Vault-13

TALPHERA INC TLPH

COM NEW · Common Stock · CUSIP 00444T209

Company in Redwood City, United States

49 institutional holders +4 vs Q1 2026
28,245,92128.2m shares reported held*
54.4% of all shares outstanding*
$29.1mreported value*
12 new 14 added 6 reduced 8 sold out net bought ≈ $6.6m (+6.4m shares)

* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 51.9m as of 2026-08-06, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $1.03. Options: 5 managers hold calls ($114.8k notional), 3 hold puts ($111.4k).

Trends to Q2 2026

Institutional holders

Managers reporting a position, each quarter

0204060Q4 22: 37Q1 23: 33Q2 23: 28Q3 23: 32Q4 23: 34Q1 24: 32Q2 24: 31Q3 24: 30Q4 24: 36Q1 25: 33Q2 25: 33Q3 25: 34Q4 25: 38Q1 26: 45Q2 26: 4949Q4 22Q4 23Q4 24Q4 25Q2 26
Numbers
QuarterHolders
Q4 202237
Q1 202333
Q2 202328
Q3 202332
Q4 202334
Q1 202432
Q2 202431
Q3 202430
Q4 202436
Q1 202533
Q2 202533
Q3 202534
Q4 202538
Q1 202645
Q2 202649

Buyers vs sellers

Managers adding to or starting a position, vs cutting or selling out

Bought or addedCut or sold out
40040Q3 24: 6 bought or addedQ3 24: 13 cut or sold outQ4 24: 12 bought or addedQ4 24: 11 cut or sold outQ4 24Q1 25: 13 bought or addedQ1 25: 13 cut or sold outQ2 25: 7 bought or addedQ2 25: 13 cut or sold outQ2 25Q3 25: 17 bought or addedQ3 25: 9 cut or sold outQ4 25: 20 bought or addedQ4 25: 12 cut or sold outQ4 25Q1 26: 22 bought or addedQ1 26: 11 cut or sold outQ2 26: 26 bought or addedQ2 26: 14 cut or sold outQ2 26
Numbers
QuarterBought or addedCut or sold out
Q3 2024613
Q4 20241211
Q1 20251313
Q2 2025713
Q3 2025179
Q4 20252012
Q1 20262211
Q2 20262614

Calls vs puts

Options held, notional value, last 4 quarters. P/C = puts ÷ calls

CallsPuts
$0$500k$1m$1.5mQ3 25 calls: $247.1kQ3 25 puts: $0Q3 25P/C 0.00Q4 25 calls: $979.4kQ4 25 puts: $1.0mQ4 25P/C 1.06Q1 26 calls: $78.3kQ1 26 puts: $86.5kQ1 26P/C 1.10Q2 26 calls: $114.8kQ2 26 puts: $111.4kQ2 26P/C 0.97
Numbers
QuarterCallsPutsP/C
Q3 2025$247.1k$00.00
Q4 2025$979.4k$1.0m1.06
Q1 2026$78.3k$86.5k1.10
Q2 2026$114.8k$111.4k0.97

Biggest buyers

Nantahala Capital Management, LLC Added +3,492,519+3.5m
Rosalind Advisors, Inc. Added +1,815,585+1.8m
CANTOR FITZGERALD, L. P. Added +887,481+887.5k
Dauntless Investment Group, LLC Added +310,817+310.8k
VANGUARD CAPITAL MANAGEMENT LLC Added +260,266+260.3k
Shay Capital LLC Added +155,681+155.7k
UBS Group AG Added +116,092+116.1k
GSA CAPITAL PARTNERS LLP Added +115,567+115.6k
Universal- Beteiligungs- und Servicegesellschaft mbH New +50,000+50.0k
VANGUARD FIDUCIARY TRUST CO Added +29,967+30.0k

Biggest sellers

Empery Asset Management, LP Sold out -590,481-590.5k
RENAISSANCE TECHNOLOGIES LLC Reduced -124,455-124.5k
CITADEL ADVISORS LLC Sold out -106,151-106.2k
AIGH Capital Management LLC Reduced -60,000-60.0k
Caption Management, LLC Reduced -46,851-46.9k
AlphaCore Capital LLC Sold out -20,670-20.7k
HRT FINANCIAL LP Sold out -19,090-19.1k
MAI Capital Management Sold out -3,314-3.3k
TWO SIGMA SECURITIES, LLC Reduced -2,875-2.9k
Values First Advisors, Inc. Reduced -1,832-1.8k

Biggest calls

CITADEL ADVISORS LLC Added $60.6k58.8k shares
SUSQUEHANNA INTERNATIONAL GROUP, LLP Added $22.7k22.0k shares
JANE STREET GROUP, LLC Reduced $20.1k19.5k shares
SIMPLEX TRADING, LLC Added $7.6k7.4k shares
GROUP ONE TRADING LLC Reduced $3.9k3.8k shares

Biggest puts

CITADEL ADVISORS LLC Reduced $61.6k59.8k shares
JANE STREET GROUP, LLC Added $29.1k28.3k shares
SIMPLEX TRADING, LLC Added $20.7k20.1k shares

Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.

Major shareholders (over 5%)

Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.

HolderStakeChangeShares Last filed
CorMedix Inc. 13D · may seek influence new · filed 2025-09-12
Stated purposeOn September 7, 2025, the Issuer entered into a securities purchase agreement (the "Purchase Agreement") with the Reporting Person, pursuant to which the Reporting Person purchased from the Issuer in a private placement 9,090,909 Shares at a purchase price of $0.55 per share upon the First Closing (as defined in the Purchase Agreement). The First Closing occurred on September 10, 2025. Upon the First Closing, the Reporting Person has the right, subject to compliance with the applicable rules and regulations of The Nasdaq Capital Market, to designate one member of the Issuer's board of directors as long as the Reporting Person or its affiliates beneficially own at least 25% of the Shares the Reporting Person purchased at the First Closing. Additionally, pursuant to the Purchase Agreement,… Full filing
19.9% new 9.1m≈ $9.4m 2025-09-12
Nantahala Capital Management, LLC 13D · may seek influence no change · filed 2025-04-03 11.7% no change 2.0m≈ $2.1m 2025-04-03
Rosalind Advisors, Inc. 13G · exempt (held before listing) no change · filed 2026-08-12 9.9% no change 12.9m≈ $5.8m 2026-08-12
HIRSCHMAN ORIN 13G · institution +0.1 pts · filed 2026-01-30 9.8% +0.1 pts 4.7m≈ $4.8m 2026-01-30
Rock Springs Capital Management LP 13G · passive investor new · filed 2025-09-12 7.9% new 3.6m≈ $3.7m 2025-09-12

Fell to 5% or below in the last year: LYTTON LAURENCE W (2.5%, 2026-05-15)

Insider purchases and sales since 1 Apr 2026

Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.

Officers and directors buying vs selling

Number of people, by quarter (10% owners not included)

BuyingSelling
404Q4 24: 1 buyingQ4 24: 1 sellingQ1 25: 0 buyingQ1 25: 0 sellingQ1 25Q2 25: 1 buyingQ2 25: 0 sellingQ3 25: 0 buyingQ3 25: 0 sellingQ3 25Q4 25: 0 buyingQ4 25: 0 sellingQ1 26: 4 buyingQ1 26: 0 sellingQ1 26Q2 26: 0 buyingQ2 26: 0 sellingQ3 26: 0 buyingQ3 26: 0 sellingQ3 26
Numbers
QuarterBuyingBoughtSellingSoldSold under a plan
Q4 20241$6.8k1$119—
Q1 20250—0——
Q2 20251$125.9k0——
Q3 20250—0——
Q4 20250—0——
Q1 20264$276.0k0——
Q2 20260—0——
Q3 20260—0——

None reported since 1 Apr 2026.

Holders, Q2 2026

#ManagerLocationShares Value% of their portfolioChangeShares change
1 Nantahala Capital Management, LLC 0.22% of their portfolio NEW CANAAN, CT 6,985,0387.0m $7.2m $7.2m 0.22% Added +3.5m +3,492,519
2 Rosalind Advisors, Inc. 2.00% of their portfolio TORONTO, A6 5,169,5015.2m $5.3m $5.3m 2.00% Added +1.8m +1,815,585
3 AIGH Capital Management LLC 0.43% of their portfolio BALTIMORE, MD 4,601,5024.6m $4.7m $4.7m 0.43% Reduced -60.0k -60,000
4 Rock Springs Capital Management LP 0.18% of their portfolio Baltimore, MD 3,589,1863.6m $3.7m $3.7m 0.18% Unchanged
5 CANTOR FITZGERALD, L. P. 0.02% of their portfolio NEW YORK, NY 1,774,9621.8m $1.8m $1.8m 0.02% Added +887.5k +887,481
6 Bleichroeder LP 0.24% of their portfolio NEW YORK, NY 1,307,7871.3m $1.3m $1.3m 0.24% Unchanged
7 Dauntless Investment Group, LLC 1.33% of their portfolio Milford, MI 746,051746.1k $768.4k $768.4k 1.33% Added +310.8k +310,817
8 VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio MALVERN, PA 701,877701.9k $722.9k $722.9k 0.00% Added +260.3k +260,266
9 Caption Management, LLC 0.02% of their portfolio OKLAHOMA CITY, OK 514,969515.0k $530.4k $530.4k 0.02% Reduced -46.9k -46,851
10 Almitas Capital LLC 0.12% of their portfolio SANTA MONICA, CA 467,152467.2k $481.2k $481.2k 0.12% Unchanged
11 GEODE CAPITAL MANAGEMENT, LLC 0.00% of their portfolio BOSTON, MA 429,062429.1k $442.0k $442.0k 0.00% Added +9.1k +9,082
12 Shay Capital LLC 0.05% of their portfolio NEW YORK, NY 405,764405.8k $417.9k $417.9k 0.05% Added +155.7k +155,681
13 VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio MALVERN, PA 222,372222.4k $229.0k $229.0k 0.00% Added +30.0k +29,967
14 GSA CAPITAL PARTNERS LLP 0.01% of their portfolio LONDON, X0 209,355209.4k $216.0k $216.0k 0.01% Added +115.6k +115,567
15 DIADEMA PARTNERS LP 0.06% of their portfolio MORRISTOWN, NJ 153,563153.6k $158.2k $158.2k 0.06% Unchanged
16 UBS Group AG 0.00% of their portfolio ZURICH, V8 129,916129.9k $133.8k $133.8k 0.00% Added +116.1k +116,092
17 RENAISSANCE TECHNOLOGIES LLC 0.00% of their portfolio NEW YORK, NY 113,300113.3k $116.7k $116.7k 0.00% Reduced -124.5k -124,455
18 Mariner, LLC 0.00% of their portfolio Overland Park, KS 100,000100.0k $103.0k $103.0k 0.00% Unchanged
19 BlackRock, Inc. 0.00% of their portfolio New York, NY 91,54891.5k $94.3k $94.3k 0.00% Unchanged
20 NORTHERN TRUST CORP 0.00% of their portfolio CHICAGO, IL 88,29688.3k $90.9k $90.9k 0.00% Unchanged
21 Values First Advisors, Inc. 0.04% of their portfolio JOHNSON CITY, TN 79,68579.7k $82.1k $82.1k 0.04% Reduced -1.8k -1,832
22 SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio BALA CYNWYD, PA 75,69175.7k $78.0k $78.0k 0.00% Added +25.1k +25,075
23 Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% of their portfolio FRANKFURT AM MAIN, 2M 50,00050.0k $51.5k $51.5k 0.00% New
24 Persistent Asset Partners Ltd 0.01% of their portfolio HONG KONG, K3 38,96839.0k $40.1k $40.1k 0.01% Unchanged
25 Vanguard Global Advisers, LLC 0.00% of their portfolio MALVERN, PA 29,66129.7k $30.6k $30.6k 0.00% Unchanged
26 GOLDMAN SACHS GROUP INC 0.00% of their portfolio NEW YORK, NY 28,43528.4k $29.3k $29.3k 0.00% New
27 XTX Topco Ltd 0.00% of their portfolio LONDON, X0 28,19428.2k $29.0k $29.0k 0.00% Added +2.4k +2,447
28 STATE STREET CORP 0.00% of their portfolio BOSTON, MA 22,18222.2k $22.8k $22.8k 0.00% Unchanged
29 TWO SIGMA SECURITIES, LLC 0.00% of their portfolio NEW YORK, NY 15,78815.8k $16.3k $16.3k 0.00% Reduced -2.9k -2,875
30 STEPHENS INC /AR/ 0.00% of their portfolio LITTLE ROCK, AR 15,13315.1k $15.6k $15.6k 0.00% New
31 WEALTH ENHANCEMENT ADVISORY SERVICES, LLC 0.00% of their portfolio PLYMOUTH, MN 12,50012.5k $18.2k $18.2k 0.00% New
32 Onyx Bridge Wealth Group LLC 0.00% of their portfolio TARRYTOWN, NY 11,50011.5k $11.8k $11.8k 0.00% Unchanged
33 JANE STREET GROUP, LLC 0.00% of their portfolio NEW YORK, NY 10,65410.7k $11.0k $11.0k 0.00% New
34 Virtu Financial LLC 0.00% of their portfolio New York, NY 10,14210.1k $10.0k $10.0k 0.00% New
35 GROUP ONE TRADING LLC 0.00% of their portfolio CHICAGO, IL 8,2138.2k $8.5k $8.5k 0.00% Added +1.5k +1,537
36 JPMORGAN CHASE & CO 0.00% of their portfolio NEW YORK, NY 4,5444.5k $4.8k $4.8k 0.00% New
37 Steward Partners Investment Advisory, LLC 0.00% of their portfolio STAMFORD, CT 1,0001.0k $1.0k $1.0k 0.00% New
38 BARCLAYS PLC 0.00% of their portfolio LONDON, X0 961961 $990 $990 0.00% New
39 WELLS FARGO & COMPANY/MN 0.00% of their portfolio SAN FRANCISCO, CA 600600 $618 $618 0.00% Reduced -383 -383
40 OSAIC HOLDINGS, INC. 0.00% of their portfolio SCOTTSDALE, AZ 285285 $293 $293 0.00% Unchanged
41 NewEdge Advisors, LLC 0.00% of their portfolio NEW ORLEANS, LA 201201 $207 $207 0.00% New
42 BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio PARIS, I0 136136 $140 $140 0.00% Unchanged
43 SBI Securities Co., Ltd. 0.00% of their portfolio TOKYO, M0 115115 $118 $118 0.00% Added +2 +2
44 Arax Advisory Partners 0.00% of their portfolio NEW YORK, NY 8181 $83 $83 0.00% Unchanged
45 Larson Financial Group LLC 0.00% of their portfolio ST LOUIS, MO 3030 $31 $31 0.00% Unchanged
46 MORGAN STANLEY 0.00% of their portfolio NEW YORK, NY 1010 $10 $10 0.00% Unchanged
47 BESSEMER GROUP INC 0.00% of their portfolio WOODBRIDGE, NJ 55 $0 $0 0.00% New
48 FLAGSHIP WEALTH ADVISORS, LLC 0.00% of their portfolio WAKEFIELD, MA 55 $5 $5 0.00% New
49 Global Retirement Partners, LLC 0.00% of their portfolio San Rafael, CA 11 $1 $1 0.00% First filing