ALPINE IMMUNE SCIENCES INC NVLS
COM · Common Stock · CUSIP 02083G100
70
institutional holders
39.5m
shares reported held*
$284.0mreported value*
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $7.20. Options: 1 managers hold calls ($0 notional), 2 hold puts ($1.0k).
Biggest calls
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | — | $00 shares |
Biggest puts
| SIMPLEX TRADING, LLC | — | $1.0k200 shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | — | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Holders, Q3 2022
| Manager | Shares | Change |
|---|---|---|
| Decheng Capital Management III (Cayman), LLC 17.51% of their portfolio | 6.7m $48.3m | — |
| RA CAPITAL MANAGEMENT, L.P. 0.67% of their portfolio | 4.4m $31.4m | — |
| ORBIMED ADVISORS LLC 0.55% of their portfolio | 4.1m $29.4m | — |
| GREAT POINT PARTNERS LLC 5.98% of their portfolio | 3.4m $24.8m | — |
| Lynx1 Capital Management LP 19.85% of their portfolio | 3.1m $22.0m | — |
| Frazier Life Sciences Management, L.P. 1.66% of their portfolio | 3.0m $21.5m | — |
| Paradigm Biocapital Advisors LP 2.25% of their portfolio | 2.2m $15.9m | — |
| Omega Fund Management, LLC 5.35% of their portfolio | 2.0m $14.6m | — |
| Commodore Capital LP 1.53% of their portfolio | 1.3m $9.5m | — |
| Octagon Capital Advisors LP 1.52% of their portfolio | 1.2m $8.8m | — |
| Artal Group S.A. 0.45% of their portfolio | 1.2m $8.6m | — |
| BVF INC/IL 0.34% of their portfolio | 1.1m $8.2m | — |
| VANGUARD GROUP INC 0.00% of their portfolio | 1.1m $8.1m | — |
| Avidity Partners Management LP 0.16% of their portfolio | 998.6k $7.2m | — |
| BlackRock Inc. 0.00% of their portfolio | 927.7k $6.7m | — |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 358.7k $2.6m | — |
| STATE STREET CORP 0.00% of their portfolio | 279.0k $2.0m | — |
| TCG Crossover Management, LLC 0.55% of their portfolio | 254.6k $1.8m | — |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 251.5k $1.8m | — |
| SPHERA FUNDS MANAGEMENT LTD. 0.26% of their portfolio | 200.0k $1.4m | — |
| Allspring Global Investments Holdings, LLC 0.00% of their portfolio | 130.2k $937.0k | — |
| NORTHERN TRUST CORP 0.00% of their portfolio | 124.5k $896.0k | — |
| Affinity Asset Advisors, LLC 0.37% of their portfolio | 110.0k $792.0k | — |
| Monashee Investment Management LLC 0.27% of their portfolio | 100.0k $720.0k | — |
| Walleye Capital LLC 0.01% of their portfolio | 71.4k $514.0k | — |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.01% of their portfolio | 70.6k $508.0k | — |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 68.5k $493.0k | — |
| Bank of New York Mellon Corp 0.00% of their portfolio | 64.5k $464.0k | — |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 57.5k $414.0k | — |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 51.4k $370.0k | — |
| Alberta Investment Management Corp 0.00% of their portfolio | 45.9k $331.0k | — |
| CAAS CAPITAL MANAGEMENT LP 0.04% of their portfolio | 45.4k $327.0k | — |
| MARSHALL WACE, LLP 0.00% of their portfolio | 45.1k $323.0k | — |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 39.8k $287.0k | — |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 28.7k $207.0k | — |
| Western Wealth Management, LLC 0.01% of their portfolio | 24.0k $172.0k | — |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 23.9k $172.0k | — |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 21.9k $158.0k | — |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 21.7k $157.0k | — |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 17.8k $128.0k | — |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 12.6k $91.0k | — |
| Hikari Power Ltd 0.01% of their portfolio | 12.4k $90.0k | — |
| MORGAN STANLEY 0.00% of their portfolio | 11.6k $84.0k | — |
| Trexquant Investment LP 0.00% of their portfolio | 10.7k $77.0k | — |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 10.6k $77.0k | — |
| Jump Financial, LLC 0.00% of their portfolio | 10.0k $72.0k | — |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 8.0k $58.0k | — |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 7.4k $53.0k | — |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 6.6k $47.0k | — |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 6.6k $47.3k | — |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 6.2k $44.0k | — |
| BIT Capital GmbH 0.01% of their portfolio | 6.0k $43.2k | — |
| STRS OHIO 0.00% of their portfolio | 5.5k $39.0k | — |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 5.4k $39.0k | — |
| PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 0.00% of their portfolio | 4.9k $35.0k | — |
| Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% of their portfolio | 2.0k $15.0k | — |
| AMALGAMATED BANK 0.00% of their portfolio | 2.0k $15.0k | — |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.6k $12.0k | — |
| Legal & General Group Plc 0.00% of their portfolio | 1.4k $10.0k | — |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 911 $6.0k | — |
| CITIGROUP INC 0.00% of their portfolio | 619 $4.0k | — |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 285 $2.0k | — |
| FMR LLC 0.00% of their portfolio | 202 $1.0k | — |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 190 $1.0k | — |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 129 $0 | — |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 127 $1.0k | — |
| CREDIT SUISSE AG/ 0.00% of their portfolio | 85 $1.0k | — |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 85 $1.0k | — |
| Tradewinds Capital Management, LLC 0.00% of their portfolio | 15 $0 | — |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | — |