Vault-13

ADAGENE INC ADAG

ADS · ADR · CUSIP 005329107

36 institutional holders +11 vs Q1 2026
19,261,57119.3m shares reported held*
$81.0mreported value*
16 new 10 added 6 reduced 5 sold out net bought ≈ $39.9m (+9.5m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Implied quarter-end price ≈ $4.21.

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

02040Q3 22: 12Q4 22: 10Q1 23: 12Q2 23: 11Q3 23: 11Q4 23: 12Q1 24: 18Q2 24: 15Q3 24: 14Q4 24: 16Q1 25: 15Q2 25: 16Q3 25: 17Q4 25: 17Q1 26: 25Q2 26: 3636Q3 22Q3 23Q3 24Q3 25Q2 26
Numbers
QuarterHolders
Q3 202212
Q4 202210
Q1 202312
Q2 202311
Q3 202311
Q4 202312
Q1 202418
Q2 202415
Q3 202414
Q4 202416
Q1 202515
Q2 202516
Q3 202517
Q4 202517
Q1 202625
Q2 202636

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
40040Q3 24: 3 bought or addedQ3 24: 5 cut or sold outQ4 24: 8 bought or addedQ4 24: 2 cut or sold outQ4 24Q1 25: 3 bought or addedQ1 25: 8 cut or sold outQ2 25: 6 bought or addedQ2 25: 5 cut or sold outQ2 25Q3 25: 5 bought or addedQ3 25: 7 cut or sold outQ4 25: 7 bought or addedQ4 25: 7 cut or sold outQ4 25Q1 26: 13 bought or addedQ1 26: 9 cut or sold outQ2 26: 26 bought or addedQ2 26: 11 cut or sold outQ2 26
Numbers
QuarterBought or addedCut or sold out
Q3 202435
Q4 202482
Q1 202538
Q2 202565
Q3 202557
Q4 202577
Q1 2026139
Q2 20262611

Biggest buyers

DEERFIELD MANAGEMENT COMPANY, L.P. New +2,666,666+2.7m
Siren, L.L.C. New +2,666,666+2.7m
Squadron Capital Management LLC New +1,250,000+1.2m
AMERIPRISE FINANCIAL INC Added +1,108,808+1.1m
CITADEL ADVISORS LLC New +506,934+506.9k
Dauntless Investment Group, LLC Added +502,455+502.5k
Birchview Capital, LP New +240,000+240.0k
MONETA GROUP INVESTMENT ADVISORS LLC New +200,000+200.0k
Pathstone Holdings, LLC New +199,610+199.6k
UBS Group AG Added +120,061+120.1k

Biggest sellers

Exome Asset Management LLC Reduced -248,552-248.6k
MORGAN STANLEY Reduced -58,187-58.2k
Persistent Asset Partners Ltd Sold out -35,126-35.1k
Alyeska Investment Group, L.P. Sold out -20,710-20.7k
NOMURA HOLDINGS INC Sold out -14,710-14.7k
Invesco Ltd. Reduced -4,179-4.2k
JANE STREET GROUP, LLC Reduced -2,939-2.9k
EverSource Wealth Advisors, LLC Sold out -2,473-2.5k
BARCLAYS PLC Sold out -400-400
JPMORGAN CHASE & CO Reduced -260-260

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
Luo Peter 13D · may seek influence -4.4 pts · filed 2026-06-08
Stated purposeOn May 23, 2025, Mr. Luo received 191,667 ordinary shares from Great Han Fortune LP for the benefit of Peter Luo, and Xiaohong She received 23,333 ordinary shares from Great Han Fortune LP for the benefit of Xiaohong She. On May 23, 2025, Mr. Luo and Xiaohong She transferred 191,667 and 23,333 ordinary shares respectively to HAN 2020 Irrevocable Trust, for estate planning purpose. Due to the operation of the Concert Party Agreement dated December 14, 2020 among members of Peter Luo-Acting-in-Concert-Group, Peter Luo may be deemed to acquire or dispose additional beneficial ownership from time to time due to the acquisition or disposal of beneficial ownership by the members of Peter Luo-Acting-in-Concert-Group. The Reporting Persons acquired the ordinary shares reported herein for invest… Full filing
11.2% -4.4 pts 9.4m 2026-06-08
JANUS HENDERSON GROUP PLC 13G · institution new · filed 2026-05-07 10.1% new 6.7m 2026-05-07
Smith Vincent C 13G · passive investor +1.8 pts · filed 2026-01-29 8.7% +1.8 pts 5.1m 2026-01-29
Chernett Jorey 13G · passive investor new · filed 2026-03-18 5.1% new 2.4m 2026-03-18

Fell to 5% or below in the last year: WuXi PharmaTech Healthcare Fund I L.P. (3.5%, 2026-08-14), GENERAL ATLANTIC, L.P. (0.0%, 2026-02-17), Panacea Innovation Ltd (3.8%, 2025-11-14)

Insider purchases and sales since 1 Apr 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
404Q4 24: 0 buyingQ4 24: 0 sellingQ1 25: 0 buyingQ1 25: 0 sellingQ1 25Q2 25: 0 buyingQ2 25: 0 sellingQ3 25: 0 buyingQ3 25: 0 sellingQ3 25Q4 25: 0 buyingQ4 25: 0 sellingQ1 26: 0 buyingQ1 26: 0 sellingQ1 26Q2 26: 0 buyingQ2 26: 0 sellingQ3 26: 3 buyingQ3 26: 0 sellingQ3 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20240—0——
Q1 20250—0——
Q2 20250—0——
Q3 20250—0——
Q4 20250—0——
Q1 20260—0——
Q2 20260—0——
Q3 20263$162.3k0——
DateInsiderTradeSharesPrice ValueTheir holding
2026-09-23 Tam Man Kin Chief Financial Officer, director · American Depositary Shares (ADSs) Bought 2,000 $3.00 $6.0k2.0k shares +20%
2026-09-16 Luo Peter Chief Executive Officer, director · American Depositary Shares (ADS) Bought 20,290 $3.15 $63.9k20.3k shares +30%
2026-08-14 DO CUONG V Director · American Depositary Shares (ADS) Bought 2,000 $3.75 $7.5k2.0k shares new
2026-08-05 Luo Peter Chief Executive Officer, director · American Depositary Shares (ADS) Bought 279 $3.65 $1.0k279 shares +<1%
2026-08-04 Luo Peter Chief Executive Officer, director · American Depositary Shares (ADS) Bought 22,966 $3.65 $83.8k23.0k shares +51%

Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Jupiter Topco LLC 0.01% of their portfolio NEW YORK, NY 6,666,6666.7m $28.1m $28.1m 0.01% First filing
2 DEERFIELD MANAGEMENT COMPANY, L.P. 0.12% of their portfolio New York, NY 2,666,6662.7m $11.2m $11.2m 0.12% New
3 Siren, L.L.C. 0.23% of their portfolio New York, NY 2,666,6662.7m $11.2m $11.2m 0.23% New
4 AMERIPRISE FINANCIAL INC 0.00% of their portfolio MINNEAPOLIS, MN 1,716,7111.7m $7.2m $7.2m 0.00% Added +1.1m +1,108,808
5 HSG Holding Ltd 0.47% of their portfolio NA, K3 1,343,3641.3m $5.6m $5.6m 0.47% Unchanged
6 Squadron Capital Management LLC 1.80% of their portfolio OAK BROOK, IL 1,250,0001.2m $5.2m $5.2m 1.80% New
7 Dauntless Investment Group, LLC 3.91% of their portfolio Milford, MI 537,230537.2k $2.3m $2.3m 3.91% Added +502.5k +502,455
8 CITADEL ADVISORS LLC 0.00% of their portfolio MIAMI, FL 506,934506.9k $2.1m $2.1m 0.00% New
9 Exome Asset Management LLC 1.27% of their portfolio NEW YORK, NY 488,293488.3k $2.1m $2.1m 1.27% Reduced -248.6k -248,552
10 Birchview Capital, LP 0.47% of their portfolio BURLINGTON, VT 240,000240.0k $1.0m $1.0m 0.47% New
11 MONETA GROUP INVESTMENT ADVISORS LLC 0.01% of their portfolio ST LOUIS, MO 200,000200.0k $840.0k $840.0k 0.01% New
12 Pathstone Holdings, LLC 0.00% of their portfolio ENGLEWOOD, NJ 199,610199.6k $838.4k $838.4k 0.00% New
13 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 146,500146.5k $615.3k $615.3k 0.00% Added +112.0k +111,967
14 UBS Group AG 0.00% of their portfolio ZURICH, V8 124,063124.1k $521.1k $521.1k 0.00% Added +120.1k +120,061
15 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 105,598105.6k $443.5k $443.5k 0.00% New
16 Quadrature Capital Ltd 0.00% of their portfolio LONDON, X0 80,48780.5k $338.0k $338.0k 0.00% Added +68.9k +68,870
17 MARSHALL WACE, LLP 0.00% of their portfolio LONDON, X0 69,10069.1k $290.2k $290.2k 0.00% New
18 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 42,94542.9k $180.4k $180.4k 0.00% Reduced -4.2k -4,179
19 SmartHarvest Portfolios, LLC 0.06% of their portfolio SEATTLE, WA 41,69441.7k $175.1k $175.1k 0.06% Added +1.4k +1,382
20 Kamunting Street Capital Management, L.P. 0.09% of their portfolio MIAMI BEACH, FL 38,07038.1k $160.0k $160.0k 0.09% Unchanged
21 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 27,48627.5k $115.4k $115.4k 0.00% Reduced -2.9k -2,939
22 HRT FINANCIAL LP 0.00% of their portfolio NEW YORK, NY 21,73521.7k $91.0k $91.0k 0.00% New
23 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 17,99418.0k $75.6k $75.6k 0.00% Added +7.7k +7,685
24 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 17,07017.1k $72.0k $72.0k 0.00% Added +220 +220
25 XTX Topco Ltd 0.00% of their portfolio LONDON, X0 12,27212.3k $51.5k $51.5k 0.00% New
26 TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio NEW YORK, NY 11,95312.0k $50.2k $50.2k 0.00% New
27 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 7,9618.0k $33.4k $33.4k 0.00% Reduced -58.2k -58,187
28 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 7,9007.9k $33.2k $33.2k 0.00% Added +4.2k +4,200
29 HUNTINGTON NATIONAL BANK 0.00% of their portfolio COLUMBUS, OH 2,4642.5k $10.3k $10.3k 0.00% New
30 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 1,5131.5k $6.4k $6.4k 0.00% New
31 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 1,0581.1k $4.4k $4.4k 0.00% New
32 BlackRock, Inc. 0.00% of their portfolio New York, NY 635635 $2.7k $2.7k 0.00% Unchanged
33 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 452452 $1.9k $1.9k 0.00% Reduced -260 -260
34 Integrated Wealth Concepts LLC 0.00% of their portfolio WALTHAM, MA 420420 $1.8k $1.8k 0.00% New
35 Caitong International Asset Management Co., Ltd 0.00% of their portfolio HONG KONG, K3 4848 $202 $202 0.00% Added +20 +20
36 SBI Securities Co., Ltd. 0.00% of their portfolio TOKYO, M0 1313 $55 $55 0.00% Reduced -56 -56