Vault-13

AKERO THERAPEUTICS INC AKRO

COM · Common Stock · CUSIP 00973Y108

158 institutional holders -25 vs Q3 2023
60,185,04760.2m shares reported held*
$1.4bnreported value*
22 new 59 added 45 reduced 54 sold out net bought ≈ $44.8m (+2.2m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.5m this quarter). Holder counts are more reliable. Implied quarter-end price ≈ $23.35. Options: 16 managers hold calls ($42.9m notional), 10 hold puts ($12.4m).

Trends to Q4 2023

Institutional holders

Managers reporting a position, each quarter

0100200Q3 22: 146Q4 22: 162Q1 23: 157Q2 23: 159Q3 23: 183Q4 23: 158158Q3 22Q4 22Q1 23Q2 23Q3 23Q4 23
Numbers
QuarterHolders
Q3 2022146
Q4 2022162
Q1 2023157
Q2 2023159
Q3 2023183
Q4 2023158

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q4 22: 103 bought or addedQ4 22: 60 cut or sold outQ4 22Q1 23: 75 bought or addedQ1 23: 77 cut or sold outQ1 23Q2 23: 96 bought or addedQ2 23: 64 cut or sold outQ2 23Q3 23: 115 bought or addedQ3 23: 50 cut or sold outQ3 23Q4 23: 81 bought or addedQ4 23: 99 cut or sold outQ4 23
Numbers
QuarterBought or addedCut or sold out
Q4 202210360
Q1 20237577
Q2 20239664
Q3 202311550
Q4 20238199

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$50m$100m$150m$200mQ1 23 calls: $25.3mQ1 23 puts: $16.9mQ1 23P/C 0.67Q2 23 calls: $40.8mQ2 23 puts: $60.2mQ2 23P/C 1.47Q3 23 calls: $139.6mQ3 23 puts: $150.8mQ3 23P/C 1.08Q4 23 calls: $42.9mQ4 23 puts: $12.4mQ4 23P/C 0.29
Numbers
QuarterCallsPutsP/C
Q1 2023$25.3m$16.9m0.67
Q2 2023$40.8m$60.2m1.47
Q3 2023$139.6m$150.8m1.08
Q4 2023$42.9m$12.4m0.29

Biggest buyers

RTW INVESTMENTS, LP New +3,592,759+3.6m
STATE STREET CORP Added +2,617,047+2.6m
WELLINGTON MANAGEMENT GROUP LLP Added +2,053,028+2.1m
MORGAN STANLEY Added +1,674,918+1.7m
Yiheng Capital Management, L.P. Added +702,000+702.0k
Point72 Asset Management, L.P. Added +605,705+605.7k
Long Focus Capital Management, LLC Added +366,000+366.0k
ALLIANCEBERNSTEIN L.P. Added +325,981+326.0k
BANK OF AMERICA CORP /DE/ Added +294,756+294.8k
GOLDMAN SACHS GROUP INC Added +282,190+282.2k

Biggest sellers

FMR LLC Reduced -2,747,276-2.7m
ADAGE CAPITAL PARTNERS GP, L.L.C. Reduced -1,668,009-1.7m
LORD, ABBETT & CO. LLC Sold out -1,558,252-1.6m
Redmile Group, LLC Reduced -660,208-660.2k
PERCEPTIVE ADVISORS LLC Reduced -651,650-651.6k
Avoro Capital Advisors LLC Sold out -555,555-555.6k
EVENTIDE ASSET MANAGEMENT, LLC Sold out -513,876-513.9k
Avidity Partners Management LP Reduced -504,100-504.1k
JPMORGAN CHASE & CO Reduced -408,822-408.8k
Pictet Asset Management Holding SA Sold out -399,285-399.3k

Biggest calls

SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $14.4m617.7k shares
Holocene Advisors, LP Added $14.3m612.0k shares
GROUP ONE TRADING LLC Added $2.9m124.6k shares
CITADEL ADVISORS LLC Added $2.3m98.8k shares
JPMORGAN CHASE & CO Reduced $2.0m84.2k shares
JANE STREET GROUP, LLC Reduced $1.9m81.8k shares
SIMPLEX TRADING, LLC Added $1.8m78.0k shares
MOORE CAPITAL MANAGEMENT, LP Reduced $875.6k37.5k shares
Caption Management, LLC Reduced $639.8k27.4k shares
Walleye Trading LLC Added $572.1k24.5k shares

Biggest puts

JANE STREET GROUP, LLC Added $3.9m168.3k shares
GROUP ONE TRADING LLC Added $3.8m162.3k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $2.4m103.3k shares
CITADEL ADVISORS LLC Added $1.3m54.3k shares
Walleye Capital LLC New $476.3k20.4k shares
SIMPLEX TRADING, LLC Reduced $219.0k9.4k shares
CITIGROUP INC Unchanged $158.8k6.8k shares
Walleye Trading LLC Reduced $135.4k5.8k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares
Cutler Group LLC / CA New $0100 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
GENERAL ATLANTIC, L.P. 13G · passive investor filed 2025-05-15 8.4% 6.8m 2025-05-15

Fell to 5% or below in the last year: JANUS HENDERSON GROUP PLC (4.1%, 2026-02-17), RTW INVESTMENTS, LP (0.0%, 2026-02-17), Deep Track Capital, LP (0.0%, 2026-02-13), WELLINGTON MANAGEMENT GROUP LLP (0.0%, 2026-02-10), PRICE T ROWE ASSOCIATES INC /MD/ (4.8%, 2025-11-14)

Holders, Q4 2023

#ManagerLocationShares Value% of their portfolioChangeShares change
1 STATE STREET CORP 0.01% of their portfolio BOSTON, MA 5,122,8955.1m $119.6m $119.6m 0.01% Added +2.6m +2,617,047
2 JANUS HENDERSON GROUP PLC 0.06% of their portfolio LONDON, X0 4,306,4014.3m $100.6m $100.6m 0.06% Reduced -180.3k -180,325
3 BlackRock Inc. 0.00% of their portfolio New York, NY 4,180,5074.2m $97.6m $97.6m 0.00% Added +203.2k +203,187
4 ALKEON CAPITAL MANAGEMENT LLC 0.58% of their portfolio New York, NY 3,764,2203.8m $87.9m $87.9m 0.58% Reduced -3.2k -3,160
5 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 3,675,9243.7m $85.8m $85.8m 0.01% Reduced -134.3k -134,270
6 RTW INVESTMENTS, LP 1.31% of their portfolio NEW YORK, NY 3,592,7593.6m $83.9m $83.9m 1.31% New
7 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 3,085,0483.1m $72.0m $72.0m 0.00% Added +72.9k +72,866
8 WELLINGTON MANAGEMENT GROUP LLP 0.01% of their portfolio Boston, MA 2,881,9892.9m $67.3m $67.3m 0.01% Added +2.1m +2,053,028
9 BAKER BROS. ADVISORS LP 0.63% of their portfolio NEW YORK, NY 2,368,3782.4m $55.3m $55.3m 0.63% Unchanged
10 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 2,114,6542.1m $49.4m $49.4m 0.00% Added +1.7m +1,674,918
11 Yiheng Capital Management, L.P. 5.56% of their portfolio SAN FRANCISCO, CA 1,923,6741.9m $44.9m $44.9m 5.56% Added +702.0k +702,000
12 GENERAL ATLANTIC, L.P. 0.60% of their portfolio New York, NY 1,785,7141.8m $41.7m $41.7m 0.60% Unchanged
13 Boxer Capital, LLC 1.95% of their portfolio San Diego, CA 1,676,7331.7m $39.2m $39.2m 1.95% Unchanged
14 ALLIANCEBERNSTEIN L.P. 0.01% of their portfolio NASHVILLE, TN 1,607,6911.6m $37.5m $37.5m 0.01% Added +326.0k +325,981
15 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,166,2451.2m $27.2m $27.2m 0.00% Added +62.9k +62,939
16 Redmile Group, LLC 0.93% of their portfolio LARKSPUR, CA 1,109,4761.1m $25.9m $25.9m 0.93% Reduced -660.2k -660,208
17 Rock Springs Capital Management LP 0.62% of their portfolio Baltimore, MD 1,081,0641.1m $25.2m $25.2m 0.62% Reduced -338.1k -338,086
18 PERCEPTIVE ADVISORS LLC 0.51% of their portfolio NEW YORK, NY 967,775967.8k $22.6m $22.6m 0.51% Reduced -651.6k -651,650
19 Logos Global Management LP 2.08% of their portfolio San Francisco, CA 800,000800.0k $18.7m $18.7m 2.08% Added +200.0k +200,000
20 Point72 Asset Management, L.P. 0.05% of their portfolio STAMFORD, CT 644,305644.3k $15.0m $15.0m 0.05% Added +605.7k +605,705
21 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 613,275613.3k $14.3m $14.3m 0.00% Added +282.2k +282,190
22 Commodore Capital LP 1.15% of their portfolio NEW YORK, NY 565,000565.0k $13.2m $13.2m 1.15% Unchanged
23 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 540,685540.7k $12.6m $12.6m 0.00% Added +2.7k +2,662
24 Long Focus Capital Management, LLC 1.54% of their portfolio SAN JUAN, PR 510,000510.0k $11.9m $11.9m 1.54% Added +366.0k +366,000
25 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 489,641489.6k $11.4m $11.4m 0.00% Added +294.8k +294,756
26 CITADEL ADVISORS LLC 0.01% of their portfolio MIAMI, FL 485,025485.0k $11.3m $11.3m 0.01% Added +182.4k +182,438
27 Rafferty Asset Management, LLC 0.04% of their portfolio New York, NY 451,832451.8k $10.6m $10.6m 0.04% Added +268.3k +268,335
28 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 425,545425.5k $9.9m $9.9m 0.00% Added +6.1k +6,115
29 University of Wisconsin Foundation 14.48% of their portfolio MADISON, WI 372,575372.6k $8.7m $8.7m 14.48% Added +268.8k +268,759
30 Atlas Venture Life Science Advisors, LLC 1.00% of their portfolio CAMBRIDGE, MA 359,251359.3k $8.4m $8.4m 1.00% Unchanged
31 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 305,756305.8k $7.1m $7.1m 0.00% Reduced -408.8k -408,822
32 Artisan Partners Limited Partnership 0.01% of their portfolio Milwaukee, WI 303,920303.9k $7.1m $7.1m 0.01% Reduced -7.1k -7,116
33 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.01% of their portfolio Boston, MA 275,000275.0k $6.4m $6.4m 0.01% Reduced -1.7m -1,668,009
34 UBS Group AG 0.00% of their portfolio ZURICH, V8 266,386266.4k $6.2m $6.2m 0.00% Added +208.0k +207,983
35 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 257,194257.2k $6.0m $6.0m 0.01% New
36 JANE STREET GROUP, LLC 0.01% of their portfolio NEW YORK, NY 255,549255.5k $6.0m $6.0m 0.01% Added +79.5k +79,513
37 SILVERARC CAPITAL MANAGEMENT, LLC 1.79% of their portfolio BOSTON, MA 249,254249.3k $5.8m $5.8m 1.79% Added +217.9k +217,918
38 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 246,893246.9k $5.8m $5.8m 0.00% Added +226.3k +226,255
39 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 246,274246.3k $5.8m $5.8m 0.00% Added +114.8k +114,828
40 Avidity Partners Management LP 0.21% of their portfolio DALLAS, TX 235,000235.0k $5.5m $5.5m 0.21% Reduced -504.1k -504,100
41 Ensign Peak Advisors, Inc 0.01% of their portfolio SALT LAKE CITY, UT 233,264233.3k $5.4m $5.4m 0.01% Added +650 +650
42 BNP PARIBAS FINANCIAL MARKETS 0.01% of their portfolio PARIS, I0 212,212212.2k $5.0m $5.0m 0.01% Added +152.7k +152,691
43 D. E. Shaw & Co., Inc. 0.01% of their portfolio New York, NY 210,960211.0k $4.9m $4.9m 0.01% Added +74.1k +74,062
44 Balyasny Asset Management L.P. 0.01% of their portfolio Chicago, IL 198,271198.3k $4.6m $4.6m 0.01% Added +159.0k +158,988
45 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 190,211190.2k $4.4m $4.4m 0.00% Added +79.6k +79,612
46 CITIGROUP INC 0.01% of their portfolio NEW YORK, NY 188,452188.5k $4.4m $4.4m 0.01% Added +92.0k +91,962
47 Candriam S.C.A. 0.03% of their portfolio STRASSEN, N4 184,000184.0k $4.3m $4.3m 0.03% Added +84.0k +84,000
48 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 177,795177.8k $4.2m $4.2m 0.00% Reduced -322.4k -322,450
49 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio JUPITER, FL 174,222174.2k $4.1m $4.1m 0.02% New
50 EMERALD ADVISERS, LLC 0.14% of their portfolio LEOLA, PA 139,690139.7k $3.3m $3.3m 0.14% New
51 Qube Research & Technologies Ltd 0.01% of their portfolio LONDON, X0 136,828136.8k $3.2m $3.2m 0.01% New
52 Schonfeld Strategic Advisors LLC 0.03% of their portfolio NEW YORK, NY 134,352134.4k $3.1m $3.1m 0.03% Reduced -77.7k -77,656
53 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 132,141132.1k $3.1m $3.1m 0.00% Added +658 +658
54 Walleye Capital LLC 0.04% of their portfolio NEW YORK, NY 130,017130.0k $3.0m $3.0m 0.04% New
55 EMERALD MUTUAL FUND ADVISERS TRUST 0.14% of their portfolio LEOLA, PA 116,081116.1k $2.7m $2.7m 0.14% New
56 Walleye Trading LLC 0.04% of their portfolio NEW YORK, NY 116,054116.1k $2.7m $2.7m 0.04% Added +491 +491
57 Propel Bio Management, LLC 1.94% of their portfolio Los Angeles, CA 100,052100.1k $2.3m $2.3m 1.94% First filing
58 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 94,20294.2k $2.2m $2.2m 0.00% Reduced -31.9k -31,890
59 FRED ALGER MANAGEMENT, LLC 0.01% of their portfolio NEW YORK, NY 90,81290.8k $2.1m $2.1m 0.01% Reduced -350.3k -350,274
60 Swiss National Bank 0.00% of their portfolio ZURICH, V8 87,60087.6k $2.0m $2.0m 0.00% Reduced -9.7k -9,700
61 Atika Capital Management LLC 0.27% of their portfolio NEW YORK, NY 79,93579.9k $1.9m $1.9m 0.27% New
62 Squarepoint Ops LLC 0.01% of their portfolio NEW YORK, NY 75,14975.1k $1.8m $1.8m 0.01% Added +39.6k +39,558
63 PROFUND ADVISORS LLC 0.07% of their portfolio BETHESDA, MD 72,54472.5k $1.7m $1.7m 0.07% Added +41.3k +41,322
64 Aberdeen Group plc 0.00% of their portfolio EDINBURGH, X0 71,54271.5k $1.7m $1.7m 0.00% New
65 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 71,02571.0k $1.7m $1.7m 0.00% Reduced -5.6k -5,588
66 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 70,69970.7k $1.7m $1.7m 0.00% Reduced -85 -85
67 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 65,93365.9k $1.5m $1.5m 0.00% Added +14.3k +14,347
68 SEVEN EIGHT CAPITAL, LP 0.17% of their portfolio New York, NY 62,46462.5k $1.5m $1.5m 0.17% New
69 Simplify Asset Management Inc. 0.22% of their portfolio Las Vegas, NV 59,77759.8k $1.4m $1.4m 0.22% Unchanged
70 HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND 0.00% of their portfolio TORONTO, A6 54,00054.0k $1.3m $1.3m 0.00% Added +42.0k +42,000
71 ALGERT GLOBAL LLC 0.05% of their portfolio SAN FRANCISCO, CA 48,55048.5k $1.1m $1.1m 0.05% Added +37.8k +37,776
72 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 48,07248.1k $1.1m $1.1m 0.00% Reduced -2.4k -2,428
73 ExodusPoint Capital Management, LP 0.01% of their portfolio NEW YORK, NY 48,04848.0k $1.1m $1.1m 0.01% New
74 Erste Asset Management GmbH 0.02% of their portfolio VIENNA, C4 47,00047.0k $1.1m $1.1m 0.02% New
75 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 46,53946.5k $1.1m $1.1m 0.00% Unchanged
76 Atom Investors LP 0.19% of their portfolio AUSTIN, TX 45,69445.7k $1.1m $1.1m 0.19% Added +26.6k +26,614
77 Entropy Technologies, LP 0.19% of their portfolio NEW YORK, NY 44,84844.8k $1.0m $1.0m 0.19% First filing
78 Legal & General Group Plc 0.00% of their portfolio London, X0 43,13743.1k $1.0m $1.0m 0.00% Reduced -112 -112
79 CREDIT SUISSE AG/ 0.00% of their portfolio ZURICH, V8 40,38440.4k $943.0k $943.0k 0.00% Reduced -2.8k -2,811
80 Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio SEOUL, M5 39,88539.9k $931.3k $931.3k 0.00% Added +9.6k +9,567
81 GROUP ONE TRADING LLC 0.03% of their portfolio CHICAGO, IL 37,87137.9k $884.3k $884.3k 0.03% Added +12.9k +12,853
82 ALPS ADVISORS INC 0.01% of their portfolio Denver, CO 37,23237.2k $869.4k $869.4k 0.01% Reduced -3.8k -3,776
83 HRT FINANCIAL LP 0.01% of their portfolio NEW YORK, NY 36,63936.6k $855.0k $855.0k 0.01% New
84 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 34,54534.5k $806.6k $806.6k 0.00% Added +1.2k +1,214
85 GUGGENHEIM CAPITAL LLC 0.01% of their portfolio CHICAGO, IL 31,22231.2k $729.0k $729.0k 0.01% New
86 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 30,40230.4k $710.0k $710.0k 0.00% Added +11.7k +11,737
87 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 28,45128.5k $664.3k $664.3k 0.00% Reduced -224.1k -224,102
88 DekaBank Deutsche Girozentrale 0.00% of their portfolio FRANKFURT, 2M 27,60027.6k $659.0k $659.0k 0.00% Unchanged
89 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 26,99527.0k $630.3k $630.3k 0.00% Unchanged
90 AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio New York, NY 25,51425.5k $595.8k $595.8k 0.00% Reduced -103 -103
91 Chicago Partners Investment Group LLC 0.03% of their portfolio CHICAGO, IL 25,20025.2k $551.1k $551.1k 0.03% Unchanged
92 E Fund Management Co., Ltd. 0.04% of their portfolio GUANGZHOU, F4 24,17224.2k $564.4k $564.4k 0.04% Added +14.7k +14,744
93 CAPITAL FUND MANAGEMENT S.A. 0.01% of their portfolio PARIS, I0 23,21923.2k $542.2k $542.2k 0.01% New
94 TEACHERS RETIREMENT SYSTEM OF THE STATE OF KENTUCKY 0.00% of their portfolio FRANKFORT, KY 21,93121.9k $512.0k $512.0k 0.00% New
95 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 21,79921.8k $509.0k $509.0k 0.00% Reduced -1.1k -1,093
96 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 21,71721.7k $507.1k $507.1k 0.00% Reduced -329.2k -329,192
97 DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio AUSTIN, TX 20,94320.9k $489.0k $489.0k 0.00% Reduced -81.5k -81,477
98 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 20,30620.3k $474.1k $474.1k 0.00% Reduced -13.3k -13,305
99 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 16,76716.8k $391.5k $391.5k 0.00% Added +5.9k +5,868
100 ADAR1 Capital Management, LLC 0.17% of their portfolio AUSTIN, TX 16,00016.0k $373.6k $373.6k 0.17% First filing