AKEBIA THERAPEUTICS INC AKBA
COM · Common Stock · CUSIP 00972D105 · ISIN US00972D1054
Company in Cambridge, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWaltham, MA
- Founded2007
- Websiteakebia.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($215.4k this quarter). Holder counts are more reliable. Shares outstanding: 268.3m as of 2026-05-04, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.39. Options: 6 managers hold calls ($932.8k notional), 5 hold puts ($557.0k).
Trends to Q1 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 91 |
| Q4 2022 | 75 |
| Q1 2023 | 66 |
| Q2 2023 | 80 |
| Q3 2023 | 77 |
| Q4 2023 | 88 |
| Q1 2024 | 115 |
| Q2 2024 | 104 |
| Q3 2024 | 115 |
| Q4 2024 | 123 |
| Q1 2025 | 145 |
| Q2 2025 | 159 |
| Q3 2025 | 177 |
| Q4 2025 | 166 |
| Q1 2026 | 171 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q2 2024 | 53 | 54 |
| Q3 2024 | 55 | 40 |
| Q4 2024 | 67 | 34 |
| Q1 2025 | 90 | 31 |
| Q2 2025 | 109 | 41 |
| Q3 2025 | 105 | 57 |
| Q4 2025 | 84 | 80 |
| Q1 2026 | 70 | 81 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2025 | $2.2m | $1.5m | 0.69 |
| Q3 2025 | $2.1m | $1.2m | 0.57 |
| Q4 2025 | $975.8k | $683.9k | 0.70 |
| Q1 2026 | $932.8k | $557.0k | 0.60 |
Biggest buyers
| TWO SIGMA INVESTMENTS, LP | Added | +1.2m |
| AQR CAPITAL MANAGEMENT LLC | Added | +1.1m |
| JANE STREET GROUP, LLC | Added | +765.1k |
| MILLENNIUM MANAGEMENT LLC | Added | +731.2k |
| LOS ANGELES CAPITAL MANAGEMENT LLC | Added | +571.7k |
| BANK OF AMERICA CORP /DE/ | Added | +506.0k |
| CITIGROUP INC | Added | +418.4k |
| Voleon Capital Management LP | Added | +404.4k |
| MANGROVE PARTNERS IM, LLC | New | +376.0k |
| VIRTUS ADVISERS, LLC | New | +308.0k |
Biggest sellers
| CITADEL ADVISORS LLC | Reduced | -3.3m |
| STATE STREET CORP | Reduced | -2.1m |
| RENAISSANCE TECHNOLOGIES LLC | Reduced | -1.8m |
| FEDERATED HERMES, INC. | Sold out | -1.3m |
| GOLDMAN SACHS GROUP INC | Reduced | -1.1m |
| FIRST TRUST ADVISORS LP | Sold out | -941.7k |
| ACADIAN ASSET MANAGEMENT LLC | Reduced | -822.7k |
| Squarepoint Ops LLC | Reduced | -800.2k |
| BARCLAYS PLC | Reduced | -781.3k |
| NORDEA INVESTMENT MANAGEMENT AB | Sold out | -752.1k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $274.2k197.3k shares |
| CITADEL ADVISORS LLC | Added | $247.7k178.2k shares |
| JANE STREET GROUP, LLC | Added | $183.3k131.9k shares |
| SIMPLEX TRADING, LLC | Reduced | $112.7k81.1k shares |
| GROUP ONE TRADING LLC | Reduced | $99.7k71.7k shares |
| TUDOR INVESTMENT CORP ET AL | Unchanged | $15.2k10.9k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $258.1k185.7k shares |
| CITADEL ADVISORS LLC | Reduced | $219.8k158.1k shares |
| GROUP ONE TRADING LLC | Added | $68.1k49.0k shares |
| UBS Group AG | New | $8.3k6.0k shares |
| SIMPLEX TRADING, LLC | Reduced | $2.6k1.9k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BlackRock, Inc. 13G · institution +1.1 pts · filed 2026-01-21 | 7.2% |
Fell to 5% or below in the last year: STATE STREET CORP (4.3%, 2026-05-12), VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales in Q1 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2024 | 0 | — | 2 | $59.0k | $59.0k |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 4 | $687.2k | $687.2k |
| Q2 2025 | 0 | — | 2 | $258.8k | $258.8k |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 1 | $86.6k | 6 | $900.8k | $900.8k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-03-04 | Butler John P. CEO and President, director | Bought | $86.6k69.3k shares |
| 2026-02-02 | Butler John P. CEO and President, director | Sold plan | $474.4k341.3k shares |
| 2026-02-02 | Grund Nicholas Chief Commercial Officer | Sold plan | $117.9k84.8k shares |
| 2026-02-02 | Rucci Carolyn M. SVP, Chief Legal Officer | Sold plan | $97.0k69.8k shares |
| 2026-02-02 | Burke Steven Keith SVP, Chief Medical Officer | Sold plan | $94.0k67.7k shares |
| 2026-02-02 | Malabre Richard C SVP, Chief Accounting Officer | Sold plan | $68.8k49.5k shares |
| 2026-02-02 | Ostrowski Erik SVP, CFO, CBO & Treasurer | Sold plan | $48.6k35.0k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2026
| Manager | Shares | Change |
|---|---|---|
| BlackRock, Inc. 0.00% of their portfolio | 18.7m $26.0m | Reduced -625.2k |
| STATE STREET CORP 0.00% of their portfolio | 11.6m $16.1m | Reduced -2.1m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 11.2m $15.5m | First filing |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 6.5m $9.0m | Added +175.1k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 3.6m $5.0m | Reduced -1.1m |
| CITIGROUP INC 0.00% of their portfolio | 2.9m $4.0m | Added +418.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 2.8m $3.8m | Added +506.0k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 2.4m $3.3m | Reduced -595.6k |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 2.4m $3.3m | Added +731.2k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 2.2m $3.1m | First filing |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 2.0m $2.8m | Reduced -165.2k |
| Nantahala Capital Management, LLC 0.17% of their portfolio | 2.0m $2.8m | Unchanged |
| NORTHERN TRUST CORP 0.00% of their portfolio | 1.9m $2.7m | Reduced -367.6k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 1.8m $2.5m | Reduced -1.8m |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 1.8m $2.5m | Added +1.1m |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 1.8m $2.5m | First filing |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 1.5m $2.0m | Added +765.1k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 1.4m $1.9m | Reduced -3.3m |
| ACADIAN ASSET MANAGEMENT LLC 0.00% of their portfolio | 1.4m $1.9m | Reduced -822.7k |
| FMR LLC 0.00% of their portfolio | 1.3m $1.9m | Added +209.7k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 1.3m $1.8m | Added +1.2m |
| HRT FINANCIAL LP 0.00% of their portfolio | 976.9k $1.4m | Reduced -642.4k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 921.9k $1.3m | Reduced -649.1k |
| UBS Group AG 0.00% of their portfolio | 769.5k $1.1m | Reduced -102.1k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 722.1k $1.0m | Added +74.4k |
| Invesco Ltd. 0.00% of their portfolio | 720.1k $1.0m | Added +50.9k |
| WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio | 707.7k $983.8k | Reduced -78.7k |
| Voleon Capital Management LP 0.02% of their portfolio | 675.7k $939.2k | Added +404.4k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 665.6k $925.2k | Reduced -64.8k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 650.9k $904.7k | Reduced -16.1k |
| Hennion & Walsh Asset Management, Inc. 0.03% of their portfolio | 633.3k $880.2k | Added +134.3k |
| LOS ANGELES CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 601.3k $835.8k | Added +571.7k |
| Nuveen, LLC 0.00% of their portfolio | 596.6k $829.3k | Added +3.6k |
| MORGAN STANLEY 0.00% of their portfolio | 581.3k $808.0k | Reduced -647.5k |
| JACOBS LEVY EQUITY MANAGEMENT, INC 0.00% of their portfolio | 429.7k $597.2k | Reduced -228.1k |
| Squarepoint Ops LLC 0.00% of their portfolio | 422.8k $587.7k | Reduced -800.2k |
| AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio | 416.0k $578.2k | Unchanged |
| MANGROVE PARTNERS IM, LLC 0.04% of their portfolio | 376.0k $522.6k | New |
| Rafferty Asset Management, LLC 0.00% of their portfolio | 327.1k $454.7k | Reduced -171.5k |
| VIRTUS ADVISERS, LLC 0.20% of their portfolio | 308.0k $428.1k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 306.9k $426.6k | Reduced -10.5k |
| CANADA PENSION PLAN INVESTMENT BOARD 0.00% of their portfolio | 287.5k $399.6k | Reduced -35.4k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 274.4k $381.5k | Reduced -479.5k |
| Man Group plc 0.00% of their portfolio | 257.9k $358.4k | Added +49.3k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 249.2k $347.0k | Added +36.5k |
| Graham Capital Management, L.P. 0.01% of their portfolio | 248.4k $345.2k | Reduced -128.2k |
| XTX Topco Ltd 0.01% of their portfolio | 244.5k $339.8k | Reduced -228.0k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 238.9k $384.7k | Unchanged |
| PANAGORA ASSET MANAGEMENT INC 0.00% of their portfolio | 236.1k $328.2k | Unchanged |
| ALPS ADVISORS INC 0.00% of their portfolio | 218.1k $303.1k | Added +179 |
| EntryPoint Capital, LLC 0.08% of their portfolio | 201.7k $280.4k | Added +74.2k |
| SAPIENT CAPITAL LLC 0.00% of their portfolio | 200.0k $278.0k | Unchanged |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 196.6k $273.2k | Added +2.8k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 189.5k $263.4k | Added +24.8k |
| Wealthspire Advisors, LLC 0.00% of their portfolio | 180.0k $250.2k | Unchanged |
| Creative Planning 0.00% of their portfolio | 176.6k $245.4k | Added +29.8k |
| Round Rock Advisors LLC 0.04% of their portfolio | 166.1k $230.9k | Unchanged |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 148.1k $205.8k | New |
| PROFUND ADVISORS LLC 0.01% of their portfolio | 147.1k $204.5k | Reduced -37.6k |
| State of Alaska, Department of Revenue 0.00% of their portfolio | 146.1k $202.0k | Unchanged |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 143.2k $197.5k | Reduced -3.5k |
| BARCLAYS PLC 0.00% of their portfolio | 142.2k $197.6k | Reduced -781.3k |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 129.2k $179.5k | Reduced -121.4k |
| Elevation Advisory Partners LLC 0.17% of their portfolio | 120.0k $181.2k | First filing |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 114.0k $150.5k | Reduced -80.0k |
| Caitong International Asset Management Co., Ltd 0.03% of their portfolio | 103.7k $144.1k | Added +83.0k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 102.1k $142.0k | First filing |
| Fiduciary Trust Co 0.00% of their portfolio | 100.0k $139.0k | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 98.5k $136.9k | Reduced -187.3k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 97.7k $135.8k | Reduced -35.4k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 92.3k $128.3k | Reduced -33.2k |
| Quadrature Capital Ltd 0.00% of their portfolio | 89.3k $124.1k | Added +72.7k |
| LPL Financial LLC 0.00% of their portfolio | 85.5k $118.9k | Added +24.3k |
| WINTON GROUP Ltd 0.00% of their portfolio | 84.5k $117.4k | Added +19.3k |
| Engineers Gate Manager LP 0.00% of their portfolio | 79.6k $110.6k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 79.1k $109.9k | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 74.7k $103.8k | Added +9.5k |
| SG Americas Securities, LLC 0.00% of their portfolio | 73.1k $102.0k | Reduced -100.4k |
| RAYMOND JAMES FINANCIAL INC 0.00% of their portfolio | 72.9k $101.3k | Reduced -7.7k |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 69.1k $96.0k | Unchanged |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 69.0k $95.9k | Reduced -51.4k |
| INTECH INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 66.1k $91.8k | Reduced -37.3k |
| CWA Asset Management Group, LLC 0.00% of their portfolio | 59.0k $82.0k | Unchanged |
| Orchard Capital Management, LLC 0.10% of their portfolio | 53.5k $74.4k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 52.7k $73.3k | Added +27.8k |
| PDS Planning, Inc 0.00% of their portfolio | 50.0k $69.5k | Unchanged |
| SEI INVESTMENTS CO 0.00% of their portfolio | 49.9k $69.4k | Unchanged |
| Headlands Technologies LLC 0.01% of their portfolio | 48.7k $67.6k | New |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 44.4k $61.7k | Reduced -1.8k |
| Y-Intercept (Hong Kong) Ltd 0.00% of their portfolio | 42.4k $59.0k | New |
| E Fund Management Co., Ltd. 0.00% of their portfolio | 41.1k $57.2k | First filing |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 40.3k $56.0k | Reduced -11.2k |
| Arax Advisory Partners 0.00% of their portfolio | 39.1k $54.4k | Added +9 |
| PFG Private Wealth Management, LLC 0.02% of their portfolio | 37.3k $51.9k | New |
| FRANKLIN RESOURCES INC 0.00% of their portfolio | 37.3k $51.8k | Reduced -144.3k |
| ProShare Advisors LLC 0.00% of their portfolio | 36.7k $51.0k | Reduced -9.6k |
| Empirical Asset Management, LLC 0.01% of their portfolio | 35.0k $48.6k | Unchanged |
| HighTower Advisors, LLC 0.00% of their portfolio | 31.1k $43.3k | Added +3.9k |
| Focus Partners Wealth 0.00% of their portfolio | 29.8k $41.5k | Reduced -16.9k |
| ROYCE & ASSOCIATES LP 0.00% of their portfolio | 28.4k $39.4k | New |