ACLARIS THERAPEUTICS INC ACRS
COM · Common Stock · CUSIP 00461U105
Company in St Louis, United States
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersWayne, PA
- Founded2012
- Websiteaclaristx.com
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 71.3m as of 2024-04-30, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.25. Options: 5 managers hold calls ($75.7k notional), 4 hold puts ($94.0k).
Trends to Q1 2024
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2022 | 127 |
| Q4 2022 | 129 |
| Q1 2023 | 150 |
| Q2 2023 | 134 |
| Q3 2023 | 139 |
| Q4 2023 | 108 |
| Q1 2024 | 99 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2022 | 53 | 49 |
| Q1 2023 | 85 | 58 |
| Q2 2023 | 64 | 69 |
| Q3 2023 | 81 | 50 |
| Q4 2023 | 64 | 78 |
| Q1 2024 | 45 | 66 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q2 2023 | $13.0m | $16.5m | 1.26 |
| Q3 2023 | $22.1m | $15.8m | 0.71 |
| Q4 2023 | $96.8k | $72.1k | 0.74 |
| Q1 2024 | $75.7k | $94.0k | 1.24 |
Biggest buyers
| BML Capital Management, LLC | Added | +8.7m |
| D. E. Shaw & Co., Inc. | Added | +1.3m |
| AQR CAPITAL MANAGEMENT LLC | New | +612.2k |
| Palo Alto Investors LP | New | +569.8k |
| Acuitas Investments, LLC | New | +461.7k |
| VANGUARD GROUP INC | Added | +207.4k |
| GEODE CAPITAL MANAGEMENT, LLC | Added | +171.5k |
| Man Group plc | Added | +146.4k |
| Connor, Clark & Lunn Investment Management Ltd. | New | +100.8k |
| Marquette Asset Management, LLC | New | +84.0k |
Biggest sellers
| CITADEL ADVISORS LLC | Reduced | -4.5m |
| Velan Capital Investment Management LP | Sold out | -1.8m |
| TANG CAPITAL MANAGEMENT LLC | Sold out | -1.8m |
| Monaco Asset Management SAM | Sold out | -979.4k |
| GSA CAPITAL PARTNERS LLP | Reduced | -908.9k |
| JACOBS LEVY EQUITY MANAGEMENT, INC | Sold out | -748.8k |
| BlackRock Inc. | Reduced | -703.7k |
| Bain Capital Life Sciences Investors, LLC | Reduced | -500.0k |
| CITIGROUP INC | Reduced | -495.2k |
| MORGAN STANLEY | Reduced | -476.8k |
Biggest calls
| CITADEL ADVISORS LLC | Added | $46.5k37.5k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $16.7k13.5k shares |
| SIMPLEX TRADING, LLC | Reduced | $8.0k6.8k shares |
| GROUP ONE TRADING LLC | Reduced | $4.5k3.6k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Biggest puts
| GROUP ONE TRADING LLC | Added | $54.8k44.2k shares |
| CITADEL ADVISORS LLC | Reduced | $19.7k15.9k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $19.5k15.7k shares |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. | Unchanged | $00 shares |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| BML Investment Partners, L.P. 13G · passive investor -2.0 pts · filed 2026-04-27 | 9.9% |
| Bonita Biotech (HK) Ltd 13G · passive investor filed 2026-01-09 | 9.4% |
| RA CAPITAL MANAGEMENT, L.P. 13G · passive investor +2.8 pts · filed 2026-08-14 | 9.1% |
| Deep Track Capital, LP 13G · passive investor new · filed 2026-03-17 | 7.0% |
| BlackRock, Inc. 13G · institution +1.1 pts · filed 2026-01-21 | 6.2% |
| Frazier Life Sciences Public Fund, L.P. 13G · passive investor new · filed 2026-09-21 | 5.4% |
Fell to 5% or below in the last year: Vivo Opportunity Fund Holdings, L.P. (4.3%, 2026-05-12), VANGUARD GROUP INC (0.0%, 2026-03-26)
Insider purchases and sales in Q1 2024
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q2 2022 | 0 | — | 3 | $1.8m | — |
| Q3 2022 | 0 | — | 0 | — | — |
| Q4 2022 | 0 | — | 2 | $3.5m | — |
| Q1 2023 | 1 | $99.8k | 4 | $2.4m | — |
| Q2 2023 | 0 | — | 1 | $61.7k | $61.7k |
| Q3 2023 | 2 | $175.0k | 1 | $43.9k | $43.9k |
| Q4 2023 | 0 | — | 1 | $30.5k | $30.5k |
| Q1 2024 | 1 | $18.0k | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2024-03-04 | Powell Andrew Kenneth William Director | Bought | $7.5k6.0k shares |
| 2024-03-01 | Powell Andrew Kenneth William Director | Bought | $10.5k8.5k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q1 2024
| Manager | Shares | Change |
|---|---|---|
| BML Capital Management, LLC 7.80% of their portfolio | 9.4m $11.7m | Added +8.7m |
| BlackRock Inc. 0.00% of their portfolio | 5.2m $6.5m | Reduced -703.7k |
| VANGUARD GROUP INC 0.00% of their portfolio | 4.9m $6.1m | Added +207.4k |
| D. E. Shaw & Co., Inc. 0.01% of their portfolio | 3.3m $4.1m | Added +1.3m |
| MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio | 3.3m $4.1m | Reduced -205.9k |
| Bain Capital Life Sciences Investors, LLC 0.30% of their portfolio | 3.0m $3.7m | Reduced -500.0k |
| Rock Springs Capital Management LP 0.09% of their portfolio | 2.8m $3.4m | Reduced -245.0k |
| ACADIAN ASSET MANAGEMENT LLC 0.01% of their portfolio | 2.1m $2.6m | Reduced -216.0k |
| RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio | 1.7m $2.1m | Reduced -73.0k |
| GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio | 1.6m $1.9m | Added +171.5k |
| MORGAN STANLEY 0.00% of their portfolio | 1.5m $1.8m | Reduced -476.8k |
| TWO SIGMA ADVISERS, LP 0.00% of their portfolio | 1.5m $1.8m | Added +30.1k |
| STATE STREET CORP 0.00% of their portfolio | 1.3m $1.7m | Reduced -50.0k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 1.3m $1.6m | Reduced -133.8k |
| Qube Research & Technologies Ltd 0.00% of their portfolio | 1.2m $1.5m | Reduced -467.6k |
| DEUTSCHE BANK AG\ 0.00% of their portfolio | 957.0k $1.2m | Added +23.0k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 930.0k $1.2m | Reduced -4.5m |
| SAMSARA BIOCAPITAL, LLC 0.13% of their portfolio | 696.2k $863.3k | Unchanged |
| GSA CAPITAL PARTNERS LLP 0.07% of their portfolio | 679.1k $842.0k | Reduced -908.9k |
| FMR LLC 0.00% of their portfolio | 671.8k $833.1k | Added +1.1k |
| AQR CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 612.2k $759.1k | New |
| Palo Alto Investors LP 0.08% of their portfolio | 569.8k $706.6k | New |
| NORTHERN TRUST CORP 0.00% of their portfolio | 562.2k $697.2k | Reduced -97.4k |
| Acuitas Investments, LLC 0.29% of their portfolio | 461.7k $572.5k | New |
| Aisling Capital Management LP 0.18% of their portfolio | 434.5k $538.7k | Unchanged |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio | 419.3k $520.0k | Reduced -17.0k |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 331.7k $411.4k | Added +72.4k |
| HighTower Advisors, LLC 0.00% of their portfolio | 312.6k $386.0k | Reduced -30.4k |
| STRS OHIO 0.00% of their portfolio | 264.7k $328.0k | Added +71.7k |
| Frazier Life Sciences Management, L.P. 0.01% of their portfolio | 264.4k $327.8k | Unchanged |
| Man Group plc 0.00% of their portfolio | 247.7k $307.1k | Added +146.4k |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 241.1k $299.0k | Added +23.7k |
| Bank of New York Mellon Corp 0.00% of their portfolio | 232.8k $288.6k | Reduced -49.6k |
| Nuveen Asset Management, LLC 0.00% of their portfolio | 166.7k $206.7k | Reduced -273.2k |
| GOLDMAN SACHS GROUP INC 0.00% of their portfolio | 145.8k $180.8k | Reduced -375.1k |
| JPMORGAN CHASE & CO 0.00% of their portfolio | 139.3k $172.8k | Added +190 |
| GROUP ONE TRADING LLC 0.01% of their portfolio | 133.8k $165.9k | Added +56.6k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 123.5k $153.1k | Reduced -30.1k |
| XTX Topco Ltd 0.02% of their portfolio | 123.1k $152.6k | Reduced -255.2k |
| PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio | 109.8k $137.0k | Added +1.3k |
| Connor, Clark & Lunn Investment Management Ltd. 0.00% of their portfolio | 100.8k $125.0k | New |
| RHUMBLINE ADVISERS 0.00% of their portfolio | 97.2k $120.5k | Added +1.5k |
| DIMENSIONAL FUND ADVISORS LP 0.00% of their portfolio | 89.1k $110.4k | Reduced -98.5k |
| Marquette Asset Management, LLC 0.02% of their portfolio | 84.0k $104.1k | New |
| Deuterium Capital Management, LLC 0.18% of their portfolio | 80.0k $99.2k | New |
| UBS Group AG 0.00% of their portfolio | 70.4k $87.3k | Added +50.8k |
| BARCLAYS PLC 0.00% of their portfolio | 68.3k $84.7k | Reduced -107.7k |
| AMERIPRISE FINANCIAL INC 0.00% of their portfolio | 63.0k $78.1k | Reduced -1.8k |
| Russell Investments Group, Ltd. 0.00% of their portfolio | 62.8k $77.8k | Added +61.6k |
| ALLIANCEBERNSTEIN L.P. 0.00% of their portfolio | 60.4k $74.9k | Unchanged |
| BBR PARTNERS, LLC 0.01% of their portfolio | 60.0k $74.4k | New |
| Engineers Gate Manager LP 0.00% of their portfolio | 57.1k $70.9k | Reduced -22.7k |
| Verition Fund Management LLC 0.00% of their portfolio | 53.8k $66.8k | New |
| HSBC HOLDINGS PLC 0.00% of their portfolio | 46.4k $57.5k | New |
| Cubist Systematic Strategies, LLC 0.00% of their portfolio | 44.9k $55.7k | Reduced -90.4k |
| Cambridge Investment Research Advisors, Inc. 0.00% of their portfolio | 41.9k $52.0k | Unchanged |
| Mariner, LLC 0.00% of their portfolio | 39.8k $49.4k | Added +3.1k |
| AMERICAN INTERNATIONAL GROUP, INC. 0.00% of their portfolio | 34.2k $42.4k | Reduced -294 |
| TUDOR INVESTMENT CORP ET AL 0.00% of their portfolio | 33.2k $41.1k | Unchanged |
| SG Americas Securities, LLC 0.00% of their portfolio | 32.8k $41.0k | Added +13.5k |
| Mirae Asset Global Investments Co., Ltd. 0.00% of their portfolio | 31.6k $239.4k | New |
| HARBOR CAPITAL ADVISORS, INC. 0.00% of their portfolio | 31.0k $38.0k | New |
| Invesco Ltd. 0.00% of their portfolio | 30.5k $37.8k | Reduced -1.2k |
| SIMPLEX TRADING, LLC 0.00% of their portfolio | 28.1k $34.0k | New |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 25.9k $32.1k | Added +5.8k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 25.6k $31.8k | Reduced -99.7k |
| Vontobel Holding Ltd. 0.00% of their portfolio | 20.0k $24.8k | Reduced -10.3k |
| STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM 0.00% of their portfolio | 18.7k $151.2k | Reduced -1.4k |
| PRINCIPAL FINANCIAL GROUP INC 0.00% of their portfolio | 17.7k $21.9k | Reduced -1.8k |
| ProShare Advisors LLC 0.00% of their portfolio | 17.4k $21.6k | Added +1.4k |
| TWO SIGMA SECURITIES, LLC 0.00% of their portfolio | 16.1k $20.0k | New |
| ALGERT GLOBAL LLC 0.00% of their portfolio | 15.8k $19.6k | New |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio | 14.8k $18.3k | Reduced -1.2k |
| Marex Group Ltd 0.00% of their portfolio | 14.4k $17.9k | Unchanged |
| China Universal Asset Management Co., Ltd. 0.00% of their portfolio | 13.6k $16.9k | Added +5.4k |
| Blackstone Inc. 0.00% of their portfolio | 13.0k $16.2k | Unchanged |
| NEUBERGER BERMAN GROUP LLC 0.00% of their portfolio | 12.5k $15.5k | Reduced -5.7k |
| CITIGROUP INC 0.00% of their portfolio | 12.3k $15.3k | Reduced -495.2k |
| Jefferies Financial Group Inc. 0.00% of their portfolio | 11.5k $14.3k | Unchanged |
| FNY Investment Advisers, LLC 0.01% of their portfolio | 10.0k $12.0k | New |
| Legal & General Group Plc 0.00% of their portfolio | 9.6k $12.0k | Reduced -40.2k |
| FEDERATED HERMES, INC. 0.00% of their portfolio | 8.3k $10.2k | Added +3.7k |
| NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio | 7.7k $9.6k | Added +549 |
| CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio | 7.0k $8.7k | Reduced -48.6k |
| Ameritas Investment Partners, Inc. 0.00% of their portfolio | 6.9k $8.6k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 5.3k $6.5k | Reduced -4.5k |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 3.0k $4.0k | Reduced -20.4k |
| AMALGAMATED BANK 0.00% of their portfolio | 2.3k $3.0k | Reduced -7.5k |
| Halpern Financial, Inc. 0.00% of their portfolio | 1.5k $1.9k | Unchanged |
| Cornerstone Planning Group LLC 0.00% of their portfolio | 580 $789 | New |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO 0.00% of their portfolio | 500 $620 | Unchanged |
| Daiwa Securities Group Inc. 0.00% of their portfolio | 248 $0 | Unchanged |
| Truvestments Capital LLC 0.00% of their portfolio | 150 $186 | Unchanged |
| OSAIC HOLDINGS, INC. 0.00% of their portfolio | 124 $154 | New |
| Farther Finance Advisors, LLC 0.00% of their portfolio | 99 $125 | Added +34 |
| CWM, LLC 0.00% of their portfolio | 77 $0 | Added +29 |
| Covestor Ltd 0.00% of their portfolio | 63 $0 | Added +49 |
| Avior Wealth Management, LLC 0.00% of their portfolio | 14 $17 | New |
| CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio | 0 $0 | Unchanged |