ALPHA COGNITION INC ACOG
COM NEW · Common Stock · CUSIP 02074J501
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersGrapevine, TX
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 21.8m as of 2026-08-13, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $7.22.
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q4 2024 | 24 |
| Q1 2025 | 23 |
| Q2 2025 | 27 |
| Q3 2025 | 28 |
| Q4 2025 | 27 |
| Q1 2026 | 25 |
| Q2 2026 | 26 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q1 2025 | 5 | 10 |
| Q2 2025 | 13 | 13 |
| Q3 2025 | 15 | 10 |
| Q4 2025 | 17 | 11 |
| Q1 2026 | 8 | 10 |
| Q2 2026 | 8 | 4 |
Biggest buyers
| Opaleye Management Inc. | Added | +333.5k |
| CANTOR FITZGERALD, L. P. | Added | +29.2k |
| CITADEL ADVISORS LLC | Added | +8.0k |
| TWO SIGMA INVESTMENTS, LP | Added | +2.9k |
| UBS Group AG | Added | +1.0k |
| MORGAN STANLEY | New | +200 |
| JONES FINANCIAL COMPANIES LLLP | Added | +150 |
| HARBOUR INVESTMENTS, INC. | Added | +43 |
Biggest sellers
| Ikarian Capital, LLC | Reduced | -220.0k |
| BOOTHBAY FUND MANAGEMENT, LLC | Reduced | -67.2k |
| SPHERA FUNDS MANAGEMENT LTD. | Reduced | -21.8k |
| ROYAL BANK OF CANADA | Reduced | -557 |
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Opaleye Management Inc. 13G · passive investor +0.9 pts · filed 2026-07-24 | 14.2% |
| AWM Investment Company, Inc. 13G · institution +3.4 pts · filed 2026-02-13 | 9.9% |
| Solas Capital Management, LLC 13G · institution new · filed 2025-02-14 | 8.7% |
| MANCHESTER MANAGEMENT CO LLC 13G · passive investor +2.5 pts · filed 2026-09-23 | 7.4% |
| BESSER JAMES E 13G · passive investor new · filed 2025-01-31 | 6.2% |
| Funicular Funds, LP 13G · passive investor +0.2 pts · filed 2026-02-19 | 5.1% |
Fell to 5% or below in the last year: Ikarian Capital, LLC (4.9%, 2026-02-17)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 3 | $90.0k | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 2 | $377.4k | 1 | $250.0k | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 1 | $20.2k | 0 | — | — |
| Q3 2026 | 1 | $96.2k | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-25 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $113.7k13.4k shares |
| 2026-09-24 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $157.1k18.3k shares |
| 2026-09-16 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $682.4k80.2k shares |
| 2026-09-15 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $28.8k3.4k shares |
| 2026-09-14 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $351.2k40.4k shares |
| 2026-08-21 | Wills Robert James Director | Bought | $96.2k10.0k shares |
| 2026-08-03 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $400.0k50.0k shares |
| 2026-07-31 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $23.0k2.9k shares |
| 2026-07-24 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $1.0k130 shares |
| 2026-07-23 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $388.8k49.8k shares |
| 2026-07-22 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $1.1m140.2k shares |
| 2026-07-22 | Opaleye Management Inc. 10% owner · By Managed Account | Bought | $78.3k10.0k shares |
| 2026-06-26 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $975.0k152.3k shares |
| 2026-06-25 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $1.3k197 shares |
| 2026-06-15 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $27.3k4.5k shares |
| 2026-06-12 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $1.6k273 shares |
| 2026-06-11 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $16.9k2.9k shares |
| 2026-06-10 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $35.2k5.9k shares |
| 2026-06-09 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $148.6k24.9k shares |
| 2026-06-05 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $58.6k10.1k shares |
| 2026-05-29 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $416.4k70.6k shares |
| 2026-05-28 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $11.7k2.0k shares |
| 2026-05-27 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $6.7k1.2k shares |
| 2026-05-21 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $90.9k15.9k shares |
| 2026-05-20 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $49.7k8.4k shares |
| 2026-05-19 | D'Angelo Lauren Chief Operating Officer | Bought | $20.2k3.5k shares |
| 2026-05-18 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $99.0k17.4k shares |
| 2026-05-15 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $97.1k16.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Opaleye Management Inc. 1.89% of their portfolio | 2.9m $20.9m | Added +333.5k |
| Solas Capital Management, LLC 7.45% of their portfolio | 1.9m $13.9m | Unchanged |
| AWM Investment Company, Inc. 1.05% of their portfolio | 1.7m $12.1m | Unchanged |
| Cable Car Capital, LP 0.43% of their portfolio | 1.4m $10.0m | Unchanged |
| Ikarian Capital, LLC 0.99% of their portfolio | 836.3k $6.0m | Reduced -220.0k |
| SPHERA FUNDS MANAGEMENT LTD. 0.56% of their portfolio | 545.8k $3.9m | Reduced -21.8k |
| Alyeska Investment Group, L.P. 0.01% of their portfolio | 365.0k $2.6m | Unchanged |
| Aristides Capital LLC 0.40% of their portfolio | 218.5k $1.6m | Unchanged |
| CANTOR FITZGERALD, L. P. 0.02% of their portfolio | 217.8k $1.6m | Added +29.2k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.03% of their portfolio | 189.1k $1.4m | Reduced -67.2k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 97.5k $704.3k | Added +8.0k |
| VILLERE ST DENIS J & CO LLC 0.06% of their portfolio | 71.2k $513.8k | Unchanged |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 61.6k $444.7k | Unchanged |
| ACT CAPITAL MANAGEMENT, LLC 0.24% of their portfolio | 51.5k $371.8k | Unchanged |
| BERKSHIRE ASSET MANAGEMENT LLC/PA 0.01% of their portfolio | 19.8k $143.1k | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 18.8k $136.0k | Added +2.9k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 12.0k $86.6k | Unchanged |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 10.0k $72.2k | Unchanged |
| NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio | 5.3k $37.7k | Unchanged |
| UBS Group AG 0.00% of their portfolio | 1.5k $10.5k | Added +1.0k |
| Allworth Financial LP 0.00% of their portfolio | 750 $5.4k | Unchanged |
| JONES FINANCIAL COMPANIES LLLP 0.00% of their portfolio | 250 $1.6k | Added +150 |
| MORGAN STANLEY 0.00% of their portfolio | 200 $1.4k | New |
| Steward Partners Investment Advisory, LLC 0.00% of their portfolio | 200 $1.4k | Unchanged |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 122 $1.0k | Reduced -557 |
| HARBOUR INVESTMENTS, INC. 0.00% of their portfolio | 47 $336 | Added +43 |