Vault-13

ACHIEVE LIFE SCIENCES INC ACHV

COM · Common Stock · CUSIP 004468500

57 institutional holders +15 vs Q1 2024
19,027,41919.0m shares reported held*
55.4% of all shares outstanding*
$80.5mreported value*
23 new 14 added 8 reduced 9 sold out net bought ≈ $13.0m (+2.8m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once ($1.0m this quarter). Holder counts are more reliable. Shares outstanding: 34.3m as of 2024-08-13, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $4.24. Options: 8 managers hold calls ($2.7m notional), 3 hold puts ($115.6k).

Trends to Q2 2024

Institutional holders

Managers reporting a position, each quarter

0204060Q3 22: 29Q4 22: 29Q1 23: 32Q2 23: 40Q3 23: 36Q4 23: 30Q1 24: 42Q2 24: 5757Q3 22Q1 23Q3 23Q1 24Q2 24
Numbers
QuarterHolders
Q3 202229
Q4 202229
Q1 202332
Q2 202340
Q3 202336
Q4 202330
Q1 202442
Q2 202457

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
40040Q4 22: 12 bought or addedQ4 22: 13 cut or sold outQ4 22Q1 23: 20 bought or addedQ1 23: 11 cut or sold outQ2 23: 25 bought or addedQ2 23: 13 cut or sold outQ2 23Q3 23: 13 bought or addedQ3 23: 21 cut or sold outQ4 23: 13 bought or addedQ4 23: 17 cut or sold outQ4 23Q1 24: 25 bought or addedQ1 24: 16 cut or sold outQ2 24: 37 bought or addedQ2 24: 17 cut or sold outQ2 24
Numbers
QuarterBought or addedCut or sold out
Q4 20221213
Q1 20232011
Q2 20232513
Q3 20231321
Q4 20231317
Q1 20242516
Q2 20243717

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$1m$2m$3mQ3 23 calls: $110.9kQ3 23 puts: $251.6kQ3 23P/C 2.27Q4 23 calls: $119.7kQ4 23 puts: $209.3kQ4 23P/C 1.75Q1 24 calls: $1.6mQ1 24 puts: $225.5kQ1 24P/C 0.14Q2 24 calls: $2.7mQ2 24 puts: $115.6kQ2 24P/C 0.04
Numbers
QuarterCallsPutsP/C
Q3 2023$110.9k$251.6k2.27
Q4 2023$119.7k$209.3k1.75
Q1 2024$1.6m$225.5k0.14
Q2 2024$2.7m$115.6k0.04

Biggest buyers

BlackRock Inc. Added +1,904,079+1.9m
Nantahala Capital Management, LLC Added +654,000+654.0k
VANGUARD GROUP INC Added +557,290+557.3k
GEODE CAPITAL MANAGEMENT, LLC Added +493,851+493.9k
STATE STREET CORP Added +348,885+348.9k
Bank of New York Mellon Corp New +102,555+102.6k
CHARLES SCHWAB INVESTMENT MANAGEMENT INC New +95,886+95.9k
FRANKLIN RESOURCES INC Added +88,286+88.3k
Nuveen Asset Management, LLC New +46,668+46.7k
RHUMBLINE ADVISERS New +41,818+41.8k

Biggest sellers

Altium Capital Management LLC Reduced -619,160-619.2k
CVI Holdings, LLC Reduced -495,443-495.4k
ADAR1 Capital Management, LLC Reduced -332,767-332.8k
MILLENNIUM MANAGEMENT LLC Reduced -175,343-175.3k
Sofinnova Investments, Inc. Reduced -129,858-129.9k
SUSQUEHANNA INTERNATIONAL GROUP, LLP Sold out -44,653-44.7k
Balyasny Asset Management L.P. Sold out -27,747-27.7k
Virtu Financial LLC Sold out -12,930-12.9k
OMERS ADMINISTRATION Corp Sold out -12,000-12.0k
Jefferies Financial Group Inc. Sold out -11,500-11.5k

Biggest calls

GROUP ONE TRADING LLC Added $861.0k183.2k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Reduced $592.2k126.0k shares
Caption Management, LLC New $506.2k107.7k shares
CITADEL ADVISORS LLC Added $305.5k65.0k shares
SIMPLEX TRADING, LLC Reduced $283.0k60.3k shares
JANE STREET GROUP, LLC New $94.0k20.0k shares
HAP Trading, LLC New $32.0k80.0k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Biggest puts

GROUP ONE TRADING LLC Reduced $94.0k20.0k shares
CITADEL ADVISORS LLC Reduced $21.6k4.6k shares
CONCOURSE FINANCIAL GROUP SECURITIES, INC. Unchanged $00 shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
TPG GP A, LLC 13D · may seek influence new · filed 2026-04-24
Stated purposeThe information set forth in or incorporated by reference in Items 2, 3, 5 and 6 of this Schedule 13D is incorporated by reference in its entirety into this Item 4. Securities Purchase Agreement TPG Auriga entered into a Securities Purchase Agreement (the "Securities Purchase Agreement") with the Issuer, dated as of April 15, 2026, pursuant to which it agreed to purchase, and the Issuer agreed to sell and issue, 6,877,580 shares of Common Stock and 6,877,580 accompanying Warrants at a collective price of $3.635 per combination of share of Common Stock and accompany Warrant (the "Private Placement"). On April 17, 2026, the Private Placement closed (the "Closing"). The aggregate purchase price of $25,000,003.30 paid by TPG Auriga for the shares of Common Stock and accompanying Warrants w… Full filing
12.6% new 13.8m≈ $89.8m 2026-04-24
Logos Global Management LP 13G · institution new · filed 2026-08-17 10.0% new 10.5m≈ $68.8m 2026-08-17
venBio Global Strategic Fund V, L.P. 13D · may seek influence new · filed 2026-04-27
Stated purposeThe response to Item 3 of this Schedule 13D is incorporated herein by reference. The Reporting Persons acquired the securities reported herein for investment purposes. Subject to a number of factors, including market conditions and their general investment and trading policies, the Reporting Persons may, in the ordinary course of their business, dispose of the shares of Common Stock that they beneficially own. These dispositions may occur in open market transactions, privately negotiated transactions, or through other methods. Additionally, Fund V may distribute the shares of Common Stock that it directly holds to its limited partners. Dr. Royston, who is a member of General Partner V, is a director of the Issuer. The Reporting Persons, either directly or indirectly through Dr. Roys… Full filing
10.0% new 10.7m≈ $70.1m 2026-04-27
Paradigm Biocapital Advisors LP 13G · passive investor new · filed 2026-04-24 9.2% new 9.9m≈ $64.7m 2026-04-24
FRANKLIN RESOURCES INC 13G · institution +2.1 pts · filed 2026-07-28 8.3% +2.1 pts 8.9m≈ $58.0m 2026-07-28
Frazier Life Sciences Public Fund, L.P. 13G · passive investor new · filed 2026-04-24 6.5% new 6.6m≈ $43.3m 2026-04-24
Alyeska Investment Group, L.P. 13G · institution -4.3 pts · filed 2025-11-14 5.6% -4.3 pts 3.0m≈ $19.5m 2025-11-14
Janus Henderson Group Ltd. 13G · institution new · filed 2026-08-13 5.4% new 5.5m≈ $35.9m 2026-08-13
Venrock Healthcare Capital Partners III, L.P. 13G · passive investor new · filed 2026-04-24 5.2% new 5.5m≈ $35.9m 2026-04-24
BlackRock, Inc. 13G · institution +4.5 pts · filed 2026-07-27 5.1% +4.5 pts 5.3m≈ $34.4m 2026-07-27
Vivo Opportunity Fund Holdings, L.P. 13G · passive investor new · filed 2026-07-08 5.0% new 5.3m≈ $34.6m 2026-07-08

Insider purchases and sales in Q2 2024

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
202Q3 22: 0 buyingQ3 22: 0 sellingQ4 22: 1 buyingQ4 22: 0 sellingQ4 22Q1 23: 0 buyingQ1 23: 0 sellingQ2 23: 1 buyingQ2 23: 0 sellingQ2 23Q3 23: 0 buyingQ3 23: 0 sellingQ4 23: 0 buyingQ4 23: 0 sellingQ4 23Q1 24: 2 buyingQ1 24: 0 sellingQ2 24: 0 buyingQ2 24: 0 sellingQ2 24
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q3 20220—0——
Q4 20221—0——
Q1 20230—0——
Q2 20231$27.5k0——
Q3 20230—0——
Q4 20230—0——
Q1 20242$45.9k0——
Q2 20240—0——

None reported in Q2 2024.

Holders, Q2 2024

#ManagerLocationShares Value% of their portfolioChangeShares change
1 FRANKLIN RESOURCES INC 0.01% of their portfolio San Mateo, CA 6,052,3746.1m $19.6m $19.6m 0.01% Added +88.3k +88,286
2 Propel Bio Management, LLC 7.48% of their portfolio Los Angeles, CA 2,453,0922.5m $11.5m $11.5m 7.48% Unchanged
3 BlackRock Inc. 0.00% of their portfolio New York, NY 1,956,5102.0m $9.2m $9.2m 0.00% Added +1.9m +1,904,079
4 VANGUARD GROUP INC 0.00% of their portfolio Valley Forge, PA 1,505,7311.5m $7.1m $7.1m 0.00% Added +557.3k +557,290
5 Sofinnova Investments, Inc. 0.41% of their portfolio Menlo Park, CA 1,388,3721.4m $6.5m $6.5m 0.41% Reduced -129.9k -129,858
6 Nantahala Capital Management, LLC 0.31% of their portfolio NEW CANAAN, CT 1,308,0001.3m $6.1m $6.1m 0.31% Added +654.0k +654,000
7 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 700,635700.6k $3.3m $3.3m 0.00% Added +493.9k +493,851
8 ADAR1 Capital Management, LLC 0.51% of their portfolio AUSTIN, TX 542,233542.2k $2.5m $2.5m 0.51% Reduced -332.8k -332,767
9 Alyeska Investment Group, L.P. 0.01% of their portfolio CHICAGO, IL 471,000471.0k $2.2m $2.2m 0.01% Unchanged
10 Shay Capital LLC 0.59% of their portfolio NEW YORK, NY 450,000450.0k $2.1m $2.1m 0.59% Unchanged
11 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 404,101404.1k $1.9m $1.9m 0.00% Added +348.9k +348,885
12 Long Focus Capital Management, LLC 0.12% of their portfolio SAN JUAN, PR 248,099248.1k $1.2m $1.2m 0.12% Unchanged
13 Simplify Asset Management Inc. 0.09% of their portfolio Las Vegas, NV 217,845217.8k $1.0m $1.0m 0.09% Unchanged
14 Altium Capital Management LLC 0.42% of their portfolio NEW YORK, NY 216,310216.3k $1.0m $1.0m 0.42% Reduced -619.2k -619,160
15 LPL Financial LLC 0.00% of their portfolio FORT MILL, SC 188,000188.0k $883.6k $883.6k 0.00% Added +5.5k +5,500
16 RAYMOND JAMES & ASSOCIATES 0.00% of their portfolio ST PETERSBURG, FL 150,449150.4k $707.1k $707.1k 0.00% Reduced -1.4k -1,400
17 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 126,273126.3k $593.5k $593.5k 0.00% Added +27.5k +27,541
18 Bank of New York Mellon Corp 0.00% of their portfolio NEW YORK, NY 102,555102.6k $482.0k $482.0k 0.00% New
19 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 0.00% of their portfolio SAN FRANCISCO, CA 95,88695.9k $450.7k $450.7k 0.00% New
20 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 75,88075.9k $356.6k $356.6k 0.00% Added +7.1k +7,075
21 CVI Holdings, LLC 0.29% of their portfolio WILMINGTON, DE 71,74971.7k $337.2k $337.2k 0.29% Reduced -495.4k -495,443
22 Nuveen Asset Management, LLC 0.00% of their portfolio CHICAGO, IL 46,66846.7k $219.3k $219.3k 0.00% New
23 RHUMBLINE ADVISERS 0.00% of their portfolio BOSTON, MA 41,81841.8k $196.5k $196.5k 0.00% New
24 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 34,53834.5k $162.3k $162.3k 0.00% Added +12.3k +12,320
25 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 32,77732.8k $154.1k $154.1k 0.00% New
26 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 29,35429.4k $138.0k $138.0k 0.00% New
27 BANK OF AMERICA CORP /DE/ 0.00% of their portfolio CHARLOTTE, NC 26,34226.3k $123.8k $123.8k 0.00% Added +4.0k +3,987
28 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 25,06025.1k $117.8k $117.8k 0.00% Added +14.4k +14,360
29 J. Goldman & Co LP 0.00% of their portfolio NEW YORK, NY 24,54824.5k $115.4k $115.4k 0.00% Unchanged
30 DEUTSCHE BANK AG\ 0.00% of their portfolio FRANKFURT AM MAIN, 2M 22,86522.9k $107.5k $107.5k 0.00% New
31 NEW YORK STATE COMMON RETIREMENT FUND 0.00% of their portfolio ALBANY, NY 21,60021.6k $101.5k $101.5k 0.00% New
32 MANCHESTER FINANCIAL INC 0.02% of their portfolio Westlake Village, CA 19,63019.6k $92.3k $92.3k 0.02% Added +530 +530
33 Corebridge Financial, Inc. 0.00% of their portfolio HOUSTON, TX 18,52918.5k $87.3k $87.3k 0.00% First filing
34 MILLENNIUM MANAGEMENT LLC 0.00% of their portfolio NEW YORK, NY 18,29518.3k $86.0k $86.0k 0.00% Reduced -175.3k -175,343
35 BERKSHIRE ASSET MANAGEMENT LLC/PA 0.00% of their portfolio WILKES BARRE, PA 17,70017.7k $83.2k $83.2k 0.00% New
36 Invesco Ltd. 0.00% of their portfolio ATLANTA, GA 16,21416.2k $76.2k $76.2k 0.00% New
37 MANUFACTURERS LIFE INSURANCE COMPANY, THE 0.00% of their portfolio Toronto, A6 14,64114.6k $68.8k $68.8k 0.00% New
38 VOYA INVESTMENT MANAGEMENT LLC 0.00% of their portfolio ATLANTA, GA 13,23413.2k $62.2k $62.2k 0.00% New
39 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 11,82311.8k $55.6k $55.6k 0.00% New
40 PRICE T ROWE ASSOCIATES INC /MD/ 0.00% of their portfolio BALTIMORE, MD 11,08511.1k $0 $0 0.00% New
41 UBS Group AG 0.00% of their portfolio ZURICH, V8 10,45010.4k $49.1k $49.1k 0.00% Added +10.4k +10,448
42 Madison Park Capital Advisors, LLC 0.04% of their portfolio SEATTLE, WA 10,00010.0k $47.0k $47.0k 0.04% Unchanged
43 MetLife Investment Management, LLC 0.00% of their portfolio Whippany, NJ 9,0549.1k $42.6k $42.6k 0.00% New
44 CITIGROUP INC 0.00% of their portfolio NEW YORK, NY 7,5877.6k $35.7k $35.7k 0.00% New
45 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 7,2807.3k $34.2k $34.2k 0.00% Reduced -2.6k -2,572
46 STRS OHIO 0.00% of their portfolio COLUMBUS, OH 6,4006.4k $30.1k $30.1k 0.00% New
47 Legal & General Group Plc 0.00% of their portfolio London, X0 3,4843.5k $16.4k $16.4k 0.00% New
48 Ameritas Investment Partners, Inc. 0.00% of their portfolio LINCOLN, NE 3,3743.4k $15.9k $15.9k 0.00% New
49 ROYAL BANK OF CANADA 0.00% of their portfolio TORONTO, A6 3,2393.2k $15.0k $15.0k 0.00% New
50 Allworth Financial LP 0.00% of their portfolio FOLSOM, CA 3,0003.0k $13.9k $13.9k 0.00% New
51 Stephens Consulting, LLC 0.00% of their portfolio FLINT, MI 3,0003.0k $14.1k $14.1k 0.00% Unchanged
52 COMERICA BANK 0.00% of their portfolio DALLAS, TX 2,5002.5k $11.8k $11.8k 0.00% Unchanged
53 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 0.00% of their portfolio WEST SACRAMENTO, CA 2,4962.5k $11.7k $11.7k 0.00% New
54 AMALGAMATED BANK 0.00% of their portfolio NEW YORK, NY 1,1921.2k $6.0k $6.0k 0.00% New
55 Tower Research Capital LLC (TRC) 0.00% of their portfolio NEW YORK, NY 293293 $1.4k $1.4k 0.00% Reduced -2.8k -2,849
56 Cornerstone Planning Group LLC 0.00% of their portfolio FAIRFIELD, NJ 100100 $447 $447 0.00% Unchanged
57 CONCOURSE FINANCIAL GROUP SECURITIES, INC. 0.00% of their portfolio BIRMINGHAM, AL 00 $0 $0 0.00% Unchanged