GRACE THERAPEUTICS INC GRCE
COM · Common Stock · CUSIP 00439U104
- SectorHealth care
- IndustryPharmaceutical Preparations
- HeadquartersPrinceton, NJ
- FilingsSEC EDGAR
* Summed across managers. Shares that two managers' reports both contain – a subsidiary's holdings that its parent's report includes too, or a sub-adviser's in its client's – are counted once. Holder counts are more reliable. Shares outstanding: 16.3m as of 2026-06-15, from the company's own SEC filing; the percentage can still exceed 100%: lent-out shares are counted by the lender and the buyer, and some reports overlap without saying so. Implied quarter-end price ≈ $2.27. Options: 5 managers hold calls ($666.9k notional), 0 hold puts (—).
Trends to Q2 2026
Institutional holders
Managers reporting a position, each quarter
Numbers
| Quarter | Holders |
|---|---|
| Q3 2024 | 1 |
| Q4 2024 | 16 |
| Q1 2025 | 18 |
| Q2 2025 | 21 |
| Q3 2025 | 20 |
| Q4 2025 | 22 |
| Q1 2026 | 34 |
| Q2 2026 | 33 |
Buyers vs sellers
Managers adding to or starting a position, vs cutting or selling out
Numbers
| Quarter | Bought or added | Cut or sold out |
|---|---|---|
| Q4 2024 | 13 | 1 |
| Q1 2025 | 8 | 8 |
| Q2 2025 | 7 | 8 |
| Q3 2025 | 6 | 6 |
| Q4 2025 | 12 | 5 |
| Q1 2026 | 22 | 9 |
| Q2 2026 | 22 | 15 |
Calls vs puts
Options held, notional value, last 4 quarters. P/C = puts ÷ calls
Numbers
| Quarter | Calls | Puts | P/C |
|---|---|---|---|
| Q3 2025 | $0 | $0 | — |
| Q4 2025 | $0 | $0 | — |
| Q1 2026 | $326.0k | $314.4k | 0.96 |
| Q2 2026 | $666.9k | $0 | 0.00 |
Biggest buyers
| CITADEL ADVISORS LLC | Added | +251.0k |
| CANTOR FITZGERALD, L. P. | New | +200.0k |
| Maven Securities LTD | New | +200.0k |
| TWO SIGMA INVESTMENTS, LP | New | +96.9k |
| Birchview Capital, LP | Added | +70.0k |
| HRT FINANCIAL LP | New | +62.7k |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | New | +49.6k |
| BlackRock, Inc. | New | +37.5k |
| Rangeley Capital, LLC | New | +26.0k |
| Eversept Partners, LP | Added | +16.3k |
Biggest sellers
| Nantahala Capital Management, LLC | Sold out | -728.2k |
| RENAISSANCE TECHNOLOGIES LLC | Sold out | -243.9k |
| MARSHALL WACE, LLP | Sold out | -91.4k |
| Connective Capital Management, LLC | Sold out | -84.5k |
| JANE STREET GROUP, LLC | Reduced | -77.7k |
| Quadrature Capital Ltd | Sold out | -66.8k |
| Diametric Capital, LP | Sold out | -39.8k |
| Pale Fire Capital SE | Sold out | -37.8k |
| PRELUDE CAPITAL MANAGEMENT, LLC | Sold out | -10.1k |
| UBS Group AG | Reduced | -9.5k |
Biggest calls
| GROUP ONE TRADING LLC | New | $278.5k122.7k shares |
| JANE STREET GROUP, LLC | New | $163.7k72.1k shares |
| CITADEL ADVISORS LLC | New | $119.2k52.5k shares |
| SIMPLEX TRADING, LLC | Added | $76.0k33.5k shares |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Reduced | $29.5k13.0k shares |
Biggest puts
| None |
Options at notional value: the value of the shares the contracts control, as filers report them, not what the options cost. Not included in the holders, shares or buying above.
Major shareholders (over 5%)
Anyone who owns more than 5% of a class of the company's shares has to say so: on Schedule 13D if they may try to influence or control the company, on 13G if they're a passive investor, and update it as the stake changes. Each holder's latest filing, from 19 Dec 2024 on; percentages are of the share class, as the holder worked them out.
| Holder | Stake |
|---|---|
| Opaleye Management Inc. 13G · passive investor new · filed 2026-08-07 | 13.1% |
| ADAR1 Capital Management, LLC 13G · institution no change · filed 2026-08-14 | 9.9% |
| Nantahala Capital Management, LLC 13G · institution -3.2 pts · filed 2026-08-14 | 6.8% |
Fell to 5% or below in the last year: HIRSCHMAN ORIN (4.9%, 2026-04-27)
Insider purchases and sales since 1 Apr 2026
Shares bought or sold by the company's own officers, directors and 10% owners, in the open market or privately, as they reported to the SEC on Form 4 (due within two business days of the trade). Grants, option exercises, shares withheld for tax and gifts aren't included.
Officers and directors buying vs selling
Number of people, by quarter (10% owners not included)
Numbers
| Quarter | Buying | Bought | Selling | Sold | Sold under a plan |
|---|---|---|---|---|---|
| Q4 2024 | 0 | — | 0 | — | — |
| Q1 2025 | 0 | — | 0 | — | — |
| Q2 2025 | 0 | — | 0 | — | — |
| Q3 2025 | 0 | — | 0 | — | — |
| Q4 2025 | 0 | — | 0 | — | — |
| Q1 2026 | 0 | — | 0 | — | — |
| Q2 2026 | 0 | — | 0 | — | — |
| Q3 2026 | 1 | $214.0k | 0 | — | — |
| Date | Insider | Trade | Value |
|---|---|---|---|
| 2026-09-23 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $11.2k5.3k shares |
| 2026-09-21 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $20.5k9.8k shares |
| 2026-09-09 | Kohli Prashant Chief Executive Officer, director | Bought | $214.0k100.0k shares |
| 2026-09-09 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $12.2k5.8k shares |
| 2026-09-08 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $19.7k9.4k shares |
| 2026-08-14 | Opaleye Management Inc. 10% owner · By Opaleye, L.P. | Bought | $24.3k11.6k shares |
Their holding: how much the trade added to or took from the insider's holding (direct, or the trust or fund named). The same trade is sometimes reported by more than one insider, such as a fund and the director who represents it; totals count it once. A value is left blank where the reported price is far from the market price (usually a typo).
Holders, Q2 2026
| Manager | Shares | Change |
|---|---|---|
| Cerity Partners LLC 0.00% of their portfolio | 849.1k $1.9m | Unchanged |
| Eversept Partners, LP 0.10% of their portfolio | 772.9k $1.8m | Added +16.3k |
| BANK OF AMERICA CORP /DE/ 0.00% of their portfolio | 494.7k $1.1m | Reduced -25 |
| VANGUARD CAPITAL MANAGEMENT LLC 0.00% of their portfolio | 411.7k $934.6k | Added +10.1k |
| CITADEL ADVISORS LLC 0.00% of their portfolio | 349.7k $793.9k | Added +251.0k |
| CANTOR FITZGERALD, L. P. 0.00% of their portfolio | 200.0k $454.0k | New |
| Maven Securities LTD 0.04% of their portfolio | 200.0k $454.0k | New |
| Birchview Capital, LP 0.13% of their portfolio | 120.0k $272.4k | Added +70.0k |
| TWO SIGMA INVESTMENTS, LP 0.00% of their portfolio | 96.9k $219.9k | New |
| JANE STREET GROUP, LLC 0.00% of their portfolio | 89.4k $203.0k | Reduced -77.7k |
| XTX Topco Ltd 0.00% of their portfolio | 71.7k $162.7k | Added +8.6k |
| HRT FINANCIAL LP 0.00% of their portfolio | 62.7k $142.0k | New |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP 0.00% of their portfolio | 49.6k $112.5k | New |
| BlackRock, Inc. 0.00% of their portfolio | 37.5k $85.2k | New |
| Rangeley Capital, LLC 0.05% of their portfolio | 26.0k $59.0k | New |
| KESTRA PRIVATE WEALTH SERVICES, LLC 0.00% of their portfolio | 23.0k $52.2k | Added +10.0k |
| UBS Group AG 0.00% of their portfolio | 16.8k $38.1k | Reduced -9.5k |
| Stratos Investment Management, LLC 0.00% of their portfolio | 11.2k $25.3k | New |
| BNP PARIBAS FINANCIAL MARKETS 0.00% of their portfolio | 10.5k $23.8k | Added +3.4k |
| Scientech Research LLC 0.02% of their portfolio | 10.2k $23.1k | New |
| Virtu Financial LLC 0.00% of their portfolio | 10.2k $23.0k | New |
| OPPENHEIMER & CO INC 0.00% of their portfolio | 10.0k $22.7k | Unchanged |
| MORGAN STANLEY 0.00% of their portfolio | 9.4k $21.4k | Added +4.9k |
| VANGUARD FIDUCIARY TRUST CO 0.00% of their portfolio | 8.8k $19.9k | Unchanged |
| NATIONAL BANK OF CANADA /FI/ 0.00% of their portfolio | 2.7k $6.1k | Reduced -36 |
| WELLS FARGO & COMPANY/MN 0.00% of their portfolio | 1.8k $4.1k | Unchanged |
| Tower Research Capital LLC (TRC) 0.00% of their portfolio | 1.7k $3.8k | Added +1.2k |
| Arax Advisory Partners 0.00% of their portfolio | 1.0k $2.3k | Added +500 |
| ROYAL BANK OF CANADA 0.00% of their portfolio | 543 $1.0k | Unchanged |
| Activest Wealth Management 0.00% of their portfolio | 104 $236 | Unchanged |
| SBI Securities Co., Ltd. 0.00% of their portfolio | 77 $175 | Added +7 |
| Federation des caisses Desjardins du Quebec 0.00% of their portfolio | 41 $93 | Added +40 |
| LANARK FINANCIAL, INC. 0.00% of their portfolio | 2 $4 | Unchanged |