INVIVYD INC IVVD
COM · Common Stock · CUSIP 00534A102 · ISIN US00534A1025
- SectorHealth care
- IndustryBiological Products, (No Diagnostic Substances)
- HeadquartersNew Haven, CT
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($78.8k this quarter). Holder counts are more reliable. Shares outstanding: 233.1m as of 2025-10-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.10. Options: 5 managers hold calls ($345.4k notional), 4 hold puts ($268.6k).
Trends to Q3 2025
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 78 |
| Q4 2022 | 82 |
| Q1 2023 | 71 |
| Q2 2023 | 58 |
| Q3 2023 | 59 |
| Q4 2023 | 60 |
| Q1 2024 | 87 |
| Q2 2024 | 81 |
| Q3 2024 | 77 |
| Q4 2024 | 78 |
| Q1 2025 | 80 |
| Q2 2025 | 69 |
| Q3 2025 | 78 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2023 | 27 | 26 |
| Q1 2024 | 57 | 23 |
| Q2 2024 | 49 | 47 |
| Q3 2024 | 31 | 39 |
| Q4 2024 | 34 | 32 |
| Q1 2025 | 37 | 39 |
| Q2 2025 | 29 | 54 |
| Q3 2025 | 47 | 33 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q4 2024 | $1.6k | $931 | 0.58 |
| Q1 2025 | $117.6k | $36.2k | 0.31 |
| Q2 2025 | $112.1k | $2.1k | 0.02 |
| Q3 2025 | $345.4k | $268.6k | 0.78 |
Biggest buyers
| JANUS HENDERSON GROUP PLC | New | +25.4m |
| Point72 Asset Management, L.P. | New | +20.3m |
| RA CAPITAL MANAGEMENT, L.P. | New | +17.1m |
| Driehaus Capital Management LLC | New | +10.1m |
| MAVERICK CAPITAL LTD | Added | +8.7m |
| ADAR1 Capital Management, LLC | New | +7.4m |
| 683 Capital Management, LLC | Added | +3.2m |
| Ikarian Capital, LLC | New | +2.1m |
| Eversept Partners, LP | New | +2.0m |
| VANGUARD GROUP INC | Added | +1.8m |
Biggest sellers
| Deep Track Capital, LP | Sold out | -8.6m |
| Bain Capital Life Sciences Investors, LLC | Sold out | -1.8m |
| BlackRock, Inc. | Reduced | -967.7k |
| UBS Group AG | Reduced | -854.0k |
| AQR CAPITAL MANAGEMENT LLC | Reduced | -384.1k |
| GOLDMAN SACHS GROUP INC | Reduced | -344.9k |
| Cubist Systematic Strategies, LLC | Reduced | -284.7k |
| MARSHALL WACE, LLP | Sold out | -222.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | -162.3k |
| Jain Global LLC | Sold out | -85.7k |
Biggest calls
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Added | $204.3k185.7k shares |
| CITADEL ADVISORS LLC | New | $52.7k47.9k shares |
| GROUP ONE TRADING LLC | Reduced | $43.1k39.2k shares |
| SIMPLEX TRADING, LLC | Added | $34.0k31.5k shares |
| JANE STREET GROUP, LLC | New | $11.3k10.3k shares |
Biggest puts
| CITADEL ADVISORS LLC | New | $110.2k100.2k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | $73.5k66.8k shares |
| SIMPLEX TRADING, LLC | Added | $57.0k52.7k shares |
| GROUP ONE TRADING LLC | Added | $27.9k25.4k shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| JANUS HENDERSON GROUP PLC 13G · institution +0.5 pts · filed 2025-11-14 | 12.1% |
| BIOTECHNOLOGY VALUE FUND L P 13G · passive investor +1.0 pts · filed 2026-08-14 | 10.0% |
| Adimab, LLC 13D · may seek influence -1.5 pts · filed 2025-12-29 | 7.3% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor -2.9 pts · filed 2026-05-15 | 7.0% |
| MAVERICK CAPITAL LTD 13G · passive investor -1.8 pts · filed 2026-02-13 | 6.7% |
| PERCEPTIVE ADVISORS LLC 13G · passive investor -1.6 pts · filed 2026-08-14 | 6.3% |
| BlackRock, Inc. 13G · institution new · filed 2026-07-28 | 5.5% |
Fell to 5% or below in the last year: Point72 Asset Management, L.P. (0.0%, 2026-05-15), Soleus Private Equity Fund III, L.P. (2.8%, 2026-02-12)
Insider purchases and sales in Q3 2025
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2023 | 0 | — | 0 | — | — |
| Q1 2024 | 0 | — | 0 | — | — |
| Q2 2024 | 0 | — | 1 | $186.6k | — |
| Q3 2024 | 0 | — | 0 | — | — |
| Q4 2024 | 0 | — | 1 | $836.0k | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 5 | $107.4k | $107.4k |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2025-08-19 | Andersen Jill Chief Legal Officer, Secretary | Sold plan | $28.2k49.4k shares |
| 2025-08-19 | Green Julie Chief Human Resources Officer | Sold plan | $16.9k29.6k shares |
| 2025-08-19 | Duke William E. Chief Financial Officer | Sold plan | $16.9k29.6k shares |
| 2025-08-19 | Lee Timothy Edward Chief Commercial Officer | Sold plan | $16.9k29.6k shares |
| 2025-08-19 | Allen Robert D. III Chief Scientific Officer | Sold plan | $15.6k27.4k shares |
| 2025-08-18 | Andersen Jill Chief Legal Officer, Secretary | Sold plan | $21.7k33.4k shares |
| 2025-08-18 | Lee Timothy Edward Chief Commercial Officer | Sold plan | $13.0k20.0k shares |
| 2025-08-18 | Green Julie Chief Human Resources Officer | Sold plan | $13.0k20.0k shares |
| 2025-08-18 | Duke William E. Chief Financial Officer | Sold plan | $13.0k20.0k shares |
| 2025-08-18 | Allen Robert D. III Chief Scientific Officer | Sold plan | $12.0k18.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q3 2025
| Manager | Shares | Change |
|---|---|---|
| JANUS HENDERSON GROUP PLC 0.01% of their portfolio | 25.4m $28.0m | New |
| Point72 Asset Management, L.P. 0.05% of their portfolio | 20.3m $22.3m | New |
| MAVERICK CAPITAL LTD 0.28% of their portfolio | 19.0m $20.9m | Added +8.7m |
| RA CAPITAL MANAGEMENT, L.P. 0.23% of their portfolio | 17.1m $18.8m | New |
| Mithril II GP LP 19.18% of their portfolio | 11.2m $12.4m | Unchanged |
| Driehaus Capital Management LLC 0.08% of their portfolio | 10.1m $11.1m | New |
| M28 Capital Management LP 14.96% of their portfolio | 9.2m $10.2m | Unchanged |
| ADAR1 Capital Management, LLC 0.80% of their portfolio | 7.4m $8.1m | New |
| 683 Capital Management, LLC 0.63% of their portfolio | 6.3m $6.9m | Added +3.2m |
| VANGUARD GROUP INC 0.00% of their portfolio | 5.8m $6.3m | Added +1.8m |
| Redmile Group, LLC 0.24% of their portfolio | 2.3m $2.5m | Unchanged |
| Ikarian Capital, LLC 0.46% of their portfolio | 2.1m $2.3m | New |
| Eversept Partners, LP 0.17% of their portfolio | 2.0m $2.3m | New |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 1.4m $1.6m | Added +197.5k |
| BOOTHBAY FUND MANAGEMENT, LLC 0.02% of their portfolio | 812.7k $894.0k | New |
| GSA CAPITAL PARTNERS LLP 0.07% of their portfolio | 805.2k $886.0k | Added +369.9k |
| MORGAN STANLEY 0.00% of their portfolio | 780.1k $858.1k | Added +266.7k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 765.4k $842.0k | Added +559.8k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 732.3k $805.9k | Added +95.4k |
| BlackRock, Inc. 0.00% of their portfolio | 718.9k $790.8k | Reduced -967.7k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 585.4k $643.9k | Unchanged |
| BARCLAYS PLC 0.00% of their portfolio | 433.5k $476.9k | Added +400.0k |
| TANG CAPITAL MANAGEMENT LLC 0.02% of their portfolio | 400.0k $440.0k | Unchanged |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 335.0k $368.5k | Added +96.3k |
| STATE STREET CORP 0.00% of their portfolio | 324.6k $357.1k | Added +51.8k |
| STEMPOINT CAPITAL LP 0.06% of their portfolio | 278.6k $306.5k | New |
| XTX Topco Ltd 0.01% of their portfolio | 238.5k $262.4k | Added +180.7k |
| Invesco Ltd. 0.00% of their portfolio | 175.2k $192.7k | Added +38.4k |
| FMR LLC 0.00% of their portfolio | 143.0k $157.3k | Reduced -4.4k |
| UBS Group AG 0.00% of their portfolio | 134.1k $147.5k | Reduced -854.0k |
| NORTHERN TRUST CORP 0.00% of their portfolio | 110.9k $122.0k | Unchanged |
| Squarepoint Ops LLC 0.00% of their portfolio | 107.8k $118.6k | Added +70.5k |
| Graham Capital Management, L.P. 0.00% of their portfolio | 107.4k $118.2k | New |
| Knott David M Jr 0.05% of their portfolio | 100.0k $110.0k | New |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 99.2k $109.1k | New |
| UNITED CAPITAL FINANCIAL ADVISORS, LLC 0.00% of their portfolio | 96.5k $106.2k | Unchanged |
| Jefferies Financial Group Inc. 0.00% of their portfolio | 92.3k $101.5k | New |
| a16z Perennial Management, L.P. 0.01% of their portfolio | 79.9k $87.9k | Unchanged |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 67.0k $73.7k | Reduced -162.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 49.3k $54.2k | Added +37.8k |
| CITIGROUP INC 0.00% of their portfolio | 46.3k $50.9k | Added +43.4k |
| Quadrature Capital Ltd 0.00% of their portfolio | 46.0k $50.6k | New |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 42.9k $47.2k | Reduced -344.9k |
| Cubist Systematic Strategies, LLC 0.00% of their portfolio | 42.0k $46.2k | Reduced -284.7k |
| Vanguard Personalized Indexing Management, LLC 0.00% of their portfolio | 39.6k $43.6k | Reduced -325 |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 39.4k $43.4k | Reduced -384.1k |
| Miller Financial Services LLC 0.05% of their portfolio | 37.0k $40.7k | Added +13.0k |
| TWO SIGMA SECURITIES, LLC 0.01% of their portfolio | 34.6k $38.0k | New |
| Point72 Asia (Singapore) Pte. Ltd. 0.00% of their portfolio | 28.4k $31.2k | Reduced -28.2k |
| GROUP ONE TRADING LLC 0.00% of their portfolio | 26.0k $28.7k | New |
| Militia Capital Partners, LP 0.00% of their portfolio | 25.0k $27.5k | New |
| OXFORD FINANCIAL GROUP, LTD. LLC 0.00% of their portfolio | 23.1k $25.4k | Unchanged |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 22.6k $24.0k | Added +21.4k |
| LAZARD ASSET MANAGEMENT LLC 0.00% of their portfolio | 20.9k $23.0k | New |
| VICTORY CAPITAL MANAGEMENT INC 0.00% of their portfolio | 19.1k $21.0k | New |
| Scientech Research LLC 0.01% of their portfolio | 14.0k $15.5k | New |
| Ethic Inc. 0.00% of their portfolio | 11.7k $12.9k | Reduced -16.8k |
| DGS Capital Management, LLC 0.00% of their portfolio | 11.3k $12.4k | New |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 10.6k $11.7k | Reduced -4.6k |
| NAPLES GLOBAL ADVISORS, LLC 0.00% of their portfolio | 10.0k $11.0k | Unchanged |
| Sunbelt Securities, Inc. 0.00% of their portfolio | 7.5k $8.2k | New |
| Global Retirement Partners, LLC 0.00% of their portfolio | 4.0k $4.4k | New |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 3.3k $3.0k | Added +2.2k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 3.2k $3.5k | Reduced -8.7k |
| CWM, LLC 0.00% of their portfolio | 3.1k $3.0k | Reduced -32.0k |
| Rise Advisors, LLC 0.00% of their portfolio | 1.7k $1.8k | Unchanged |
| Arax Advisory Partners 0.00% of their portfolio | 1.3k $1.5k | New |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 1.1k $1.2k | Unchanged |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 1.0k $1.1k | Reduced -2.8k |
| NISA INVESTMENT ADVISORS, LLC 0.00% of their portfolio | 889 $978 | Reduced -400 |
| EverSource Wealth Advisors, LLC 0.00% of their portfolio | 514 $565 | Added +405 |
| PNC Financial Services Group, Inc. 0.00% of their portfolio | 502 $553 | Reduced -381 |
| Rockefeller Capital Management L.P. 0.00% of their portfolio | 500 $550 | New |
| Parallel Advisors, LLC 0.00% of their portfolio | 496 $546 | Unchanged |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 250 $275 | Reduced -1.8k |
| Optiver Holding B.V. 0.00% of their portfolio | 96 $106 | New |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 19 $17 | Added +2 |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 1 $1 | Unchanged |