Vault-13

AKERO THERAPEUTICS INC AKRO

COM · Common Stock · CUSIP 00973Y108

174 institutional holders +16 vs Q4 2023
73,992,79574.0m shares reported held*
$1.9bnreported value*
37 new 74 added 45 reduced 21 sold out net bought ≈ $353.6m (+14.0m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($6.4m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $25.26. Options: 13 managers hold calls ($16.1m notional), 11 hold puts ($20.0m).

Trends to Q1 2024

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 146Q4 22: 162Q1 23: 157Q2 23: 159Q3 23: 183Q4 23: 158Q1 24: 174174Q3 22Q1 23Q3 23Q1 24
Numbers
QuarterHolders
Q3 2022146
Q4 2022162
Q1 2023157
Q2 2023159
Q3 2023183
Q4 2023158
Q1 2024174

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 103 bought or addedQ4 22: 60 cut or sold outQ4 22Q1 23: 75 bought or addedQ1 23: 77 cut or sold outQ1 23Q2 23: 96 bought or addedQ2 23: 64 cut or sold outQ2 23Q3 23: 115 bought or addedQ3 23: 50 cut or sold outQ3 23Q4 23: 81 bought or addedQ4 23: 99 cut or sold outQ4 23Q1 24: 111 bought or addedQ1 24: 66 cut or sold outQ1 24
Numbers
QuarterBought or addedCut or sold out
Q4 202210360
Q1 20237577
Q2 20239664
Q3 202311550
Q4 20238199
Q1 202411166

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$50m$100m$150m$200mQ2 23 calls: $40.8mQ2 23 puts: $60.2mQ2 23P/C 1.47Q3 23 calls: $139.6mQ3 23 puts: $150.8mQ3 23P/C 1.08Q4 23 calls: $42.9mQ4 23 puts: $12.4mQ4 23P/C 0.29Q1 24 calls: $16.1mQ1 24 puts: $20.0mQ1 24P/C 1.24
Numbers
QuarterCallsPutsP/C
Q2 2023$40.8m$60.2m1.47
Q3 2023$139.6m$150.8m1.08
Q4 2023$42.9m$12.4m0.29
Q1 2024$16.1m$20.0m1.24

Biggest buyers

GENERAL ATLANTIC, L.P. Added +3,448,275+3.4m
WELLINGTON MANAGEMENT GROUP LLP Added +2,331,375+2.3m
RTW INVESTMENTS, LP Added +1,839,226+1.8m
JANUS HENDERSON GROUP PLC Added +1,815,569+1.8m
FRED ALGER MANAGEMENT, LLC Added +1,246,069+1.2m
T. Rowe Price Investment Management, Inc. New +1,102,049+1.1m
Redmile Group, LLC Added +749,226+749.2k
BlackRock Inc. Added +712,109+712.1k
VANGUARD GROUP INC Added +584,875+584.9k
Schonfeld Strategic Advisors LLC Added +561,371+561.4k

Biggest sellers

STATE STREET CORP Reduced -1,325,165-1.3m
MORGAN STANLEY Reduced -903,065-903.1k
Commodore Capital LP Sold out -565,000-565.0k
Yiheng Capital Management, L.P. Reduced -489,495-489.5k
ALKEON CAPITAL MANAGEMENT LLC Reduced -437,000-437.0k
Atlas Venture Life Science Advisors, LLC Sold out -359,251-359.3k
Point72 Asset Management, L.P. Reduced -355,199-355.2k
ADAGE CAPITAL PARTNERS GP, L.L.C. Sold out -275,000-275.0k
AMERIPRISE FINANCIAL INC Reduced -238,315-238.3k
Avidity Partners Management LP Sold out -235,000-235.0k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $4.2m165.1k shares
CITADEL ADVISORS LLC Reduced $2.0m77.2k shares
Affinity Asset Advisors, LLC New $1.9m75.0k shares
JPMORGAN CHASE & CO Reduced $1.8m70.0k shares
SIMPLEX TRADING, LLC Reduced $1.6m64.4k shares
GROUP ONE TRADING LLC Reduced $1.3m51.0k shares
Caption Management, LLC Added $1.3m50.0k shares
LMR Partners LLP New $757.8k30.0k shares
JANE STREET GROUP, LLC Reduced $687.1k27.2k shares
Walleye Trading LLC Reduced $558.2k22.1k shares

Biggest puts

Caption Management, LLC New $7.5m296.5k shares
JANE STREET GROUP, LLC Added $4.3m172.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $4.3m170.6k shares
CITADEL ADVISORS LLC Added $1.8m70.5k shares
SIMPLEX TRADING, LLC Added $987.0k39.1k shares
GROUP ONE TRADING LLC Reduced $548.1k21.7k shares
MILLENNIUM MANAGEMENT LLC New $515.3k20.4k shares
Walleye Trading LLC Reduced $37.9k1.5k shares
LMR Partners LLP New $27.8k1.1k shares
Cutler Group LLC / CA Added $2.0k800 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
GENERAL ATLANTIC, L.P. 13G · passive investor filed 2025-05-15 8.4% 6.8m 2025-05-15

Fell to 5% or below in the last year: JANUS HENDERSON GROUP PLC (4.1%, 2026-02-17), RTW INVESTMENTS, LP (0.0%, 2026-02-17), Deep Track Capital, LP (0.0%, 2026-02-13), WELLINGTON MANAGEMENT GROUP LLP (0.0%, 2026-02-10), PRICE T ROWE ASSOCIATES INC /MD/ (4.8%, 2025-11-14)

Holders, Q1 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 JANUS HENDERSON GROUP PLC 0.08% of their portfolio LONDON, X0 6,121,9706.1m $154.6m $154.6m 0.08% Added +1.8m +1,815,569
2 RTW INVESTMENTS, LP 2.03% of their portfolio NEW YORK, NY 5,431,9855.4m $137.2m $137.2m 2.03% Added +1.8m +1,839,226
3 GENERAL ATLANTIC, L.P. 3.07% of their portfolio New York, NY 5,233,9895.2m $132.2m $132.2m 3.07% Added +3.4m +3,448,275
4 WELLINGTON MANAGEMENT GROUP LLP 0.02% of their portfolio Boston, MA 5,213,3645.2m $131.7m $131.7m 0.02% Added +2.3m +2,331,375
5 BlackRock Inc. 0.00% of their portfolio New York, NY 4,892,6164.9m $123.6m $123.6m 0.00% Added +712.1k +712,109
6 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 4,060,4794.1m $102.6m $102.6m 0.01% Added +384.6k +384,555
7 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 3,797,7303.8m $95.9m $95.9m 0.00% Reduced -1.3m -1,325,165
8 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 3,669,9233.7m $92.7m $92.7m 0.00% Added +584.9k +584,875
9 ALKEON CAPITAL MANAGEMENT LLC 0.46% of their portfolio New York, NY 3,327,2203.3m $84.0m $84.0m 0.46% Reduced -437.0k -437,000
10 BAKER BROS. ADVISORS LP 0.86% of their portfolio NEW YORK, NY 2,713,2052.7m $68.5m $68.5m 0.86% Added +344.8k +344,827
11 Redmile Group, LLC 1.72% of their portfolio LARKSPUR, CA 1,858,7021.9m $47.0m $47.0m 1.72% Added +749.2k +749,226
12 Boxer Capital, LLC 2.09% of their portfolio San Diego, CA 1,676,7331.7m $42.4m $42.4m 2.09% Unchanged
13 ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio NASHVILLE, TN 1,621,2621.6m $41.0m $41.0m 0.01% Added +13.6k +13,571
14 Yiheng Capital Management, L.P. 5.20% of their portfolio SAN FRANCISCO, CA 1,434,1791.4m $36.2m $36.2m 5.20% Reduced -489.5k -489,495
15 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,419,3071.4m $35.9m $35.9m 0.00% Added +253.1k +253,062
16 PERCEPTIVE ADVISORS LLC 0.62% of their portfolio NEW YORK, NY 1,387,4711.4m $35.0m $35.0m 0.62% Added +419.7k +419,696
17 FRED ALGER MANAGEMENT, LLC 0.17% of their portfolio NEW YORK, NY 1,336,8811.3m $33.8m $33.8m 0.17% Added +1.2m +1,246,069
18 Rock Springs Capital Management LP 0.83% of their portfolio Baltimore, MD 1,299,8881.3m $32.8m $32.8m 0.83% Added +218.8k +218,824
19 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 1,211,5891.2m $30.6m $30.6m 0.00% Reduced -903.1k -903,065
20 T. Rowe Price Investment Management, Inc. 0.02% of their portfolio BALTIMORE, MD 1,102,0491.1m $27.8m $27.8m 0.02% New
21 Logos Global Management LP 2.13% of their portfolio San Francisco, CA 800,000800.0k $20.2m $20.2m 2.13% Unchanged
22 MILLENNIUM MANAGEMENT LLC 0.02% of their portfolio NEW YORK, NY 792,575792.6k $20.0m $20.0m 0.02% Added +535.4k +535,381
23 Schonfeld Strategic Advisors LLC 0.14% of their portfolio NEW YORK, NY 695,723695.7k $17.6m $17.6m 0.14% Added +561.4k +561,371
24 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 650,798650.8k $16.4m $16.4m 0.00% Added +345.0k +345,042
25 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 597,688597.7k $15.1m $15.1m 0.00% Added +57.0k +57,003
26 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 589,852589.9k $14.9m $14.9m 0.00% Reduced -23.4k -23,423
27 EMERALD ADVISERS, LLC 0.55% of their portfolio LEOLA, PA 538,873538.9k $13.6m $13.6m 0.55% Added +399.2k +399,183
28 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 518,286518.3k $13.1m $13.1m 0.00% Added +92.7k +92,741
29 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 425,871425.9k $10.8m $10.8m 0.00% Reduced -63.8k -63,770
30 EMERALD MUTUAL FUND ADVISERS TRUST 0.56% of their portfolio LEOLA, PA 424,901424.9k $10.7m $10.7m 0.56% Added +308.8k +308,820
31 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 419,660419.7k $10.6m $10.6m 0.01% Reduced -65.4k -65,365
32 D. E. Shaw & Co., Inc. 0.01% of their portfolio New York, NY 407,125407.1k $10.3m $10.3m 0.01% Added +196.2k +196,165
33 SILVERARC CAPITAL MANAGEMENT, LLC 2.83% of their portfolio BOSTON, MA 399,949399.9k $10.1m $10.1m 2.83% Added +150.7k +150,695
34 University of Wisconsin Foundation 10.62% of their portfolio MADISON, WI 372,575372.6k $9.4m $9.4m 10.62% Unchanged
35 Octagon Capital Advisors LP 1.04% of their portfolio NEW YORK, NY 340,000340.0k $8.6m $8.6m 1.04% New
36 MPM BIOIMPACT LLC 1.36% of their portfolio BOSTON, MA 332,924332.9k $8.4m $8.4m 1.36% New
37 Long Focus Capital Management, LLC 0.96% of their portfolio SAN JUAN, PR 328,604328.6k $8.3m $8.3m 0.96% Reduced -181.4k -181,396
38 Propel Bio Management, LLC 4.82% of their portfolio Los Angeles, CA 327,752327.8k $8.3m $8.3m 4.82% Added +227.7k +227,700
39 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 326,755326.8k $8.3m $8.3m 0.00% Added +136.5k +136,544
40 Artisan Partners Limited Partnership 0.01% of their portfolio Milwaukee, WI 303,920303.9k $7.7m $7.7m 0.01% Unchanged
41 Rafferty Asset Management, LLC 0.03% of their portfolio New York, NY 294,113294.1k $7.4m $7.4m 0.03% Reduced -157.7k -157,719
42 Point72 Asset Management, L.P. 0.02% of their portfolio STAMFORD, CT 289,106289.1k $7.3m $7.3m 0.02% Reduced -355.2k -355,199
43 CITIGROUP INC 0.01% of their portfolio NEW YORK, NY 255,434255.4k $6.5m $6.5m 0.01% Added +67.0k +66,982
44 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 250,075250.1k $6.3m $6.3m 0.01% Reduced -5.5k -5,474
45 Simplify Asset Management Inc. 0.59% of their portfolio Las Vegas, NV 245,676245.7k $6.2m $6.2m 0.59% Added +185.9k +185,899
46 Candriam S.C.A. 0.04% of their portfolio STRASSEN, N4 240,000240.0k $6.1m $6.1m 0.04% Added +56.0k +56,000
47 Ensign Peak Advisors, Inc 0.01% of their portfolio SALT LAKE CITY, UT 232,544232.5k $5.9m $5.9m 0.01% Reduced -720 -720
48 UBS Group AG 0.00% of their portfolio ZURICH, V8 208,001208.0k $5.3m $5.3m 0.00% Reduced -58.4k -58,385
49 Aberdeen Group plc 0.01% of their portfolio EDINBURGH, X0 199,237199.2k $5.0m $5.0m 0.01% Added +127.7k +127,695
50 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 189,246189.2k $4.8m $4.8m 0.00% Added +11.5k +11,451
51 SCHRODER INVESTMENT MANAGEMENT GROUP 0.01% of their portfolio London, X0 170,956171.0k $4.3m $4.3m 0.01% New
52 SPHERA FUNDS MANAGEMENT LTD. 0.66% of their portfolio TEL AVIV, L3 160,445160.4k $4.1m $4.1m 0.66% New
53 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 144,863144.9k $3.7m $3.7m 0.00% Added +12.7k +12,722
54 Woodline Partners LP 0.03% of their portfolio San Francisco, CA 128,441128.4k $3.2m $3.2m 0.03% New
55 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 124,992125.0k $3.2m $3.2m 0.00% Added +30.8k +30,790
56 PDT Partners, LLC 0.30% of their portfolio New York, NY 124,448124.4k $3.1m $3.1m 0.30% New
57 MARSHALL WACE, LLP 0.01% of their portfolio LONDON, X0 120,674120.7k $3.0m $3.0m 0.01% New
58 Jump Financial, LLC 0.07% of their portfolio Chicago, IL 107,275107.3k $2.7m $2.7m 0.07% New
59 Swiss National Bank 0.00% of their portfolio ZURICH, V8 105,000105.0k $2.7m $2.7m 0.00% Added +17.4k +17,400
60 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 104,120104.1k $2.6m $2.6m 0.00% Added +82.4k +82,403
61 Connor, Clark & Lunn Investment Management Ltd. 0.01% of their portfolio VANCOUVER, A1 102,602102.6k $2.6m $2.6m 0.01% Added +92.6k +92,587
62 TWINBEECH CAPITAL LP 0.05% of their portfolio PURCHASE, NY 98,98299.0k $2.5m $2.5m 0.05% New
63 ALGERT GLOBAL LLC 0.09% of their portfolio SAN FRANCISCO, CA 87,42387.4k $2.2m $2.2m 0.09% Added +38.9k +38,873
64 CAPSTONE INVESTMENT ADVISORS, LLC 0.04% of their portfolio NEW YORK, NY 87,29287.3k $2.2m $2.2m 0.04% New
65 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 84,97785.0k $2.1m $2.1m 0.00% Added +14.0k +13,952
66 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 82,39882.4k $2.1m $2.1m 0.00% Added +11.7k +11,699
67 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 70,68170.7k $1.8m $1.8m 0.00% Reduced -175.6k -175,593
68 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 59,29459.3k $1.5m $1.5m 0.00% Reduced -152.9k -152,918
69 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 54,18554.2k $1.4m $1.4m 0.00% Added +6.1k +6,113
70 Entropy Technologies, LP 0.14% of their portfolio NEW YORK, NY 52,77552.8k $1.3m $1.3m 0.14% Added +7.9k +7,927
71 Legal & General Group Plc 0.00% of their portfolio London, X0 49,92749.9k $1.3m $1.3m 0.00% Added +6.8k +6,790
72 Erste Asset Management GmbH 0.02% of their portfolio VIENNA, C4 47,00047.0k $1.1m $1.1m 0.02% Unchanged
73 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 46,54746.5k $1.2m $1.2m 0.00% Added +6.2k +6,163
74 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 46,53946.5k $1.2m $1.2m 0.00% Unchanged
75 PROFUND ADVISORS LLC 0.05% of their portfolio BETHESDA, MD 45,87045.9k $1.2m $1.2m 0.05% Reduced -26.7k -26,674
76 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 45,43645.4k $1.1m $1.1m 0.00% Added +24.5k +24,493
77 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 44,28744.3k $1.1m $1.1m 0.00% New
78 SEVEN EIGHT CAPITAL, LP 0.11% of their portfolio New York, NY 40,38440.4k $1.0m $1.0m 0.11% Reduced -22.1k -22,080
79 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 39,85139.9k $1.0m $1.0m 0.00% Added +11.4k +11,400
80 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 39,70939.7k $1.0m $1.0m 0.01% Added +2.5k +2,477
81 TUDOR INVESTMENT CORP ET AL 0.01% of their portfolio STAMFORD, CT 36,19536.2k $914.3k $914.3k 0.01% New
82 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 34,73834.7k $877.5k $877.5k 0.00% Added +193 +193
83 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 32,78132.8k $828.0k $828.0k 0.00% Reduced -33.2k -33,152
84 MetLife Investment Management, LLC 0.01% of their portfolio Whippany, NJ 32,24032.2k $814.4k $814.4k 0.01% Added +5.2k +5,245
85 OMERS ADMINISTRATION Corp 0.01% of their portfolio TORONTO, A6 32,10032.1k $810.8k $810.8k 0.01% New
86 NEOS Investment Management LLC 0.05% of their portfolio Westport, CT 31,52931.5k $796.4k $796.4k 0.05% New
87 AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio New York, NY 30,32630.3k $766.0k $766.0k 0.00% Added +4.8k +4,812
88 TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 0.01% of their portfolio FRANKFORT, KY 28,52128.5k $720.0k $720.0k 0.01% Added +6.6k +6,590
89 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 25,65825.7k $845.3k $845.3k 0.00% Reduced -14.2k -14,227
90 Chicago Partners Investment Group LLC 0.02% of their portfolio CHICAGO, IL 25,20025.2k $529.2k $529.2k 0.02% Unchanged
91 GUGGENHEIM CAPITAL LLC 0.00% of their portfolio CHICAGO, IL 25,03725.0k $632.4k $632.4k 0.00% Reduced -6.2k -6,185
92 Atle Fund Management AB 0.38% of their portfolio STOCKHOLM, V7 24,43224.4k $617.2k $617.2k 0.38% Added +9.0k +9,000
93 CAPITAL FUND MANAGEMENT S.A. 0.01% of their portfolio PARIS, I0 21,32321.3k $538.6k $538.6k 0.01% Reduced -1.9k -1,896
94 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 20,12620.1k $508.4k $508.4k 0.00% Added +5.8k +5,763
95 DekaBank Deutsche Girozentrale 0.00% of their portfolio FRANKFURT, 2M 20,00020.0k $488.0k $488.0k 0.00% Reduced -7.6k -7,600
96 Aquatic Capital Management LLC 0.02% of their portfolio CHICAGO, IL 19,80019.8k $500.1k $500.1k 0.02% New
97 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 19,69319.7k $497.4k $497.4k 0.00% Reduced -613 -613
98 Engineers Gate Manager LP 0.01% of their portfolio NEW YORK, NY 17,75917.8k $448.6k $448.6k 0.01% New
99 LMR Partners LLP 0.01% of their portfolio LONDON, X0 17,60017.6k $444.6k $444.6k 0.01% New
100 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 17,46617.5k $441.0k $441.0k 0.00% Reduced -12.9k -12,936