Vault-13

AGIOS PHARMACEUTICALS INC AGIO

COM · Common Stock · CUSIP 00847X104 · ISIN US00847X1046

A public American pharmaceutical company

217 institutional holders -5 vs Q1 2025
61,699,11761.7m shares reported held*
106.2% of all shares outstanding*
$2.1bnreported value*
21 new 87 added 77 reduced 24 sold out net bought ≈ $54.6m (+1.7m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($504.7k this quarter). Holder counts are more reliable. Shares outstanding: 58.1m as of 2025-07-25, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $33.26. Options: 9 managers hold calls ($11.2m notional), 7 hold puts ($8.7m).

Trends to Q2 2025

Institutional holders

Managers reporting a position, each quarter

0100200300Q3 22: 169Q4 22: 161Q1 23: 166Q2 23: 154Q3 23: 147Q4 23: 171Q1 24: 188Q2 24: 207Q3 24: 209Q4 24: 226Q1 25: 222Q2 25: 217217Q3 22Q2 23Q1 24Q4 24Q2 25
Numbers
QuarterHolders
Q3 2022169
Q4 2022161
Q1 2023166
Q2 2023154
Q3 2023147
Q4 2023171
Q1 2024188
Q2 2024207
Q3 2024209
Q4 2024226
Q1 2025222
Q2 2025217

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
2000200Q3 23: 66 bought or addedQ3 23: 62 cut or sold outQ4 23: 90 bought or addedQ4 23: 57 cut or sold outQ4 23Q1 24: 101 bought or addedQ1 24: 81 cut or sold outQ2 24: 98 bought or addedQ2 24: 108 cut or sold outQ2 24Q3 24: 101 bought or addedQ3 24: 93 cut or sold outQ4 24: 116 bought or addedQ4 24: 95 cut or sold outQ4 24Q1 25: 107 bought or addedQ1 25: 116 cut or sold outQ2 25: 108 bought or addedQ2 25: 101 cut or sold outQ2 25
Numbers
QuarterBought or addedCut or sold out
Q3 20236662
Q4 20239057
Q1 202410181
Q2 202498108
Q3 202410193
Q4 202411695
Q1 2025107116
Q2 2025108101

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$10m$20m$30mQ3 24 calls: $17.8mQ3 24 puts: $21.1mQ3 24P/C 1.18Q4 24 calls: $9.0mQ4 24 puts: $11.5mQ4 24P/C 1.28Q1 25 calls: $10.6mQ1 25 puts: $11.1mQ1 25P/C 1.05Q2 25 calls: $11.2mQ2 25 puts: $8.7mQ2 25P/C 0.77
Numbers
QuarterCallsPutsP/C
Q3 2024$17.8m$21.1m1.18
Q4 2024$9.0m$11.5m1.28
Q1 2025$10.6m$11.1m1.05
Q2 2025$11.2m$8.7m0.77

Biggest buyers

Paradigm Biocapital Advisors LP New +1,142,511+1.1m
TCG Crossover Management, LLC New +697,003+697.0k
Rock Springs Capital Management LP Added +647,565+647.6k
WELLINGTON MANAGEMENT GROUP LLP Added +397,667+397.7k
Caligan Partners LP Added +369,978+370.0k
MILLENNIUM MANAGEMENT LLC Added +247,130+247.1k
ORBIMED ADVISORS LLC Added +232,400+232.4k
CITADEL ADVISORS LLC Added +217,971+218.0k
Woodline Partners LP Added +212,687+212.7k
Frazier Life Sciences Management, L.P. Added +209,900+209.9k

Biggest sellers

Polar Capital Holdings Plc Sold out -1,002,036-1.0m
ARMISTICE CAPITAL, LLC Reduced -880,000-880.0k
STATE STREET CORP Reduced -498,366-498.4k
BlackRock, Inc. Reduced -274,986-275.0k
Cutter Capital Management, LP Sold out -235,350-235.3k
ArrowMark Colorado Holdings LLC Reduced -168,932-168.9k
DIMENSIONAL FUND ADVISORS LP Reduced -155,980-156.0k
Walleye Capital LLC Sold out -150,511-150.5k
Casdin Capital, LLC Reduced -150,000-150.0k
VOLORIDGE INVESTMENT MANAGEMENT, LLC Reduced -144,248-144.2k

Biggest calls

DIADEMA PARTNERS LP Added $4.1m122.1k shares
Caption Management, LLC Added $2.4m73.0k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $2.0m60.0k shares
CITADEL ADVISORS LLC Added $1.1m33.3k shares
GROUP ONE TRADING LLC Added $658.5k19.8k shares
SIMPLEX TRADING, LLC Reduced $631.0k19.0k shares
WOLVERINE TRADING, LLC New $274.5k8.2k shares
Persistent Asset Partners Ltd Added $63.5k316 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

Caption Management, LLC Added $5.4m162.4k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $1.2m37.2k shares
CITADEL ADVISORS LLC Reduced $1.0m30.8k shares
JPMORGAN CHASE & CO New $612.0k18.4k shares
GROUP ONE TRADING LLC Reduced $372.5k11.2k shares
SIMPLEX TRADING, LLC New $6.0k200 shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
FARALLON CAPITAL MANAGEMENT, L.L.C. 13G · institution filed 2026-08-03 9.9% 5.9m≈ $219.6m 2026-08-03
Farallon Capital Partners, L.P. 13G · passive investor -1.1 pts · filed 2026-02-09 8.8% -1.1 pts 5.2m≈ $191.5m 2026-02-09
BlackRock, Inc. 13G · institution filed 2025-07-17 7.8% 4.5m≈ $167.5m 2025-07-17
STATE STREET CORP 13G · institution new · filed 2026-02-09 5.3% new 3.1m≈ $115.3m 2026-02-09
VANGUARD CAPITAL MANAGEMENT LLC 13G · institution new · filed 2026-04-29 5.3% new 3.1m≈ $114.6m 2026-04-29
D. E. SHAW & CO, L.P. 13G · passive investor new · filed 2026-07-02 5.1% new 3.0m≈ $112.6m 2026-07-02
Lynx1 Capital Management LP 13G · passive investor new · filed 2026-05-06 5.1% new 3.0m≈ $111.8m 2026-05-06

Fell to 5% or below in the last year: ARMISTICE CAPITAL, LLC (4.6%, 2026-05-15), VANGUARD GROUP INC (0.0%, 2026-03-26; now reported by VANGUARD CAPITAL MANAGEMENT LLC), Bellevue Group AG (0.0%, 2025-12-05), Paradigm Biocapital Advisors LP (4.9%, 2025-11-14)

Insider purchases and sales in Q2 2025

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
10010Q3 23: 0 buyingQ3 23: 5 sellingQ4 23: 0 buyingQ4 23: 0 sellingQ4 23Q1 24: 0 buyingQ1 24: 9 sellingQ2 24: 0 buyingQ2 24: 3 sellingQ2 24Q3 24: 0 buyingQ3 24: 3 sellingQ4 24: 0 buyingQ4 24: 4 sellingQ4 24Q1 25: 0 buyingQ1 25: 6 sellingQ2 25: 0 buyingQ2 25: 6 sellingQ2 25
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20230—5$1.2m$345.7k
Q4 20230—0——
Q1 20240—9$6.4m$1.4m
Q2 20240—3$866.8k$806.3k
Q3 20240—3$761.2k$761.2k
Q4 20240—4$2.3m$2.3m
Q1 20250—6$850.8k$850.8k
Q2 20250—6$1.2m$1.2m
DateInsiderTradeSharesPrice ValueTheir holding
2025-06-24 Goff Brian Chief Executive Officer, director Sold plan 18,700 $33.54 $627.2k18.7k shares -14%
2025-06-24 Gheuens Sarah Chief Medical Officer Sold plan 2,909 $33.54 $97.6k2.9k shares -5%
2025-06-24 Burns James William Chief Legal Officer Sold plan 2,799 $33.54 $93.9k2.8k shares -9%
2025-06-24 Milanova Tsveta Chief Commercial Officer Sold plan 2,770 $33.54 $92.9k2.8k shares -10%
2025-06-24 Jones Cecilia Chief Financial Officer Sold plan 1,780 $33.54 $59.7k1.8k shares -6%
2025-04-10 FOUSE JACQUALYN A Director Sold plan 7,497 $25.90 $194.2k7.5k shares -5%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2025

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FARALLON CAPITAL MANAGEMENT, L.L.C. 0.87% of their portfolio SAN FRANCISCO, CA 5,767,4665.8m $191.8m $191.8m 0.87% Added +67.0k +67,000
2 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 5,682,0195.7m $189.0m $189.0m 0.00% Added +77.4k +77,428
3 BlackRock, Inc. 0.00% of their portfolio New York, NY 4,833,7604.8m $160.8m $160.8m 0.00% Reduced -275.0k -274,986
4 Bellevue Group AG 2.63% of their portfolio ZURICH, V8 3,590,1503.6m $119.4m $119.4m 2.63% Added +75.0k +75,000
5 Erste Asset Management GmbH 0.65% of their portfolio VIENNA, C4 2,326,4892.3m $77.4m $77.4m 0.65% Added +96.6k +96,589
6 Commodore Capital LP 5.46% of their portfolio NEW YORK, NY 2,325,0002.3m $77.3m $77.3m 5.46% Added +140.0k +140,000
7 PRICE T ROWE ASSOCIATES INC /MD/ 0.01% of their portfolio BALTIMORE, MD 2,274,2492.3m $75.6m $75.6m 0.01% Reduced -27.1k -27,104
8 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 1,951,1132.0m $64.9m $64.9m 0.00% Reduced -498.4k -498,366
9 MACQUARIE GROUP LTD 0.08% of their portfolio Sydney, NSW 2000, C3 1,900,5961.9m $63.2m $63.2m 0.08% Added +50.1k +50,052
10 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 1,405,7551.4m $46.8m $46.8m 0.00% Added +11.2k +11,174
11 Frazier Life Sciences Management, L.P. 1.70% of their portfolio PALO ALTO, CA 1,279,7541.3m $42.6m $42.6m 1.70% Added +209.9k +209,900
12 ARMISTICE CAPITAL, LLC 1.47% of their portfolio NEW YORK, NY 1,168,0001.2m $38.8m $38.8m 1.47% Reduced -880.0k -880,000
13 Paradigm Biocapital Advisors LP 1.62% of their portfolio NEW YORK, NY 1,142,5111.1m $38.0m $38.0m 1.62% New
14 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 1,120,3081.1m $37.3m $37.3m 0.00% Reduced -15.3k -15,284
15 DIMENSIONAL FUND ADVISORS LP 0.01% of their portfolio AUSTIN, TX 1,106,0931.1m $36.8m $36.8m 0.01% Reduced -156.0k -155,980
16 CITADEL ADVISORS LLC 0.03% of their portfolio MIAMI, FL 1,081,4701.1m $36.0m $36.0m 0.03% Added +218.0k +217,971
17 Caligan Partners LP 6.92% of their portfolio NEW YORK, NY 1,071,2581.1m $35.6m $35.6m 6.92% Added +370.0k +369,978
18 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 1,027,4171.0m $34.2m $34.2m 0.00% Reduced -21.9k -21,943
19 BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.08% of their portfolio Paris, I0 1,016,8911.0m $33.8m $33.8m 0.08% Reduced -8.8k -8,828
20 Rock Springs Capital Management LP 2.05% of their portfolio Baltimore, MD 989,745989.7k $32.9m $32.9m 2.05% Added +647.6k +647,565
21 DEUTSCHE BANK AG\ 0.01% of their portfolio FRANKFURT AM MAIN, 2M 921,586921.6k $30.7m $30.7m 0.01% Reduced -7.4k -7,384
22 Fisher Asset Management, LLC 0.01% of their portfolio PLANO, TX 877,540877.5k $29.2m $29.2m 0.01% Reduced -81.8k -81,799
23 GW&K Investment Management, LLC 0.26% of their portfolio BOSTON, MA 868,618868.6k $28.9m $28.9m 0.26% Added +51.1k +51,092
24 ADAGE CAPITAL PARTNERS GP, L.L.C. 0.04% of their portfolio Boston, MA 791,000791.0k $26.3m $26.3m 0.04% Added +48.0k +48,000
25 TCG Crossover Management, LLC 2.65% of their portfolio PALO ALTO, CA 697,003697.0k $23.2m $23.2m 2.65% New
26 MARSHALL WACE, LLP 0.03% of their portfolio LONDON, X0 684,669684.7k $22.8m $22.8m 0.03% Added +163.8k +163,796
27 ArrowMark Colorado Holdings LLC 0.39% of their portfolio Denver, CO 658,691658.7k $21.9m $21.9m 0.39% Reduced -168.9k -168,932
28 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 648,061648.1k $21.6m $21.6m 0.00% Reduced -10.6k -10,591
29 SCS Capital Management LLC 0.22% of their portfolio BOSTON, MA 604,085604.1k $20.1m $20.1m 0.22% Reduced -7.0k -7,013
30 D. E. Shaw & Co., Inc. 0.02% of their portfolio New York, NY 596,202596.2k $19.8m $19.8m 0.02% Added +41.4k +41,382
31 ORBIMED ADVISORS LLC 0.47% of their portfolio New York, NY 557,900557.9k $18.6m $18.6m 0.47% Added +232.4k +232,400
32 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 556,805556.8k $18.5m $18.5m 0.00% Reduced -19.5k -19,453
33 Connor, Clark & Lunn Investment Management Ltd. 0.06% of their portfolio VANCOUVER, A1 505,225505.2k $16.8m $16.8m 0.06% Added +118.7k +118,702
34 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 476,041476.0k $15.8m $15.8m 0.00% Added +11.1k +11,083
35 BOOTHBAY FUND MANAGEMENT, LLC 0.46% of their portfolio NEW YORK, NY 447,019447.0k $14.9m $14.9m 0.46% Added +185.8k +185,798
36 WELLINGTON MANAGEMENT GROUP LLP 0.00% of their portfolio Boston, MA 422,129422.1k $14.0m $14.0m 0.00% Added +397.7k +397,667
37 Artisan Partners Limited Partnership 0.02% of their portfolio Milwaukee, WI 389,984390.0k $13.0m $13.0m 0.02% Reduced -20.7k -20,688
38 Eagle Health Investments LP 2.72% of their portfolio Greenwich, CT 330,830330.8k $11.0m $11.0m 2.72% Unchanged
39 MILLENNIUM MANAGEMENT LLC 0.01% of their portfolio NEW YORK, NY 300,203300.2k $10.0m $10.0m 0.01% Added +247.1k +247,130
40 Pictet Asset Management Holding SA 0.01% of their portfolio CAROUGE, V8 294,740294.7k $9.9m $9.9m 0.01% Reduced -16.0k -16,041
41 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 291,965292.0k $9.7m $9.7m 0.00% Reduced -2.7k -2,658
42 Palo Alto Investors LP 1.90% of their portfolio PALO ALTO, CA 268,783268.8k $8.9m $8.9m 1.90% Reduced -7.8k -7,795
43 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 266,654266.7k $8.9m $8.9m 0.00% Added +3.2k +3,204
44 CenterBook Partners LP 0.45% of their portfolio GREENWICH, CT 243,063243.1k $8.1m $8.1m 0.45% Added +134.6k +134,554
45 Woodline Partners LP 0.04% of their portfolio San Francisco, CA 233,068233.1k $7.8m $7.8m 0.04% Added +212.7k +212,687
46 AXA S.A. 0.02% of their portfolio PARIS, I0 225,367225.4k $7.5m $7.5m 0.02% Added +248 +248
47 NORDEA INVESTMENT MANAGEMENT AB 0.01% of their portfolio STOCKHOLM, V7 224,746224.7k $7.5m $7.5m 0.01% Added +573 +573
48 UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% of their portfolio NEW YORK, NY 217,402217.4k $7.2m $7.2m 0.00% Added +70.1k +70,126
49 BAKER BROS. ADVISORS LP 0.06% of their portfolio NEW YORK, NY 189,866189.9k $6.3m $6.3m 0.06% New
50 VOLORIDGE INVESTMENT MANAGEMENT, LLC 0.02% of their portfolio JUPITER, FL 187,395187.4k $6.2m $6.2m 0.02% Reduced -144.2k -144,248
51 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 180,704180.7k $6.0m $6.0m 0.00% Added +67.6k +67,551
52 TD Asset Management Inc 0.00% of their portfolio Toronto, A6 168,194168.2k $5.6m $5.6m 0.00% Reduced -9.9k -9,878
53 PRUDENTIAL FINANCIAL INC 0.01% of their portfolio NEWARK, NJ 158,359158.4k $5.3m $5.3m 0.01% Reduced -45.9k -45,883
54 Patient Square Capital LP 1.68% of their portfolio MENLO PARK, CA 139,732139.7k $4.6m $4.6m 1.68% Unchanged
55 Allianz Asset Management GmbH 0.01% of their portfolio MUNICH, 2M 138,898138.9k $4.6m $4.6m 0.01% Added +46.7k +46,665
56 CANTOR FITZGERALD, L. P. 0.11% of their portfolio NEW YORK, NY 134,200134.2k $4.5m $4.5m 0.11% Added +102.2k +102,200
57 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 132,083132.1k $4.4m $4.4m 0.00% Added +512 +512
58 Hudson Bay Capital Management LP 0.03% of their portfolio STAMFORD, CT 130,000130.0k $4.3m $4.3m 0.03% Added +19.3k +19,280
59 AMERICAN CENTURY COMPANIES INC 0.00% of their portfolio KANSAS CITY, MO 127,647127.6k $4.2m $4.2m 0.00% Added +12.7k +12,700
60 Nuveen, LLC 0.00% of their portfolio CHARLOTTE, NC 119,580119.6k $4.0m $4.0m 0.00% Added +36.2k +36,171
61 UBS Group AG 0.00% of their portfolio ZURICH, V8 118,834118.8k $4.0m $4.0m 0.00% Reduced -12.8k -12,808
62 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 112,617112.6k $3.7m $3.7m 0.00% Added +5.2k +5,250
63 Swiss National Bank 0.00% of their portfolio ZURICH, V8 109,460109.5k $3.6m $3.6m 0.00% Added +10.0k +10,000
64 Casdin Capital, LLC 0.30% of their portfolio New York, NY 100,000100.0k $3.3m $3.3m 0.30% Reduced -150.0k -150,000
65 Trexquant Investment LP 0.04% of their portfolio STAMFORD, CT 98,40198.4k $3.3m $3.3m 0.04% New
66 AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio Greenwich, CT 96,89696.9k $3.2m $3.2m 0.00% Added +45.4k +45,407
67 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 89,88189.9k $3.0m $3.0m 0.00% Added +3.0k +3,039
68 ALGERT GLOBAL LLC 0.06% of their portfolio SAN FRANCISCO, CA 88,83088.8k $3.0m $3.0m 0.06% Added +14.0k +14,020
69 SILVERCREST ASSET MANAGEMENT GROUP LLC 0.02% of their portfolio NEW YORK, NY 82,67982.7k $2.7m $2.7m 0.02% Unchanged
70 MOORE CAPITAL MANAGEMENT, LP 0.05% of their portfolio NEW YORK, NY 80,00080.0k $2.7m $2.7m 0.05% Added +20.0k +20,000
71 HighVista Strategies LLC 0.86% of their portfolio BOSTON, MA 70,12770.1k $2.3m $2.3m 0.86% Added +26.0k +26,022
72 CAPITAL FUND MANAGEMENT S.A. 0.03% of their portfolio PARIS, I0 68,50268.5k $2.3m $2.3m 0.03% Reduced -3.8k -3,800
73 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 68,10368.1k $2.3m $2.3m 0.00% Reduced -13.9k -13,859
74 Qube Research & Technologies Ltd 0.00% of their portfolio LONDON, X0 67,37967.4k $2.2m $2.2m 0.00% Reduced -60.6k -60,601
75 Legal & General Group Plc 0.00% of their portfolio London, X0 64,30564.3k $2.1m $2.1m 0.00% Added +4.3k +4,262
76 ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio NASHVILLE, TN 61,47061.5k $2.0m $2.0m 0.00% Reduced -8 -8
77 STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio MADISON, WI 59,10059.1k $2.0m $2.0m 0.00% Reduced -10.6k -10,584
78 OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) 0.05% of their portfolio CHICAGO, IL 56,81056.8k $1.9m $1.9m 0.05% Reduced -1.9k -1,912
79 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 56,48956.5k $1.9m $1.9m 0.00% Reduced -119.6k -119,639
80 Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% of their portfolio FRANKFURT AM MAIN, 2M 55,28455.3k $1.8m $1.8m 0.00% Added +633 +633
81 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 52,25252.3k $1.7m $1.7m 0.00% Added +5.4k +5,441
82 FRANKLIN RESOURCES INC 0.00% of their portfolio San Mateo, CA 50,10850.1k $1.7m $1.7m 0.00% Reduced -18.0k -17,964
83 VIRGINIA RETIREMENT SYSTEMS ET Al 0.01% of their portfolio RICHMOND, VA 49,66149.7k $1.7m $1.7m 0.01% Added +10.4k +10,400
84 Rafferty Asset Management, LLC 0.01% of their portfolio New York, NY 49,40349.4k $1.6m $1.6m 0.01% Reduced -44.2k -44,224
85 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 47,65947.7k $1.6m $1.6m 0.00% Added +671 +671
86 PANAGORA ASSET MANAGEMENT INC 0.01% of their portfolio BOSTON, MA 47,19047.2k $1.6m $1.6m 0.01% Reduced -31 -31
87 Schonfeld Strategic Advisors LLC 0.01% of their portfolio NEW YORK, NY 46,34646.3k $1.5m $1.5m 0.01% Added +22.7k +22,746
88 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 46,32846.3k $1.5m $1.5m 0.00% Added +13.1k +13,091
89 Granahan Investment Management, LLC 0.06% of their portfolio WALTHAM, MA 41,88641.9k $1.4m $1.4m 0.06% Reduced -90.2k -90,222
90 DekaBank Deutsche Girozentrale 0.00% of their portfolio FRANKFURT, 2M 40,00040.0k $1.3m $1.3m 0.00% Unchanged
91 MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio CAUSEWAY BAY, K3 39,57939.6k $1.3m $1.3m 0.00% Reduced -3.7k -3,748
92 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 39,09339.1k $1.3m $1.3m 0.00% Unchanged
93 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 37,69437.7k $1.3m $1.3m 0.00% Reduced -30.4k -30,443
94 OAK RIDGE INVESTMENTS LLC 0.09% of their portfolio Chicago, IL 37,25237.3k $1.2m $1.2m 0.09% Reduced -1.8k -1,835
95 HARBOR CAPITAL ADVISORS, INC. 0.05% of their portfolio CHICAGO, IL 37,02437.0k $1.2m $1.2m 0.05% Added +1.3k +1,295
96 KENNEDY CAPITAL MANAGEMENT LLC 0.03% of their portfolio ST LOUIS, MO 36,70536.7k $1.2m $1.2m 0.03% Reduced -26.2k -26,248
97 FIRST TRUST ADVISORS LP 0.00% of their portfolio Wheaton, IL 36,42736.4k $1.2m $1.2m 0.00% Reduced -903 -903
98 ADAR1 Capital Management, LLC 0.19% of their portfolio AUSTIN, TX 35,90035.9k $1.2m $1.2m 0.19% Added +8.0k +8,000
99 EDGEWOOD MANAGEMENT LLC 0.00% of their portfolio GREENWICH, CT 35,00035.0k $1.2m $1.2m 0.00% Unchanged
100 MetLife Investment Management, LLC 0.01% of their portfolio Whippany, NJ 34,03234.0k $1.1m $1.1m 0.01% Unchanged