Capital Management, LLC | Unchanged | $1.1m150.0k shares |
| JANE STREET GROUP, LLC | Reduced | $875.2k171.6k shares |
| SIMPLEX TRADING, LLC | Added | $773.7k151.7k shares |
| Caption Management, LLC | Unchanged | $765.0k150.0k shares |
| CITADEL ADVISORS LLC | Reduced | $442.7k86.8k shares |
| RAYMOND JAMES FINANCIAL INC | Unchanged | $250.0k50.0k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $2.0m398.8k shares |
| CITADEL ADVISORS LLC | Added | $1.5m303.0k shares |
| JANE STREET GROUP, LLC | Reduced | $1.0m205.7k shares |
| Caption Management, LLC | Unchanged | $1.0m200.0k shares |
| SIMPLEX TRADING, LLC | Added | $388.6k76.2k shares |
| MILLENNIUM MANAGEMENT LLC | New | $365.7k71.7k shares |
| IMC-Chicago, LLC | Added | $204.5k40.1k shares |
| GROUP ONE TRADING LLC | Reduced | $203.0k39.8k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Rubric Capital Management LP 13G · institution new · filed 2026-08-14 | 6.6% |
| INTEGRATED CORE STRATEGIES (US) LLC 13G · passive investor -1.7 pts · filed 2026-08-11 | 5.7% |
| STATE STREET CORP 13G · institution +0.6 pts · filed 2026-05-12 | 5.5% |
Fell to 5% or below in the last year: JANUS HENDERSON GROUP PLC (3.4%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 1 | $2.0m | 6 | $1.1m | $472.3k |
| Q1 2025 | 1 | $1.4m | 4 | $877.9k | $667.9k |
| Q2 2025 | 1 | $3.4m | 6 | $708.9k | $368.3k |
| Q3 2025 | 0 | — | 6 | $996.9k | $489.6k |
| Q4 2025 | 0 | — | 6 | $453.0k | — |
| Q1 2026 | 1 | $1.9m | 8 | $1.4m | $853.2k |
| Q2 2026 | 0 | — | 8 | $1.8m | $1.3m |
| Q3 2026 | 0 | — | 8 | $697.4k | $210.8k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-08-21 | RAAB MICHAEL President & CEO, director | Sold | $226.1k58.6k shares |
| 2026-08-21 | Bishop John E Officer | Sold | $76.2k19.8k shares |
| 2026-08-21 | Brady James Parker Chief Human Resources Officer | Sold | $58.4k15.1k shares |
| 2026-08-21 | Williams Laura A Chief Patient Officer | Sold | $41.5k10.7k shares |
| 2026-08-21 | Foster Eric Duane Chief Commercial Officer | Sold | $33.0k8.6k shares |
| 2026-08-21 | Kelliher Mike Chief Business Officer | Sold | $29.9k7.8k shares |
| 2026-08-21 | Reilly Joseph James Officer | Sold | $15.4k4.0k shares |
| 2026-08-21 | Hohenleitner Susan Chief Financial Officer | Sold | $6.0k1.6k shares |
| 2026-07-15 | RAAB MICHAEL President & CEO, director | Sold plan | $210.8k41.7k shares |
| 2026-06-18 | Williams Laura A Chief Patient Officer | Sold plan | $490.6k81.9k shares |
| 2026-06-15 | RAAB MICHAEL President & CEO, director | Sold plan | $236.2k41.7k shares |
| 2026-05-21 | RAAB MICHAEL President & CEO, director | Sold | $343.3k54.7k shares |
| 2026-05-21 | Foster Eric Duane Chief Commercial Officer | Sold | $50.1k8.0k shares |
| 2026-05-21 | Kelliher Mike Chief Business Officer | Sold | $45.4k7.2k shares |
| 2026-05-21 | Williams Laura A Chief Patient Officer | Sold | $43.8k7.0k shares |
| 2026-05-21 | Reilly Joseph James Officer | Sold | $23.3k3.7k shares |
| 2026-05-21 | Bishop John E Officer | Sold | $14.5k2.3k shares |
| 2026-05-21 | Brady James Parker Chief Human Resources Officer | Sold | $11.6k1.8k shares |
| 2026-05-21 | Hohenleitner Susan Chief Financial Officer | Sold | $9.1k1.5k shares |
| 2026-05-15 | RAAB MICHAEL President & CEO, director | Sold plan | $261.7k41.7k shares |
| 2026-04-15 | RAAB MICHAEL President & CEO, director | Sold plan | $262.1k41.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 23.5m $119.9m | Added +2.3m |
| Rubric Capital Management LP 0.76% of their portfolio | 16.2m $82.6m | Added +14.3m |
| MILLENNIUM MANAGEMENT LLC 0.05% of their portfolio | 13.9m $70.9m | Reduced -3.9m |
| STATE STREET CORP 0.00% of their portfolio | 13.4m $68.1m | Reduced -248.2k |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 10.5m $53.4m | Added +106.0k |
| NOMURA ASSET MANAGEMENT INTERNATIONAL INC. 0.07% of their portfolio | 9.5m $48.7m | Added +1.4m |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 8.0m $40.9m | Added +1.4m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 6.4m $32.7m | Added +394.3k |
| Jupiter Topco LLC 0.01% of their portfolio | 5.3m $27.0m | First filing |
| TWO SIGMA INVESTMENTS, LP 0.02% of their portfolio | 5.2m $26.6m | Added +935.8k |
| Nuveen, LLC 0.00% of their portfolio | 4.0m $20.4m | Reduced -1.2m |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 3.7m $18.8m | Added +468.8k |
| AIGH Capital Management LLC 1.48% of their portfolio | 3.2m $16.3m | New |
| MORGAN STANLEY 0.00% of their portfolio | 2.4m $12.2m | Added +680.6k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 2.3m $11.8m | Reduced -123.2k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 2.3m $11.6m | Added +209.1k |
| Rock Springs Capital Management LP 0.56% of their portfolio | 2.2m $11.4m | Reduced -57.7k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 2.2m $11.3m | Added +97.7k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 2.2m $11.0m | Reduced -173.5k |
| Qube Research & Technologies Ltd 0.01% of their portfolio | 2.1m $10.7m | Reduced -344.9k |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 1.8m $9.8m | Reduced -93.0k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 1.8m $8.9m | Added +76.7k |
| Eversept Partners, LP 0.47% of their portfolio | 1.7m $8.6m | Reduced -551.1k |
| J. Goldman & Co LP 0.28% of their portfolio | 1.6m $8.1m | Reduced -1.4m |
| Invesco Ltd. 0.00% of their portfolio | 1.4m $7.0m | Added +1.1m |
| FIRST TRUST ADVISORS LP 0.00% of their portfolio | 1.3m $6.6m | Reduced -197.2k |
| Hennion & Walsh Asset Management, Inc. 0.18% of their portfolio | 1.2m $6.2m | Added +210.2k |
| SCHRODER INVESTMENT MANAGEMENT GROUP 0.00% of their portfolio | 1.2m $6.1m | Added +741.5k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 1.0m $5.3m | Reduced -2.4m |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 916.0k $4.7m | Added +214.1k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 892.6k $4.6m | Reduced -379.8k |
| PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio | 890.9k $4.5m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 810.3k $4.1m | Added +111.6k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 770.9k $3.9m | Added +62.3k |
| ExodusPoint Capital Management, LP 0.04% of their portfolio | 752.9k $3.8m | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 749.7k $3.8m | Added +48.9k |
| Squarepoint Ops LLC 0.01% of their portfolio | 715.3k $3.6m | Added +18.0k |
| SECTOR GAMMA AS 0.76% of their portfolio | 686.8k $3.5m | Added +170.7k |
| Trexquant Investment LP 0.02% of their portfolio | 660.6k $3.4m | Reduced -144.1k |
| Redmile Group, LLC 0.22% of their portfolio | 641.8k $3.3m | Reduced -91.6k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 562.7k $2.9m | Added +76.0k |
| UBS Group AG 0.00% of their portfolio | 551.7k $2.8m | Reduced -136.9k |
| Jump Financial, LLC 0.02% of their portfolio | 537.0k $2.7m | New |
| Krensavage Asset Management, LLC 1.04% of their portfolio | 534.5k $2.7m | Added +34.5k |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 486.4k $2.5m | Added +45.7k |
| MACKENZIE FINANCIAL CORP 0.00% of their portfolio | 474.1k $2.4m | New |
| Swiss National Bank 0.00% of their portfolio | 467.6k $2.4m | Reduced -13.2k |
| HUSSMAN STRATEGIC ADVISORS, INC. 0.49% of their portfolio | 420.0k $2.1m | New |
| Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% of their portfolio | 411.4k $2.1m | Added +54.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 359.6k $1.8m | Added +65.9k |
| Clay Northam Wealth Management, LLC 0.84% of their portfolio | 334.1k $1.7m | Added +2.1k |
| CITIGROUP INC 0.00% of their portfolio | 311.0k $1.6m | Added +244.9k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 305.8k $1.6m | Added +14.0k |
| DIADEMA PARTNERS LP 0.55% of their portfolio | 303.0k $1.5m | New |
| Raiffeisen Bank International AG 0.02% of their portfolio | 300.0k $1.6m | Unchanged |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 295.6k $1.5m | Reduced -7.5k |
| Y-Intercept (Hong Kong) Ltd 0.03% of their portfolio | 290.3k $1.5m | Reduced -160.5k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 280.5k $1.4m | Added +137.4k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 264.8k $1.6m | Unchanged |
| Knott David M Jr 0.71% of their portfolio | 263.2k $1.3m | Added +56.2k |
| Freestone Grove Partners LP 0.01% of their portfolio | 253.7k $1.3m | Reduced -1.6m |
| IEQ CAPITAL, LLC 0.01% of their portfolio | 240.8k $1.2m | Reduced -54.7k |
| Headlands Technologies LLC 0.13% of their portfolio | 240.8k $1.2m | Added +18.3k |
| Pekin Hardy Strauss, Inc. 0.10% of their portfolio | 226.4k $1.2m | Reduced -29.4k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 225.8k $1.2m | Reduced -204.3k |
| LPL Financial LLC 0.00% of their portfolio | 210.6k $1.1m | Reduced -708 |
| Thrivent Financial for Lutherans 0.00% of their portfolio | 210.6k $1.1m | Added +14.2k |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 206.2k $1.1m | Reduced -201.7k |
| Virtus Investment Advisers, LLC 0.24% of their portfolio | 204.4k $1.0m | Added +68.4k |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 201.4k $1.0m | Added +16.2k |
| MONIMUS CAPITAL MANAGEMENT, LP 0.25% of their portfolio | 195.6k $997.6k | Reduced -248.2k |
| Legal & General Group Plc 0.00% of their portfolio | 195.5k $996.9k | Reduced -11.2k |
| Carrera Capital Advisors 0.15% of their portfolio | 195.2k $995.3k | Added +4.0k |
| Walleye Capital LLC 0.00% of their portfolio | 171.0k $872.2k | New |
| VANGUARD ASSET MANAGEMENT, Ltd 0.00% of their portfolio | 166.5k $849.3k | Unchanged |
| SEI INVESTMENTS CO 0.00% of their portfolio | 152.1k $775.5k | Added +17.6k |
| SIMPLEX TRADING, LLC 0.02% of their portfolio | 151.4k $772.3k | Reduced -23.4k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 143.4k $731.5k | Reduced -16.3k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 142.7k $727.5k | Added +9.6k |
| PFG Investments, LLC 0.03% of their portfolio | 137.7k $702.1k | Reduced -200 |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 136.5k $699.3k | Reduced -4.8k |
| Inspire Investing, LLC 0.03% of their portfolio | 134.3k $684.7k | Added +47.4k |
| Caption Management, LLC 0.02% of their portfolio | 130.0k $663.0k | Added +25.8k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 129.4k $659.8k | Added +128.4k |
| Lion Point Capital, LP 3.14% of their portfolio | 128.7k $656.1k | Unchanged |
| SECTORAL ASSET MANAGEMENT INC 0.44% of their portfolio | 122.4k $624.2k | Unchanged |
| Trust Co 0.05% of their portfolio | 116.4k $593.5k | New |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 115.8k $590.5k | Added +3.4k |
| Pavaki Capital Management LLC 0.33% of their portfolio | 115.0k $586.5k | Unchanged |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 112.9k $575.8k | Unchanged |
| GROUP ONE TRADING LLC 0.02% of their portfolio | 105.9k $540.1k | Reduced -14.4k |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 105.3k $537.2k | Reduced -76.7k |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 104.9k $535.1k | Reduced -2.2k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 103.5k $527.8k | Unchanged |
| SG Americas Securities, LLC 0.00% of their portfolio | 103.2k $526.0k | Reduced -3.6k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 102.6k $523.3k | Added +46.3k |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 100.5k $509.3k | Added +6.6k |
| DekaBank Deutsche Girozentrale 0.00% of their portfolio | 100.0k $591.0k | Unchanged |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 97.9k $497.0k | Reduced -17.4k |
| DIVERSIFIED TRUST CO 0.01% of their portfolio | 97.2k $496.0k | New |