ALTIMMUNE INC ALT
COM NEW · Common Stock · CUSIP 02155H200 · ISIN US02155H2004
American biopharmaceutical company
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersGaithersburg, MD
- Founded1997
- Websitealtimmune.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.8m this quarter). Holder counts are more reliable. Shares outstanding: 49.2m as of 2022-11-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $16.45. Options: 23 managers hold calls ($60.0m notional), 11 hold puts ($7.3m).
Trends to Q4 2022
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 122 |
| Q4 2022 | 129 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2022 | $50.0m | $19.7m | 0.39 |
| Q4 2022 | $60.0m | $7.3m | 0.12 |
Biggest buyers
| STATE STREET CORP | Added | +2.5m |
| Avidity Partners Management LP | Added | +1.3m |
| PICTET ASSET MANAGEMENT SA | New | +1.1m |
| CITADEL ADVISORS LLC | Added | +1.0m |
| JENNISON ASSOCIATES LLC | Added | +747.3k |
| VANGUARD GROUP INC | Added | +505.4k |
| Invesco Ltd. | New | +425.8k |
| UBS Group AG | Added | +326.8k |
| Rafferty Asset Management, LLC | Added | +298.6k |
| Woodline Partners LP | Added | +285.9k |
Biggest sellers
| JANUS HENDERSON GROUP PLC | Reduced | -4.4m |
| Driehaus Capital Management LLC | Sold out | -1.2m |
| BAKER BROS. ADVISORS LP | Reduced | -1.1m |
| Balyasny Asset Management L.P. | Reduced | -857.9k |
| Cormorant Asset Management, LP | Reduced | -842.9k |
| Logos Global Management LP | Sold out | -750.0k |
| Boxer Capital, LLC | Sold out | -500.0k |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -490.2k |
| JPMORGAN CHASE & CO | Reduced | -471.9k |
| Ghost Tree Capital, LLC | Sold out | -435.0k |
Biggest calls
| Ikarian Capital, LLC | Reduced | $9.5m577.4k shares |
| Caption Management, LLC | Reduced | $9.0m547.3k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $7.0m428.5k shares |
| Cormorant Asset Management, LP | New | $6.6m400.0k shares |
| GROUP ONE TRADING LLC | Reduced | $5.4m327.0k shares |
| SIMPLEX TRADING, LLC | Added | $4.4m269.7k shares |
| CITADEL ADVISORS LLC | Reduced | $3.0m180.4k shares |
| SILVERARC CAPITAL MANAGEMENT, LLC | New | $2.6m160.0k shares |
| DCF Advisers, LLC | Added | $2.5m149.0k shares |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | $1.9m113.4k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $2.7m161.3k shares |
| CITADEL ADVISORS LLC | Reduced | $1.6m94.4k shares |
| SIMPLEX TRADING, LLC | Reduced | $1.1m68.0k shares |
| IMC-Chicago, LLC | Reduced | $789.6k48.0k shares |
| GROUP ONE TRADING LLC | Reduced | $633.3k38.5k shares |
| WOLVERINE TRADING, LLC | Reduced | $209.0k12.7k shares |
| Belvedere Trading LLC | New | $187.5k11.4k shares |
| Parallax Volatility Advisers, L.P. | Unchanged | $161.2k9.8k shares |
| Walleye Trading LLC | New | $23.0k1.4k shares |
| Cutler Group LLC / CA | Added | $1.0k5.6k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Deep Track Capital, LP 13G · passive investor new · filed 2026-04-30 | 10.0% |
| TCG Crossover GP II, LLC 13G · passive investor new · filed 2026-05-01 | 9.8% |
| BlackRock, Inc. 13G · institution -1.1 pts · filed 2025-07-16 | 7.6% |
| VIKING GLOBAL INVESTORS LP 13G · passive investor new · filed 2026-05-01 | 6.7% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor new · filed 2026-05-01 | 6.5% |
| STATE STREET CORP 13G · institution new · filed 2026-05-12 | 5.5% |
Fell to 5% or below in the last year: TANG CAPITAL MANAGEMENT LLC (0.3%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales in Q4 2022
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q1 2021 | 0 | — | 0 | — | — |
| Q2 2021 | 0 | — | 0 | — | — |
| Q3 2021 | 0 | — | 0 | — | — |
| Q4 2021 | 0 | — | 0 | — | — |
| Q1 2022 | 0 | — | 1 | $225.6k | — |
| Q2 2022 | 1 | $13.4k | 2 | $720.7k | — |
| Q3 2022 | 0 | — | 3 | $1.1m | — |
| Q4 2022 | 0 | — | 1 | $300.2k | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2022-12-22 | Pisano Wayne Director | Sold | $300.2k20.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q4 2022
| Manager | Shares | Change |
|---|---|---|
| STATE STREET CORP 0.01% of their portfolio | 5.9m $97.3m | Added +2.5m |
| Avidity Partners Management LP 1.53% of their portfolio | 4.0m $65.6m | Added +1.3m |
| JANUS HENDERSON GROUP PLC 0.05% of their portfolio | 3.8m $63.1m | Reduced -4.4m |
| Nuveen Asset Management, LLC 0.02% of their portfolio | 3.3m $53.7m | Added +52.1k |
| TANG CAPITAL MANAGEMENT LLC 6.45% of their portfolio | 2.7m $44.4m | Added +100.0k |
| Cormorant Asset Management, LP 2.87% of their portfolio | 2.6m $42.8m | Reduced -842.9k |
| VANGUARD GROUP INC 0.00% of their portfolio | 2.5m $41.7m | Added +505.4k |
| BlackRock Inc. 0.00% of their portfolio | 1.4m $22.3m | Added +134.7k |
| Woodline Partners LP 0.30% of their portfolio | 1.3m $21.5m | Added +285.9k |
| MARSHALL WACE, LLP 0.05% of their portfolio | 1.2m $20.4m | Added +140.9k |
| CITADEL ADVISORS LLC 0.02% of their portfolio | 1.2m $19.1m | Added +1.0m |
| PICTET ASSET MANAGEMENT SA 0.03% of their portfolio | 1.1m $17.7m | New |
| JENNISON ASSOCIATES LLC 0.02% of their portfolio | 928.8k $15.3m | Added +747.3k |
| TWO SIGMA ADVISERS, LP 0.04% of their portfolio | 925.3k $15.2m | Added +56.5k |
| TWO SIGMA INVESTMENTS, LP 0.04% of their portfolio | 776.3k $12.8m | Reduced -201.3k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 767.8k $12.6m | Added +32.1k |
| Laurion Capital Management LP 0.35% of their portfolio | 751.3k $12.4m | Added +1.2k |
| ARDSLEY ADVISORY PARTNERS LP 2.94% of their portfolio | 704.8k $11.6m | Reduced -223.2k |
| BAKER BROS. ADVISORS LP 0.06% of their portfolio | 653.6k $10.8m | Reduced -1.1m |
| Rafferty Asset Management, LLC 0.08% of their portfolio | 598.9k $9.9m | Added +298.6k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 529.6k $8.7m | Added +267.4k |
| RENAISSANCE TECHNOLOGIES LLC 0.01% of their portfolio | 508.0k $8.4m | Reduced -490.2k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 438.9k $7.2m | Reduced -37.2k |
| MORGAN STANLEY 0.00% of their portfolio | 434.6k $7.1m | Reduced -157.3k |
| Invesco Ltd. 0.00% of their portfolio | 425.8k $7.0m | New |
| UBS Group AG 0.00% of their portfolio | 383.1k $6.3m | Added +326.8k |
| SPHERA FUNDS MANAGEMENT LTD. 1.97% of their portfolio | 380.3k $6.3m | Reduced -220.0k |
| BARCLAYS PLC 0.01% of their portfolio | 361.2k $5.9m | First filing |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.01% of their portfolio | 352.1k $5.8m | Added +176.8k |
| SECTORAL ASSET MANAGEMENT INC 1.09% of their portfolio | 342.5k $5.6m | Added +73.4k |
| Tri Locum Partners LP 2.37% of their portfolio | 325.7k $5.4m | Added +168.4k |
| CITIGROUP INC 0.01% of their portfolio | 291.8k $4.8m | Added +19.7k |
| Ikarian Capital, LLC 1.87% of their portfolio | 273.4k $4.5m | Reduced -198.6k |
| JANE STREET GROUP, LLC 0.01% of their portfolio | 245.1k $4.0m | Added +14.6k |
| Beirne Wealth Consulting Services, LLC 1.92% of their portfolio | 237.0k $3.9m | Reduced -45.8k |
| SIMPLEX TRADING, LLC 0.18% of their portfolio | 226.6k $3.7m | Added +88.9k |
| Rock Springs Capital Management LP 0.09% of their portfolio | 223.3k $3.7m | Unchanged |
| MACQUARIE GROUP LTD 0.00% of their portfolio | 208.7k $3.4m | New |
| Candriam S.C.A. 0.02% of their portfolio | 200.0k $3.3m | Unchanged |
| Balyasny Asset Management L.P. 0.01% of their portfolio | 179.7k $3.0m | Reduced -857.9k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 179.1k $2.9m | Reduced -471.9k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 177.9k $2.9m | Added +3.5k |
| GROUP ONE TRADING LLC 0.10% of their portfolio | 175.7k $2.9m | Added +137.2k |
| Knoll Capital Management, LLC 6.45% of their portfolio | 173.9k $2.9m | Unchanged |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 144.7k $2.4m | Reduced -361.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 139.9k $2.3m | Added +28.5k |
| ETF MANAGERS GROUP, LLC 0.11% of their portfolio | 138.2k $2.3m | Added +123.7k |
| PLATINUM INVESTMENT MANAGEMENT LTD 0.07% of their portfolio | 118.7k $2.0m | Unchanged |
| Swiss National Bank 0.00% of their portfolio | 118.3k $1.9m | New |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 110.7k $1.8m | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 105.1k $1.7m | Added +22.7k |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 94.4k $1.6m | Added +37.1k |
| DCF Advisers, LLC 1.03% of their portfolio | 80.7k $1.3m | Reduced -148.3k |
| Walleye Trading LLC 0.03% of their portfolio | 78.3k $1.3m | New |
| PICTON MAHONEY ASSET MANAGEMENT 0.06% of their portfolio | 75.6k $1.2m | Added +17.2k |
| SILVERCREST ASSET MANAGEMENT GROUP LLC 0.01% of their portfolio | 62.5k $1.0m | Unchanged |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio | 54.7k $899.8k | New |
| Bank of New York Mellon Corp 0.00% of their portfolio | 53.3k $876.7k | Reduced -19.8k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio | 52.2k $859.4k | Reduced -34.7k |
| Caption Management, LLC 0.14% of their portfolio | 52.1k $857.1k | Reduced -2.9k |
| SILVERARC CAPITAL MANAGEMENT, LLC 0.29% of their portfolio | 50.5k $831.5k | Reduced -49.9k |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 49.1k $807.9k | New |
| ADVISORY RESEARCH INC 0.07% of their portfolio | 44.2k $727.4k | Added +9.1k |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 42.6k $700.5k | New |
| GSA CAPITAL PARTNERS LLP 0.09% of their portfolio | 41.6k $685.0k | Reduced -1.0k |
| Skandinaviska Enskilda Banken AB (publ) 0.00% of their portfolio | 38.6k $634.0k | Reduced -2.2k |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 38.1k $627.4k | New |
| ClariVest Asset Management LLC 0.03% of their portfolio | 37.4k $615.0k | Reduced -700 |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 35.9k $591.0k | Reduced -98.7k |
| ALPS ADVISORS INC 0.00% of their portfolio | 33.3k $548.2k | Added +6.5k |
| E Fund Management Co., Ltd. 0.04% of their portfolio | 31.3k $515.0k | Added +10.6k |
| Tower Research Capital LLC (TRC) 0.02% of their portfolio | 29.3k $482.0k | Added +171 |
| LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 0.07% of their portfolio | 29.0k $476.6k | New |
| D. E. Shaw & Co., Inc. 0.00% of their portfolio | 27.7k $455.7k | New |
| Arete Wealth Advisors, LLC 0.02% of their portfolio | 24.0k $264.3k | New |
| SG Americas Securities, LLC 0.01% of their portfolio | 23.8k $392.0k | Added +9.8k |
| SeaCrest Wealth Management, LLC 0.06% of their portfolio | 23.5k $387.2k | New |
| Hudson Bay Capital Management LP 0.00% of their portfolio | 20.7k $341.0k | New |
| MML INVESTORS SERVICES, LLC 0.00% of their portfolio | 20.0k $329.0k | Added +5 |
| Lighthouse Investment Partners, LLC 0.06% of their portfolio | 19.5k $321.4k | New |
| ALGERT GLOBAL LLC 0.02% of their portfolio | 18.6k $305.3k | Added +5.3k |
| Belvedere Trading LLC 0.16% of their portfolio | 17.5k $287.7k | New |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 17.3k $284.2k | Unchanged |
| 683 Capital Management, LLC 0.03% of their portfolio | 17.2k $282.6k | New |
| Vahanian & Associates Financial Planning Inc. 0.92% of their portfolio | 17.1k $281.8k | Reduced -250 |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 16.5k $272.0k | Unchanged |
| NinePointTwo Capital LLC 0.11% of their portfolio | 15.9k $262.0k | New |
| MIRABELLA FINANCIAL SERVICES LLP 0.02% of their portfolio | 15.5k $254.4k | New |
| TEACHER RETIREMENT SYSTEM OF TEXAS 0.00% of their portfolio | 14.8k $243.0k | New |
| ARIZONA STATE RETIREMENT SYSTEM 0.00% of their portfolio | 13.8k $227.6k | New |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 13.6k $224.0k | New |
| Quantbot Technologies LP 0.02% of their portfolio | 13.6k $223.6k | Reduced -8.9k |
| Legal & General Group Plc 0.00% of their portfolio | 13.0k $214.6k | Reduced -40.5k |
| VIRTUS ADVISERS, LLC 0.11% of their portfolio | 13.0k $213.7k | New |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 12.6k $208.0k | Reduced -21.9k |
| Man Group plc 0.00% of their portfolio | 12.2k $201.1k | New |
| WealthPLAN Partners, LLC 0.01% of their portfolio | 11.9k $147.7k | First filing |
| WealthPlan Investment Management, LLC 0.01% of their portfolio | 11.9k $157.6k | Reduced -1.2k |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 10.6k $175.1k | New |
| Eagle Ridge Investment Management 0.02% of their portfolio | 10.4k $170.6k | Unchanged |