INVIVYD INC IVVD
COM · Common Stock · CUSIP 00534A102 · ISIN US00534A1025
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersNew Haven, CT
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($11.5k this quarter). Holder counts are more reliable. Shares outstanding: 294.8m as of 2026-07-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $0.87. Options: 5 managers hold calls ($634.4k notional), 5 hold puts ($355.9k).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 78 |
| Q4 2022 | 82 |
| Q1 2023 | 71 |
| Q2 2023 | 58 |
| Q3 2023 | 59 |
| Q4 2023 | 60 |
| Q1 2024 | 87 |
| Q2 2024 | 81 |
| Q3 2024 | 77 |
| Q4 2024 | 78 |
| Q1 2025 | 80 |
| Q2 2025 | 69 |
| Q3 2025 | 78 |
| Q4 2025 | 116 |
| Q1 2026 | 140 |
| Q2 2026 | 125 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q3 2024 | 31 | 39 |
| Q4 2024 | 34 | 32 |
| Q1 2025 | 37 | 39 |
| Q2 2025 | 29 | 54 |
| Q3 2025 | 47 | 33 |
| Q4 2025 | 74 | 26 |
| Q1 2026 | 78 | 41 |
| Q2 2026 | 71 | 71 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $345.4k | $268.6k | 0.78 |
| Q4 2025 | $2.9m | $1.2m | 0.42 |
| Q1 2026 | $1.1m | $285.2k | 0.25 |
| Q2 2026 | $634.4k | $355.9k | 0.56 |
Biggest buyers
| BlackRock, Inc. | Added | +11.9m |
| BVF INC/IL | Added | +8.6m |
| Point72 Asset Management, L.P. | Added | +7.5m |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +2.9m |
| MORGAN STANLEY | Added | +2.3m |
| CITADEL ADVISORS LLC | Added | +2.0m |
| VANGUARD PORTFOLIO MANAGEMENT LLC | New | +1.4m |
| NORTHERN TRUST CORP | Added | +1.2m |
| Siren, L.L.C. | Added | +1.0m |
| CANTOR FITZGERALD, L. P. | New | +900.2k |
Biggest sellers
| EVENTIDE ASSET MANAGEMENT, LLC | Sold out | -9.1m |
| STEMPOINT CAPITAL LP | Sold out | -3.7m |
| Driehaus Capital Management LLC | Reduced | -3.6m |
| Balyasny Asset Management L.P. | Sold out | -3.5m |
| STATE STREET CORP | Reduced | -3.5m |
| Saturn V Capital Management LP | Reduced | -2.6m |
| PERCEPTIVE ADVISORS LLC | Reduced | -2.4m |
| MILLENNIUM MANAGEMENT LLC | Reduced | -2.3m |
| GOLDMAN SACHS GROUP INC | Reduced | -1.6m |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -1.4m |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $241.6k277.7k shares |
| CITADEL ADVISORS LLC | Added | $138.4k158.6k shares |
| JANE STREET GROUP, LLC | Reduced | $117.0k134.1k shares |
| SIMPLEX TRADING, LLC | Reduced | $107.0k122.7k shares |
| GROUP ONE TRADING LLC | Reduced | $30.4k34.9k shares |
Biggest puts
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $281.1k323.1k shares |
| JANE STREET GROUP, LLC | Added | $37.2k42.6k shares |
| CITADEL ADVISORS LLC | Added | $23.6k27.0k shares |
| SIMPLEX TRADING, LLC | Added | $9.6k11.0k shares |
| GROUP ONE TRADING LLC | Reduced | $4.4k5.1k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| JANUS HENDERSON GROUP PLC 13G · institution +0.5 pts · filed 2025-11-14 | 12.1% |
| BIOTECHNOLOGY VALUE FUND L P 13G · passive investor +1.0 pts · filed 2026-08-14 | 10.0% |
| Adimab, LLC 13D · may seek influence -1.5 pts · filed 2025-12-29 | 7.3% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor -2.9 pts · filed 2026-05-15 | 7.0% |
| MAVERICK CAPITAL LTD 13G · passive investor -1.8 pts · filed 2026-02-13 | 6.7% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor -1.6 pts · filed 2026-08-14 | 6.3% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-28 | 5.5% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), Soleus Private Equity Fund III, L.P. (2.8%, 2026-02-12), Deep Track Capital, LP (0.0%, 2025-11-14), MITHRIL II LP (4.8%, 2025-11-12)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 1 | $836.0k | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 5 | $107.4k | $107.4k |
| Q4 2025 | 1 | $125.0k | 0 | — | — |
| Q1 2026 | 0 | — | 5 | $227.7k | $227.7k |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 0 | — | 5 | $113.4k | $113.4k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-08-18 | Andersen Jill Chief Legal Officer, Secretary | Sold plan | $25.8k30.7k shares |
| 2026-08-18 | Duke William E. Chief Financial Officer | Sold plan | $15.5k18.4k shares |
| 2026-08-18 | Green Julie Chief Human Resources Officer | Sold plan | $15.5k18.4k shares |
| 2026-08-18 | Lee Timothy Edward Chief Commercial Officer | Sold plan | $15.5k18.4k shares |
| 2026-08-18 | Allen Robert D. III Chief Scientific Officer | Sold plan | $14.3k17.0k shares |
| 2026-08-17 | Andersen Jill Chief Legal Officer, Secretary | Sold plan | $26.8k37.3k shares |
| 2026-08-17 | Lee Timothy Edward Chief Commercial Officer | Sold plan | $16.1k22.4k shares |
| 2026-08-17 | Duke William E. Chief Financial Officer | Sold plan | $16.1k22.4k shares |
| 2026-08-17 | Green Julie Chief Human Resources Officer | Sold plan | $16.1k22.4k shares |
| 2026-08-17 | Allen Robert D. III Chief Scientific Officer | Sold plan | $14.9k20.7k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Jupiter Topco LLC 0.01% of their portfolio | 34.2m $30.0m | First filing |
| BVF INC/IL 0.63% of their portfolio | 28.2m $24.6m | Added +8.6m |
| MAVERICK CAPITAL LTD 0.15% of their portfolio | 19.0m $16.6m | Unchanged |
| PERCEPTIVE ADVISORS LLC 0.25% of their portfolio | 18.5m $16.1m | Reduced -2.4m |
| BlackRock, Inc. 0.00% of their portfolio | 16.1m $14.1m | Added +11.9m |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 10.5m $9.2m | Added +422.2k |
| M28 Capital Management LP 17.11% of their portfolio | 9.2m $8.1m | Unchanged |
| Saturn V Capital Management LP 1.05% of their portfolio | 8.4m $7.3m | Reduced -2.6m |
| Soleus Capital Management, L.P. 0.23% of their portfolio | 7.7m $6.7m | Unchanged |
| Point72 Asset Management, L.P. 0.01% of their portfolio | 7.5m $6.6m | Added +7.5m |
| MORGAN STANLEY 0.00% of their portfolio | 5.7m $5.0m | Added +2.3m |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 5.4m $4.7m | Added +2.9m |
| Siren, L.L.C. 0.09% of their portfolio | 5.0m $4.4m | Added +1.0m |
| Driehaus Capital Management LLC 0.02% of their portfolio | 4.8m $4.2m | Reduced -3.6m |
| ADAR1 Capital Management, LLC 0.16% of their portfolio | 3.8m $3.3m | Reduced -15.0k |
| ADAGE CAPITAL PARTNERS GP, L.L.C. 0.00% of their portfolio | 3.7m $3.2m | Unchanged |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 3.6m $3.1m | Added +2.0m |
| STATE STREET CORP 0.00% of their portfolio | 3.5m $3.0m | Reduced -3.5m |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 3.3m $2.9m | Added +633.0k |
| Ikarian Capital, LLC 0.38% of their portfolio | 2.7m $2.3m | Unchanged |
| Redmile Group, LLC 0.15% of their portfolio | 2.6m $2.3m | Reduced -50.9k |
| 683 Capital Management, LLC 0.20% of their portfolio | 2.5m $2.2m | Reduced -32.5k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 2.3m $2.0m | Added +363.8k |
| Eversept Partners, LP 0.11% of their portfolio | 2.2m $2.0m | Reduced -39.3k |
| Ensign Peak Advisors, Inc 0.00% of their portfolio | 1.7m $1.5m | Reduced -297.9k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 1.6m $1.4m | Added +1.2m |
| Boxer Capital Management, LLC 0.10% of their portfolio | 1.5m $1.3m | Unchanged |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 1.5m $1.3m | Added +140.3k |
| VANGUARD PORTFOLIO MANAGEMENT LLC 0.00% of their portfolio | 1.4m $1.2m | New |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 1.2m $1.1m | Reduced -2.3m |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 995.3k $868.3k | Added +149.1k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 978.6k $853.7k | Reduced -1.6m |
| CANTOR FITZGERALD, L. P. 0.01% of their portfolio | 900.2k $785.4k | New |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 790.7k $688.0k | Added +205.4k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.01% of their portfolio | 774.6k $675.8k | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.04% of their portfolio | 662.1k $578.0k | Added +334.6k |
| UBS Group AG 0.00% of their portfolio | 552.3k $481.6k | Reduced -62.4k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 517.9k $451.8k | Added +490.7k |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 469.7k $409.8k | Added +351.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 455.5k $397.4k | Reduced -1.4m |
| Invesco Ltd. 0.00% of their portfolio | 454.5k $396.5k | Added +74.1k |
| EMERALD MUTUAL FUND ADVISERS TRUST 0.01% of their portfolio | 428.8k $374.1k | Unchanged |
| Virtus Investment Advisers, LLC 0.09% of their portfolio | 424.9k $370.7k | Added +307.4k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 356.9k $311.2k | Reduced -605.5k |
| Birchview Capital, LP 0.14% of their portfolio | 342.3k $298.6k | New |
| Nuveen, LLC 0.00% of their portfolio | 280.3k $244.6k | New |
| Squarepoint Ops LLC 0.00% of their portfolio | 231.5k $201.9k | Reduced -588.5k |
| MML INVESTORS SERVICES, LLC 0.00% of their portfolio | 204.4k $178.3k | Reduced -17.5k |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 176.5k $154.0k | Added +176.3k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 172.7k $151.0k | New |
| Verdad Advisers, LP 0.14% of their portfolio | 172.4k $150.4k | Added +41.1k |
| FMR LLC 0.00% of their portfolio | 165.6k $144.5k | Added +24.3k |
| COMMONWEALTH EQUITY SERVICES, LLC 0.00% of their portfolio | 162.0k $141.3k | Added +40.4k |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 157.6k $137.4k | New |
| Jain Global LLC 0.00% of their portfolio | 155.3k $135.4k | Added +29.5k |
| MetLife Investment Management, LLC 0.00% of their portfolio | 133.8k $116.7k | New |
| Miller Financial Services LLC 0.09% of their portfolio | 133.0k $116.0k | Added +28.0k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 115.4k $150.0k | New |
| CITIGROUP INC 0.00% of their portfolio | 112.7k $98.3k | Added +2.8k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 109.3k $103.1k | Added +87.7k |
| SIMON QUICK ADVISORS, LLC 0.00% of their portfolio | 106.6k $93.0k | New |
| Knott David M Jr 0.05% of their portfolio | 100.0k $87.2k | Unchanged |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 99.2k $86.5k | Unchanged |
| Voleon Capital Management LP 0.00% of their portfolio | 97.2k $84.8k | New |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% of their portfolio | 96.9k $84.6k | Added +75.6k |
| UNITED CAPITAL FINANCIAL ADVISORS, LLC 0.00% of their portfolio | 96.5k $84.2k | Unchanged |
| EMERALD ADVISERS, LLC 0.00% of their portfolio | 89.9k $78.5k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 82.0k $71.5k | Reduced -44.8k |
| a16z Perennial Management, L.P. 0.01% of their portfolio | 79.9k $69.7k | Unchanged |
| XTX Topco Ltd 0.00% of their portfolio | 72.5k $63.3k | Reduced -72.8k |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 72.5k $63.2k | Added +3.3k |
| Vanguard Global Advisers, LLC 0.00% of their portfolio | 69.3k $60.4k | Unchanged |
| Police & Firemen's Retirement System of New Jersey 0.00% of their portfolio | 62.1k $54.2k | New |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 60.8k $53.0k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 59.2k $51.7k | New |
| Rangeley Capital, LLC 0.05% of their portfolio | 59.0k $51.5k | Added +14.0k |
| Scientech Research LLC 0.04% of their portfolio | 52.9k $46.1k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 42.1k $36.7k | Added +16.0k |
| VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio | 40.6k $35.4k | New |
| ProShare Advisors LLC 0.00% of their portfolio | 37.2k $32.5k | Added +24.8k |
| PRUDENTIAL FINANCIAL INC 0.00% of their portfolio | 32.9k $28.7k | New |
| Abel Hall, LLC 0.00% of their portfolio | 30.8k $26.8k | New |
| SG Americas Securities, LLC 0.00% of their portfolio | 28.8k $25.0k | New |
| Massar Capital Management, LP 0.01% of their portfolio | 28.3k $24.7k | New |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 27.1k $23.6k | Added +1.4k |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 23.4k $20.4k | Reduced -16.5k |
| OXFORD FINANCIAL GROUP, LTD. LLC 0.00% of their portfolio | 23.1k $20.1k | Unchanged |
| ArchPoint Investors 0.00% of their portfolio | 23.0k $20.1k | New |
| Cetera Investment Advisers 0.00% of their portfolio | 23.0k $20.1k | Added +10.0k |
| Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio | 21.7k $18.9k | Reduced -17.6k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 20.8k $18.0k | Added +18.5k |
| US BANCORP \DE\ 0.00% of their portfolio | 20.5k $17.9k | Unchanged |
| Legal & General Group Plc 0.00% of their portfolio | 20.4k $17.8k | New |
| XPONANCE LLC 0.00% of their portfolio | 20.0k $17.5k | New |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 19.1k $16.7k | New |
| Wealthspire Advisors, LLC 0.00% of their portfolio | 17.6k $15.3k | Unchanged |
| Quantinno Capital Management LP 0.00% of their portfolio | 16.9k $14.7k | New |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 16.8k $14.7k | New |
| STATE OF WISCONSIN INVESTMENT BOARD 0.00% of their portfolio | 16.3k $14.2k | New |
| CIBC Asset Management Inc 0.00% of their portfolio | 15.2k $13.2k | Unchanged |